(Q24679781)

English

Selective in vitro replication of herpes simplex virus type 1 (HSV-1) ICP34.5 null mutants in primary human CNS tumours--evaluation of a potentially effective clinical therapy

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scholarly article

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Selective in vitro replication of herpes simplex virus type 1 (HSV-1) ICP34.5 null mutants in primary human CNS tumours--evaluation of a potentially effective clinical therapy (English)

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Herpes simplex virus type 1

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based on heuristic

inferred from title

author name string

E A McKie

1

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A R MacLean

2

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A D Lewis

3

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G Cruickshank

4

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R Rampling

5

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S C Barnett

6

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P G Kennedy

7

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S M Brown

8

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language of work or name

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publication date

September 1996

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British Journal of Cancer

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74

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745-52

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5

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Cell type and cell state determine differential in vitro growth of non-neurovirulent ICP34.5-negative herpes simplex virus types 1 and 2.

1 reference

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Comparison of genetically engineered herpes simplex viruses for the treatment of brain tumors in a scid mouse model of human malignant glioma

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Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas

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Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant.

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The terminal a sequence of the herpes simplex virus genome contains the promoter of a gene located in the repeat sequences of the L component.

1 reference

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Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate.

1 reference

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Herpes simplex virus type 1 deletion variants 1714 and 1716 pinpoint neurovirulence-related sequences in Glasgow strain 17+ between immediate early gene 1 and the 'a' sequence

1 reference

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The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells

1 reference

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Growth of a rat neuroblastoma cell line in serum-free supplemented medium

1 reference

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Physical mapping of herpes simplex virus-induced polypeptides

1 reference

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Treatment of malignant gliomas using ganciclovir-hypersensitive, ribonucleotide reductase-deficient herpes simplex viral mutant

1 reference

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ICP34.5 influences herpes simplex virus type 1 maturation and egress from infected cells in vitro

1 reference

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Treatment of experimental intracranial murine melanoma with a neuroattenuated herpes simplex virus 1 mutant

1 reference

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Reduction and elimination of encephalitis in an experimental glioma therapy model with attenuated herpes simplex mutants that retain susceptibility to acyclovir

1 reference

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Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir

1 reference

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Characterization of the herpes simplex virus type 1 strain 17+ neurovirulence gene RL1 and its expression in a bacterial system

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Purified astrocytes promote the in vitro division of a bipotential glial progenitor cell

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Genetic studies with herpes simplex virus type 1. The isolation of temperature-sensitive mutants, their arrangement into complementation groups and recombination analysis leading to a linkage map.

1 reference

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Chromosomal evolution in malignant human gliomas starts with specific and usually numerical deviations

1 reference

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Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture

1 reference

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Experimental Therapy of Human Glioma by Means of a Genetically Engineered Virus Mutant

1 reference

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Status of the ICP34.5 gene in herpes simplex virus type 1 strain 17

1 reference

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The herpes simplex virus type 1 strain 17+ gamma 34.5 deletion mutant 1716 is avirulent in SCID mice

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Direct measurement of pO2 distribution and bioreductive enzymes in human malignant brain tumors.

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Chemotherapy for malignant gliomas

1 reference

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12 December 2020

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Identifiers

10.1038/BJC.1996.431

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Springer Nature article ID

10.1038/bjc.1996.431

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