(Q24685285)

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Foreign body-type multinucleated giant cell formation is potently induced by alpha-tocopherol and prevented by the diacylglycerol kinase inhibitor R59022

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Foreign body-type multinucleated giant cell formation is potently induced by alpha-tocopherol and prevented by the diacylglycerol kinase inhibitor R59022 (English)

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Amy K McNally

1

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James M Anderson

2

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publication date

September 2003

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The American Journal of Pathology

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163

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3

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1147-56

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Interleukin 4 induces cultured monocytes/macrophages to form giant multinucleated cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

7 April 2017

Properties and functions of diacylglycerol kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

7 April 2017

Selectivity of the diacylglycerol kinase inhibitor 3-[2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl)ethyl]-2, 3-dihydro-2-thioxo-4(1H)quinazolinone (R59949) among diacylglycerol kinase subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

7 April 2017

Vitamin E: function and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

7 April 2017

Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

7 April 2017

Alternative macrophage activation-associated CC-chemokine-1, a novel structural homologue of macrophage inflammatory protein-1 alpha with a Th2-associated expression pattern

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

7 April 2017

The many faces of macrophage activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

7 April 2017

ON THE EXISTENCE OF A HITHERTO UNRECOGNIZED DIETARY FACTOR ESSENTIAL FOR REPRODUCTION.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Biomaterial adherent macrophage apoptosis is increased by hydrophilic and anionic substrates in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Non-antioxidant molecular functions of alpha-tocopherol (vitamin E).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Connective tissue growth factor: a new and important player in the pathogenesis of fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Beta1 and beta2 integrins mediate adhesion during macrophage fusion and multinucleated foreign body giant cell formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

The location and function of vitamin E in membranes (review).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Specific cellular responses to alpha-tocopherol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Vitamin E: non-antioxidant roles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Alternative versus classical activation of macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Multinucleated giant cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Optimal nutrition: vitamin E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Synergism among lysophosphatidic acid, beta1A integrins, and epidermal growth factor or platelet-derived growth factor in mediation of cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

alpha-Tocopherol enrichment of monocytes decreases agonist-induced adhesion to human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Lysophosphatidic acid is a major serum noncytokine survival factor for murine macrophages which acts via the phosphatidylinositol 3-kinase signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Interleukin-4-induced macrophage fusion is prevented by inhibitors of mannose receptor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

The effects of alpha tocopherol supplementation on monocyte function. Decreased lipid oxidation, interleukin 1 beta secretion, and monocyte adhesion to endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Messenger functions of phosphatidic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Modulation of cell surface fibronectin assembly sites by lysophosphatidic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Complement C3 participation in monocyte adhesion to different surfaces

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Interleukin-4 induces foreign body giant cells from human monocytes/macrophages. Differential lymphokine regulation of macrophage fusion leads to morphological variants of multinucleated giant cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Induction of Multinucleated Giant Cell Formation from In Vitro Culture of Human Monocytes with Interleukin-3 and Interferon-γ: Comparison with Other Stimulating Factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Activation of actin polymerization by phosphatidic acid derived from phosphatidylcholine in IIC9 fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 September 2017

Induction of cytosolic phospholipase A2 activity by phosphatidic acid and diglycerides in permeabilized human neutrophils: interrelationship between phospholipases D and A2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

30 May 2018

Vitamin E as an antioxidant for poly(etherurethane urea): in vivo studies. Student Research Award in the Doctoral Degree Candidate Category, Fifth World Biomaterials Congress (22nd Annual Meeting of the Society for Biomaterials), Toronto, Canada, Ma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

30 May 2018

Induction of multinucleated giant cell formation from human blood-derived monocytes by phorbol myristate acetate in in vitro culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

30 May 2018

Role of vitamin E in preventing the oxidation of low-density lipoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

30 May 2018

Cytokine-induced generation of multinucleated giant cells in vitro requires interferon-gamma and expression of LFA-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

30 May 2018

Theoretical analysis on cell size distribution and kinetics of foreign-body giant cell formation in vivo on polyurethane elastomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

30 May 2018

Biomaterial surface chemistry dictates adherent monocyte/macrophage cytokine expression in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 November 2018

Alpha-tocopherol modulates tyrosine phosphorylation in human neutrophils by inhibition of protein kinase C activity and activation of tyrosine phosphatases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 November 2018

Assembly of a fibronectin matrix by adherent platelets stimulated by lysophosphatidic acid and other agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 November 2018

Phospholipase A(2)-mediated fusion of neutrophil-derived membranes is augmented by phosphatidic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 November 2018

Alternatively activated macrophages differentially express fibronectin and its splice variants and the extracellular matrix protein betaIG-H3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868253

28 November 2018

Alkylsilane-modified surfaces: inhibition of human macrophage adhesion and foreign body giant cell formation

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

Influence of biomaterial surface chemistry on the apoptosis of adherent cells

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

Direct evidence that inflammatory multinucleate giant cells form by fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

Foreign-body giant cells and polyurethane biostability: in vivo correlation of cell adhesion and surface cracking

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

Biodegradation of polyether polyurethane inner insulation in bipolar pacemaker leads

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

Macrophages form circular zones of very close apposition to IgG-coated surfaces

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

Role for interleukin-4 in foreign-body giant cell formation on a poly(etherurethane urea) in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

Monocyte, macrophage and foreign body giant cell interactions with molecularly engineered surfaces

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

Adsorbed serum proteins responsible for surface dependent human macrophage behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

Adsorbed IgG: a potent adhesive substrate for human macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

d-Alpha-tocopherol prevents the hyperglycemia induced activation of diacylglycerol (DAG)-protein kinase C (PKC) pathway in vascular smooth muscle cell by an increase of DAG kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

Lysosomal membrane stabilization by alpha-tocopherol against the damaging action of Vipera russelli venom phospholipase A2

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

Differences in angiogenic potential of classically vs alternatively activated macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

Polarized distribution of Na+,K+-ATPase in giant cells elicited in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963474-8

7 January 2021

Phosphatidic Acid and Lysophosphatidic Acid Induce Haptotactic Migration of Human Monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12937156

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of formation of multinucleated giant cells from concanavalin A-stimulated human blood monocytes by IFN-gamma and IL-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/12937156

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-13 induces human monocyte/macrophage fusion and macrophage mannose receptor expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12937156

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of native and modified lipoproteins on migration of mouse peritoneal macrophages and the effect of the antioxidants vitamin E and Probucol

1 reference

https://pubmed.ncbi.nlm.nih.gov/12937156

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1016/S0002-9440(10)63474-8

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