(Q24675633)

English

Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling

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scholarly article

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Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling (English)

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1 reference

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author name string

A B Schromm

1

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E Lien

2

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P Henneke

3

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J C Chow

4

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A Yoshimura

5

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H Heine

6

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E Latz

7

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B G Monks

8

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D A Schwartz

9

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K Miyake

10

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D T Golenbock

11

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language of work or name

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publication date

2 July 2001

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Journal of Experimental Medicine

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194

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1

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79-88

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Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation

1 reference

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7 April 2017

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

1 reference

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7 April 2017

A family of human receptors structurally related to Drosophila Toll

1 reference

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1 reference

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7 April 2017

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

1 reference

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7 April 2017

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

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7 April 2017

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

1 reference

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7 April 2017

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

1 reference

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7 April 2017

Lipopolysaccharide-binding protein is required to combat a murine gram-negative bacterial infection

1 reference

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7 April 2017

TRAF6 is a signal transducer for interleukin-1

1 reference

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7 April 2017

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

1 reference

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7 April 2017

Cutting edge: functional characterization of the effect of the C3H/HeJ defect in mice that lack an Lpsn gene: in vivo evidence for a dominant negative mutation

1 reference

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7 April 2017

Involvement of a NF-kappa B-like transcription factor in the activation of the interleukin-6 gene by inflammatory lymphokines

1 reference

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7 April 2017

Lipopolysaccharide (LPS) partial structures inhibit responses to LPS in a human macrophage cell line without inhibiting LPS uptake by a CD14-mediated pathway

1 reference

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7 April 2017

pEF-BOS, a powerful mammalian expression vector

1 reference

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7 April 2017

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

7 April 2017

MD-2 binds to bacterial lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

28 September 2017

Cellular events mediated by lipopolysaccharide-stimulated toll-like receptor 4. MD-2 is required for activation of mitogen-activated protein kinases and Elk-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

28 September 2017

The biology of Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

28 September 2017

Biological activities of lipopolysaccharides are determined by the shape of their lipid A portion

1 reference

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28 September 2017

Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide

1 reference

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28 September 2017

Bacterial lipopolysaccharide induces expression of the stress response genes hop and H411.

1 reference

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28 September 2017

Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

28 September 2017

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

28 September 2017

Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

28 September 2017

Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

28 September 2017

Construction of a lipopolysaccharide reporter cell line and its use in identifying mutants defective in endotoxin, but not TNF-alpha, signal transduction

1 reference

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Epidemiology of sepsis syndrome in 8 academic medical centers

1 reference

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28 September 2017

Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

28 September 2017

CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

28 September 2017

Synthetic lipid A with endotoxic and related biological activities comparable to those of a natural lipid A from an Escherichia coli re-mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

28 September 2017

Gram-negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

28 September 2017

The pathogenesis of sepsis

1 reference

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28 September 2017

Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in the Drosophila embryo

1 reference

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28 September 2017

CD14 is a pattern recognition receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

28 September 2017

Surface expression of human CD14 in Chinese hamster ovary fibroblasts imparts macrophage-like responsiveness to bacterial endotoxin

1 reference

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30 May 2018

Establishment of dorsal-ventral polarity in the Drosophila embryo: genetic studies on the role of the Toll gene product.

1 reference

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30 May 2018

Production of hybridoma growth factor by human monocytes.

1 reference

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30 May 2018

Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages

1 reference

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30 May 2018

Cutting edge: cells that carry A null allele for toll-like receptor 2 are capable of responding to endotoxin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193443

28 November 2018

Unresponsiveness of MyD88-deficient mice to endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11435474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide-binding protein and soluble CD14 transfer lipopolysaccharide to phospholipid bilayers: preferential interaction with particular classes of lipid

1 reference

https://pubmed.ncbi.nlm.nih.gov/11435474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Innate immune recognition of bacterial lipopolysaccharide: dependence on interactions with membrane lipids and endocytic movement

1 reference

https://pubmed.ncbi.nlm.nih.gov/11435474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.194.1.79

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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