(Q24791178)

5 July 2017

7 references

18 June 2019

19 June 2019

28 September 2019

27 November 2019

13 December 2019

21 December 2019

26 July 2020

What you should know about PR3-ANCA. Conformational requirements of proteinase 3 (PR3) for enzymatic activity and recognition by PR3-ANCA. (English)

1 reference

anti-neutrophil cytoplasmic antibody

5 July 2017

1 reference

28 September 2019

1 reference

27 November 2019

1 reference

13 December 2019

1 reference

21 December 2019

1 reference

26 July 2020

U Specks

1

1 reference

5 July 2017

language of work or name

English

0 references

publication date

12 June 2000

8 references

Arthritis Research and Therapy

5 July 2017

18 June 2019

19 June 2019

28 September 2019

27 November 2019

13 December 2019

21 December 2019

26 July 2020

1 reference

5 July 2017

7 references

18 June 2019

19 June 2019

28 September 2019

27 November 2019

13 December 2019

21 December 2019

26 July 2020

2

1 reference

5 July 2017

issue

4

1 reference

5 July 2017

page(s)

263-267

1 reference

The crystal structure of PR3, a neutrophil serine proteinase antigen of Wegener's granulomatosis antibodies

5 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Epitope mapping of anti-proteinase 3 and anti-myeloperoxidase antibodies

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Proteinase 3. A distinct human polymorphonuclear leukocyte proteinase that produces emphysema in hamsters

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Characterization of proteinase-3 (PR-3), a neutrophil serine proteinase. Structural and functional properties

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Recombinant proteinase 3 produced in different expression systems: recognition by anti-PR3 antibodies

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

A proportion of proteinase 3 (PR3)-specific anti-neutrophil cytoplasmic antibodies (ANCA) only react with PR3 after cleavage of its N-terminal activation dipeptide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Capture-ELISA based on recombinant PR3 is sensitive for PR3-ANCA testing and allows detection of PR3 and PR3-ANCA/PR3 immunecomplexes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G, and proteinase 3: evidence for distinct cleavage sites within the aminoterminal domain of the thrombin receptor.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Characterization of the processing and granular targeting of human proteinase 3 after transfection to the rat RBL or the murine 32D leukemic cell lines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Antibiotic peptides and serine protease homologs in human polymorphonuclear leukocytes: defensins and azurocidin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Structure of the azurocidin, proteinase 3, and neutrophil elastase genes. Implications for inflammation and vasculitis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Inhibition of proteinase 3 by ANCA and its correlation with disease activity in Wegener's granulomatosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

In vitro processing of human tumor necrosis factor-alpha.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Recombinant human proteinase 3, the Wegener's autoantigen, expressed in HMC-1 cells is enzymatically active and recognized by c-ANCA.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Biosynthesis and processing of proteinase 3 in U937 cells. Processing pathways are distinct from those of cathepsin G.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Characterization of a recombinant proteinase 3, the autoantigen in Wegener's granulomatosis and its reactivity with anti-neutrophil cytoplasmic autoantibodies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Expression of the human autoantigen of Wegener's granulomatosis (PR3) in a baculovirus expression system

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Biosynthesis, processing and sorting of neutrophil proteins: insight into neutrophil granule development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Pathogenesis of the vascular and glomerular damage in ANCA-positive vasculitis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Antineutrophil cytoplasmic autoantibodies in Wegener's granulomatosis recognize conformational epitope(s) on proteinase 3

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Interleukin-8 processing by neutrophil elastase, cathepsin G and proteinase-3.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=130016

Proteinase 3, the major autoantigen of Wegener's granulomatosis, enhances IL-8 production by endothelial cells in vitro

28 November 2018

1 reference

12 December 2020

Human mast cells expressing recombinant proteinase 3 (PR3) as substrate for clinical testing for anti-neutrophil cytoplasmic antibodies (ANCA)

1 reference

12 December 2020

Interference of Wegener's granulomatosis autoantibodies with neutrophil Proteinase 3 activity

1 reference

12 December 2020

Relevance of classic anti-neutrophil cytoplasmic autoantibody (C-ANCA)-mediated inhibition of proteinase 3-alpha 1-antitrypsin complexation to disease activity in Wegener's granulomatosis

1 reference

12 December 2020

Cleavage and inactivation of human C1 inhibitor by the human leukocyte proteinase, proteinase 3

1 reference

12 December 2020

Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo

1 reference

12 December 2020

Epitopes on proteinase-3 recognized by antibodies from patients with Wegener's granulomatosis

1 reference

12 December 2020

Characterization of monoclonal antibodies to proteinase-3 and application in the study of epitopes for classical anti-neutrophil cytoplasm antibodies

1 reference

12 December 2020

Transforming growth factor-beta (TGF-beta) expression and interaction with proteinase 3 (PR3) in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis

1 reference

12 December 2020

Recombinant proteinase 3 (Wegener's antigen) expressed in Pichia pastoris is functionally active and is recognized by patient sera

1 reference

12 December 2020

Cationic proteins of neutrophil azurophilic granules: protein-protein interaction and blockade of NADPH oxidase activation

1 reference

12 December 2020

Pathogenesis of vasculitis

1 reference

12 December 2020

Identifiers

DOI

10.1186/AR99

1 reference

Dimensions Publication ID

5 July 2017

0 references

1 reference

5 July 2017

1 reference