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Reappraisal of the historical selective pressures for the CCR5-Delta32 mutation
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title
Reappraisal of the historical selective pressures for the CCR5-Delta32 mutation
(English)
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author name string
S R Duncan
series ordinal
1
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S Scott
series ordinal
2
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C J Duncan
series ordinal
3
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language of work or name
English
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publication date
March 2005
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published in
Journal of Medical Genetics
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volume
42
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issue
3
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page(s)
205-8
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cites work
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Use of chemokine receptors by poxviruses
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Dating the origin of the CCR5-Delta32 AIDS-resistance allele by the coalescence of haplotypes
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7 April 2017
Identification of a major co-receptor for primary isolates of HIV-1
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A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors
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7 April 2017
Evolutionary genetics: CCR5 mutation and plague protection
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7 April 2017
The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
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7 April 2017
CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1
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Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
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Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.
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Homozygous and heterozygous CCR5-Delta32 genotypes are associated with resistance to HIV infection.
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The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe.
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The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression
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28 September 2017
Viral haemorrhagic fevers in ancient Mesopotamia
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30 May 2018
The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.
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28 November 2018
Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene
1 reference
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reference URL
https://pubmed.ncbi.nlm.nih.gov/15744032
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1136/JMG.2004.025346
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PMC publication ID
1736018
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PubMed publication ID
15744032
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ResearchGate publication ID
7990109
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