(Q24807365)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Mutation analysis of the CHK2 gene in breast carcinoma and other cancers (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Gisli Ragnarsson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Jon T Bergthorsson

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

Bjarnveig I Sigbjornsdottir

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Chen Huiping

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Sigridur H Hafsteinsdottir

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Rosa B Barkardottir

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Adalgeir Arason

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Valgardur Egilsson

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

language of work or name

English

0 references

publication date

20 March 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

published in

Breast Cancer Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

R4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

9 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

Chromosome alterations and E-cadherin gene mutations in human lobular breast cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

Characterization of tumor-associated Chk2 mutations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.

30 May 2018

1 reference

Analysis of the CHK2 gene in lymphoid malignancies

21 January 2018

1 reference

Screening hCHK2 for Mutations

21 January 2018

1 reference

High prevalence of the 999del5 mutation in icelandic breast and ovarian cancer patients

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111029

Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53

28 November 2018

1 reference

Mutation analysis of the DNA-damage checkpoint gene CHK2 in myelodysplastic syndromes and acute myeloid leukemias

21 January 2018

1 reference

Chromosome 17q-linkage seems to be infrequent in Icelandic families at risk of breast cancer

21 January 2018

1 reference

Histological type-selective, tumor-predominant expression of a novel CHK1 isoform and infrequent in vivo somatic CHK2 mutation in small cell lung cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12052256

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12052256

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/BCR435

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12052256%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PubMed publication ID

12052256

1 reference