(Q24684962)

English

Loss of the EP2 prostaglandin E2 receptor in immortalized human keratinocytes results in increased invasiveness and decreased paxillin expression

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scholarly article

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Loss of the EP2 prostaglandin E2 receptor in immortalized human keratinocytes results in increased invasiveness and decreased paxillin expression (English)

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1 reference

based on heuristic

inferred from title

prostaglandin E2

1 reference

based on heuristic

inferred from title

author name string

Raymond L Konger

1

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Glynis A Scott

2

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Yvonne Landt

3

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Jack H Ladenson

4

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Alice P Pentland

5

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language of work or name

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publication date

December 2002

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The American Journal of Pathology

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161

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6

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2065-78

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Cyclooxygenase-2 expression and prostaglandin E(2) synthesis are up-regulated in carcinomas of the cervix: a possible autocrine/paracrine regulation of neoplastic cell function via EP2/EP4 receptors

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Importance of the extracellular domain for prostaglandin EP(2) receptor function

1 reference

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Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps

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Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis

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Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice

1 reference

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Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype

1 reference

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Expressions of cyclooxygenase-2 and prostaglandin E-receptors in carcinoma of the gallbladder: crucial role of arachidonate metabolism in tumor growth and progression.

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Expression of cyclooxygenase 2 is an independent prognostic factor in human ovarian carcinoma

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Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis.

1 reference

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Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer

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Comparison of agonist-induced internalization of the human EP2 and EP4 prostaglandin receptors: role of the carboxyl terminus in EP4 receptor sequestration.

1 reference

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1 reference

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Role of the cytoskeletal protein paxillin in oncogenesis

1 reference

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Cyclooxygenase-2 and carcinogenesis

1 reference

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Differential regulation of prostaglandin F(2alpha) receptor isoforms by protein kinase C.

1 reference

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1 reference

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The prostacyclin receptor is isoprenylated. Isoprenylation is required for efficient receptor-effector coupling.

1 reference

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Apoptosis in proliferating, senescent, and immortalized keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850902

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Alterations in focal adhesion kinase activity and associated proteins during malignant conversion of mouse keratinocytes

1 reference

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Reconstruction of a human skin equivalent using a spontaneously transformed keratinocyte cell line (HaCaT).

1 reference

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Regulation of cytoskeleton organization and paxillin dephosphorylation by cAMP. Studies on murine Y1 adrenal cells

1 reference

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Acetylsalicylic acid (ASA) protects the prostaglandin-cAMP-system of human hypernephroma cells against irradiation-induced alterations

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Human hepatocellular cancers show decreased prostaglandin E1 binding capacity

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1 reference

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Size- and invasion-dependent increase in cyclooxygenase 2 levels in human colorectal carcinomas

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Indomethacin therapy abrogates the prostaglandin-mediated suppression of natural killer activity in tumor-bearing mice and prevents tumor metastasis.

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1 reference

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1 reference

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1 reference

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COX-2 is expressed in human pulmonary, colonic, and mammary tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850902

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850902

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Expression of the focal adhesion protein paxillin in lung cancer and its relation to cell motility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850902

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850902

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850902

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850902

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Elevated COX-2 expression in cervical carcinoma: reduced cause-specific survival and pelvic control

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964485-9

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Cyclooxygenase-2 overexpression enhances lymphatic invasion and metastasis in human gastric carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964485-9

7 January 2021

Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964485-9

7 January 2021

Growth regulation of primary human keratinocytes by prostaglandin E receptor EP2 and EP3 subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964485-9

7 January 2021

Depth of invasion parallels increased cyclooxygenase-2 levels in patients with gastric carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964485-9

7 January 2021

Down-regulation of prostaglandin E2 receptors in regenerating rat liver and its physiological significance

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964485-9

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Alteration of prostaglandin E receptors in advanced breast tumour cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964485-9

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Prostaglandin deficiency promotes sensitization of adenylyl cyclase

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964485-9

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Cyclic AMP-mediated inhibition of angiotensin II-induced protein synthesis is associated with suppression of tyrosine phosphorylation signaling in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964485-9

7 January 2021

Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of prostaglandin E receptors during progression of rat mammary tumors from hormonal dependence to autonomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the prostaglandin E2 receptor in mammary tumor metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of brain PGE2 and PGF2 alpha receptors and receptor-coupled second messengers by cyclooxygenase inhibition in newborn pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent down-regulation of EP2 and EP3 subtypes of the prostaglandin E2 receptors on U937 human monocytic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12466123

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/S0002-9440(10)64485-9

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