(Q24685070)

2

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Kenneth J Ritchie

3

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Ikuya Sakai

4

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Kasuto Takeuchi

5

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Ruibao Ren

6

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Dong-Er Zhang

UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity

7

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language of work or name

English

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publication date

1 July 2007

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published in

Blood

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volume

110

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issue

1

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page(s)

305-12

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cites work

1 reference

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Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation

7 April 2017

1 reference

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The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

Protein ISGylation modulates the JAK-STAT signaling pathway

7 April 2017

1 reference

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The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3

7 April 2017

1 reference

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TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B

7 April 2017

1 reference

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Cloning and characterization of a novel human ubiquitin-specific protease, a homologue of murine UBP43 (Usp18)

7 April 2017

1 reference

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Functional role of type I and type II interferons in antiviral defense

7 April 2017

1 reference

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How cells respond to interferons

7 April 2017

1 reference

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

7 April 2017

1 reference

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

7 April 2017

1 reference

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The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

UBP43 (USP18) specifically removes ISG15 from conjugated proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

Ube1L and protein ISGylation are not essential for alpha/beta interferon signaling

7 April 2017

1 reference

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Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia

7 April 2017

1 reference

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ISG15: a ubiquitin-like enigma

7 April 2017

1 reference

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Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis

7 April 2017

1 reference

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Stats: transcriptional control and biological impact

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

STATs and gene regulation

7 April 2017

1 reference

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The immunobiology of cancer immunosurveillance and immunoediting

7 April 2017

1 reference

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Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia

7 April 2017

1 reference

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Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

7 April 2017

1 reference

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Microarray analysis reveals that Type I interferon strongly increases the expression of immune-response related genes in Ubp43 (Usp18) deficient macrophages

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

Effects of imatinib and interferon on primitive chronic myeloid leukaemia progenitors

28 September 2017

1 reference

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Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia

28 September 2017

1 reference

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Mechanisms of transformation by the BCR-ABL oncogene: new perspectives in the post-imatinib era.

28 September 2017

1 reference

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Novel growth and death related interferon-stimulated genes (ISGs) in melanoma: greater potency of IFN-beta compared with IFN-alpha2.

28 September 2017

1 reference

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Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

Dysregulation of protein modification by ISG15 results in brain cell injury

28 September 2017

1 reference

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Signaling via the interferon-alpha receptor in chronic myelogenous leukemia cells

28 September 2017

1 reference

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Chronic myelogenous leukemia: mechanisms underlying disease progression.

28 September 2017

1 reference

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Cancer immunotherapy: the interferon-alpha experience

28 September 2017

1 reference

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Chronic myeloid leukemia and interferon-alpha: a study of complete cytogenetic responders

28 September 2017

1 reference

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Negative regulation of cytokine signaling.

28 September 2017

1 reference

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Interferons alpha and beta as immune regulators--a new look

28 September 2017

1 reference

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Functional classification of interferon-stimulated genes identified using microarrays

28 September 2017

1 reference

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Cloning and characterization of human ubiquitin-processing protease-43 from terminally differentiated human melanoma cells using a rapid subtraction hybridization protocol RaSH.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

Models of chronic myeloid leukemia

28 September 2017

1 reference

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The molecular biology of chronic myeloid leukemia.

28 September 2017

1 reference

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Second-generation interferons for cancer: clinical targets

28 September 2017

1 reference

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Role of the cytoplasmic domains of the type I interferon receptor subunits in signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

RNase-L-dependent destabilization of interferon-induced mRNAs. A role for the 2-5A system in attenuation of the interferon response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons.

28 September 2017

1 reference

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Suppression of cell proliferation and the expression of a bcr-abl fusion gene and apoptotic cell death in a new human chronic myelogenous leukemia cell line, KT-1, by interferon-alpha.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

A direct signaling pathway through tyrosine kinase activation of SH2 domain-containing transcription factors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

Interferon induces a 15-kilodalton protein exhibiting marked homology to ubiquitin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

The interferon-inducible 15-kDa ubiquitin homolog conjugates to intracellular proteins

28 September 2017

1 reference

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Bcr-Abl efficiently induces a myeloproliferative disease and production of excess interleukin-3 and granulocyte-macrophage colony-stimulating factor in mice: a novel model for chronic myelogenous leukemia

28 September 2017

1 reference

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Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of radiosensitivity.

30 May 2018

1 reference

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Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

30 May 2018

1 reference

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Interferon-stimulated genes in interferon-sensitive and -resistant chronic myelogenous leukemia patients

30 May 2018

1 reference

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Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulating type I IFN signaling.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1896118

Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection.

28 November 2018

1 reference

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Discontinuation of imatinib therapy after achieving a molecular response

28 November 2018

1 reference

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Complete cytogenetic and molecular responses to interferon-alpha-based therapy for chronic myelogenous leukemia are associated with excellent long-term prognosis

28 November 2018

1 reference

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Interferon production in myelo- and lymphoproliferative diseases. I. Spontaneous interferon production in acute and chronic leukaemias

28 November 2018

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12 December 2020

Constitutive activation of JAKs and STATs in BCR-Abl-expressing cell lines and peripheral blood cells derived from leukemic patients

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12 December 2020

Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow

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12 December 2020

UBP43, an ISG15-specific deconjugating enzyme: expression, purification, and enzymatic assays

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12 December 2020