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AP-2gamma induces p21 expression, arrests cell cycle, and inhibits the tumor growth of human carcinoma cells
scientific article
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
1601932
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867219%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
title
AP-2gamma induces p21 expression, arrests cell cycle, and inhibits the tumor growth of human carcinoma cells
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
1601932
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867219%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
author
Prabhat C Goswami
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
1601932
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867219%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Frederick E. Domann
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
1601932
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867219%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
author name string
Hualei Li
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
1601932
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867219%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
language of work or name
English
0 references
publication date
1 July 2006
1 reference
stated in
Europe PubMed Central
PMC publication ID
1601932
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867219%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
published in
Neoplasia
1 reference
stated in
Europe PubMed Central
PMC publication ID
1601932
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867219%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
volume
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
1601932
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867219%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
1601932
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867219%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
page(s)
568-577
1 reference
stated in
Europe PubMed Central
PMC publication ID
1601932
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867219%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
cites work
Transcription factor gene AP-2 gamma essential for early murine development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
7 April 2017
Transcription factor AP-2alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
7 April 2017
A family of AP-2 proteins down-regulate manganese superoxide dismutase expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
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7 April 2017
RB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
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7 April 2017
Cloning and characterization of a second AP-2 transcription factor: AP-2 beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
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7 April 2017
The retinoblastoma protein and cell cycle control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
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7 April 2017
Minireview: PRKAR1A: normal and abnormal functions
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PubMed Central
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7 April 2017
Cloning and characterization of a novel mouse AP-2 transcription factor, AP-2delta, with unique DNA binding and transactivation properties
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
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7 April 2017
Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
7 April 2017
Transcription factor AP-2 essential for cranial closure and craniofacial development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
7 April 2017
Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
7 April 2017
AP-2alpha transcription factor is required for early morphogenesis of the lens vesicle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
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7 April 2017
AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
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7 April 2017
Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
7 April 2017
AP-2alpha and AP-2gamma are transcriptional targets of p53 in human breast carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Regulation of KiSS-1 metastasis suppressor gene expression in breast cancer cells by direct interaction of transcription factors activator protein-2alpha and specificity protein-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Transcription factor AP-2gamma, a novel marker of gonocytes and seminomatous germ cell tumors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Minireview: Cyclin D1: normal and abnormal functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Hypermethylation of a small CpGuanine-rich region correlates with loss of activator protein-2alpha expression during progression of breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Activator protein 2alpha inhibits tumorigenicity and represses vascular endothelial growth factor transcription in prostate cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Molecular cloning and characterization of AP-2 epsilon, a fifth member of the AP-2 family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
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28 September 2017
Cell cycle arrest and apoptosis induction by activator protein 2alpha (AP-2alpha) and the role of p53 and p21WAF1/CIP1 in AP-2alpha-mediated growth inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Identification of regulatory regions within the KAI1 promoter: a role for binding of AP1, AP2 and p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
p53-dependent downregulation of metastasis-associated laminin receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Tumor suppressor activity of AP2alpha mediated through a direct interaction with p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Dominant negative interference of transcription factor AP-2 causes inhibition of ErbB-3 expression and suppresses malignant cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Gene regulation in melanoma progression by the AP-2 transcription factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Role of AP-2 in tumor growth and metastasis of human melanoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Immunohistochemical analysis reveals a tumour suppressor-like role for the transcription factor AP-2 in invasive breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
AP2alpha and AP2gamma: a comparison of binding site specificity and trans-activation of the estrogen receptor promoter and single site promoter constructs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Identification of AP-2 as an interactive target of Rb and a regulator of the G1/S control element of the hamster histone H3.2 promoter.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 September 2017
Expression of AP-2 transcription factors in human breast cancer correlates with the regulation of multiple growth factor signalling pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
30 May 2018
AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
30 May 2018
Dual role of AP-2? in ErbB-2-induced mammary tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 November 2018
Reduced nuclear expression of transcription factor AP-2 associates with aggressive breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 November 2018
Transcription factor AP-2gamma is essential in the extra-embryonic lineages for early postimplantation development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 November 2018
The retinoblastoma-related Rb2/p130 gene is an effector downstream of AP-2 during neural differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 November 2018
Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1601932
retrieved
28 November 2018
Expression and amplification of cyclin genes in human breast cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16867219
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cyclin D1 protein expression and function in human breast cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16867219
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
AP-2.2, a novel gene related to AP-2, is expressed in the forebrain, limbs and face during mouse embryogenesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16867219
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1593/NEO.06367
1 reference
stated in
Europe PubMed Central
PMC publication ID
1601932
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867219%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
PMC publication ID
1601932
1 reference
stated in
Europe PubMed Central
PMC publication ID
1601932
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867219%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
PubMed publication ID
16867219
1 reference
stated in
Europe PubMed Central
PMC publication ID
1601932
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16867219%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
ResearchGate publication ID
6919485
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