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Numb is an endocytic protein
scientific article
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instance of
scholarly article
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title
Numb is an endocytic protein
(English)
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author name string
E Santolini
series ordinal
1
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C Puri
series ordinal
2
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A E Salcini
series ordinal
3
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M C Gagliani
series ordinal
4
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P G Pelicci
series ordinal
5
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C Tacchetti
series ordinal
6
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P P Di Fiore
series ordinal
7
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language of work or name
English
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publication date
11 December 2000
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published in
Journal of Cell Biology
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volume
151
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issue
6
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page(s)
1345-52
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cites work
Mouse numb is an essential gene involved in cortical neurogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
Ocular albinism: evidence for a defect in an intracellular signal transduction system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
Notch signaling: cell fate control and signal integration in development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
LIN-12/Notch signaling: lessons from worms and flies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
The ear of alpha-adaptin interacts with the COOH-terminal domain of the Eps 15 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
Notch signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
7 April 2017
Ligand endocytosis drives receptor dissociation and activation in the Notch pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
28 September 2017
The EH network
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
28 September 2017
Eps15 is recruited to the plasma membrane upon epidermal growth factor receptor activation and localizes to components of the endocytic pathway during receptor internalization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
28 September 2017
Inscuteable and numb mediate asymmetric muscle progenitor cell divisions during Drosophila myogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
28 September 2017
eps15 and eps15R are essential components of the endocytic pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
28 September 2017
The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
28 September 2017
eps15, a novel tyrosine kinase substrate, exhibits transforming activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
28 September 2017
NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
30 May 2018
Assembly of clathrin coats disrupts the association between Eps15 and AP-2 adaptors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
30 May 2018
Requirement for dynamin during Notch signaling in Drosophila neurogenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
30 May 2018
Mapping of the molecular determinants involved in the interaction between eps15 and AP-2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
30 May 2018
The tyrosine kinase substrate eps15 is constitutively associated with the plasma membrane adaptor AP-2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
30 May 2018
numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
30 May 2018
Multiple signalling pathways establish cell fate and cell number in Drosophila malpighian tubules
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
28 November 2018
Notch1 inhibits neurite outgrowth in postmitotic primary neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
28 November 2018
Segregation of myogenic lineages in Drosophila requires numb.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
28 November 2018
Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
28 November 2018
Asymmetric segregation of Numb and Prospero during cell division
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2190585
retrieved
28 November 2018
Contact-dependent inhibition of cortical neurite growth mediated by notch signaling
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11121447
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1083/JCB.151.6.1345
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PMCID
2190585
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PubMed ID
11121447
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ResearchGate publication ID
12208128
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