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The leucine rich region of DNA-PKcs contributes to its innate DNA affinity.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
1310895
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16340007%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
title
The leucine rich region of DNA-PKcs contributes to its innate DNA affinity
(English)
1 reference
stated in
Europe PubMed Central
PMCID
1310895
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16340007%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
author
Shikha Gupta
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
1310895
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16340007%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
author name string
Katheryn Meek
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
1310895
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16340007%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
language of work or name
English
0 references
publication date
9 December 2005
1 reference
stated in
Europe PubMed Central
PMCID
1310895
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16340007%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
published in
Nucleic Acids Research
1 reference
stated in
Europe PubMed Central
PMCID
1310895
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16340007%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
volume
33
1 reference
stated in
Europe PubMed Central
PMCID
1310895
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16340007%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
issue
22
1 reference
stated in
Europe PubMed Central
PMCID
1310895
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16340007%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
page(s)
6972-6981
1 reference
stated in
Europe PubMed Central
PMCID
1310895
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16340007%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
cites work
DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
7 April 2017
cDNA cloning, recombinant expression and characterization of polypetides with exceptional DNA affinity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
7 April 2017
DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
7 April 2017
Identification of DNA-PKcs phosphorylation sites in XRCC4 and effects of mutations at these sites on DNA end joining in a cell-free system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
7 April 2017
Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
7 April 2017
Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
7 April 2017
Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
7 April 2017
Geometry of a complex formed by double strand break repair proteins at a single DNA end: recruitment of DNA-PKcs induces inward translocation of Ku protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
7 April 2017
Binding of Ku and c-Abl at the kinase homology region of DNA-dependent protein kinase catalytic subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
7 April 2017
Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
7 April 2017
Autophosphorylation of DNA-dependent protein kinase regulates DNA end processing and may also alter double-strand break repair pathway choice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
DNA-PK-dependent phosphorylation of Ku70/80 is not required for non-homologous end joining.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
The DNA-dependent protein kinase: the director at the end.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
DNA-PKcs function regulated specifically by protein phosphatase 5
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
Repair of DNA double strand breaks by non-homologous end joining
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
The role of DNA dependent protein kinase in synapsis of DNA ends.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
Visualization of DNA-induced conformational changes in the DNA repair kinase DNA-PKcs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
Threonines 2638/2647 in DNA-PK are essential for cellular resistance to ionizing radiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
A single amino acid substitution in DNA-PKcs explains the novel phenotype of the CHO mutant, XR-C2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
Regulating the mammalian genome: the role of nuclear architecture
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
Identification of four highly conserved regions in DNA-PKcs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
Both V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
Analyses of TCRB rearrangements substantiate a profound deficit in recombination signal sequence joining in SCID foals: implications for the role of DNA-dependent protein kinase in V(D)J recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
Induction of apoptosis by overexpression of the DNA-binding and DNA-PK-activating protein C1D.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
DNA-dependent protein kinase: DNA binding and activation in the absence of Ku
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 September 2017
Three-dimensional structure and regulation of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
30 May 2018
Cell cycle responses of two X-ray sensitive mutants defective in DNA repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
30 May 2018
Non-homologous end joining requires that the DNA-PK complex undergo an autophosphorylation-dependent rearrangement at DNA ends.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 November 2018
DNA-PK phosphorylation sites in XRCC4 are not required for survival after radiation or for V(D)J recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 November 2018
Saccharomyces cerevisiae C1D is implicated in both non-homologous DNA end joining and homologous recombination.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1310895
retrieved
28 November 2018
Purification and characterization of the double-stranded DNA-activated protein kinase, DNA-PK, from human placenta
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16340007
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Photocross-linking of an oriented DNA repair complex. Ku bound at a single DNA end
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16340007
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/NAR/GKI990
1 reference
stated in
Europe PubMed Central
PMCID
1310895
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16340007%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
PMCID
1310895
1 reference
stated in
Europe PubMed Central
PMCID
1310895
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16340007%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
PubMed ID
16340007
1 reference
stated in
Europe PubMed Central
PMCID
1310895
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16340007%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 January 2020
ResearchGate publication ID
7429805
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