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Strict control of telomerase activation using Cre-mediated inversion.
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Europe PubMed Central
PMCID
1403769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16504006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
title
Strict control of telomerase activation using Cre-mediated inversion
(English)
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stated in
Europe PubMed Central
PMCID
1403769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16504006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author
Mark D. Ungrin
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1
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Europe PubMed Central
PMCID
1403769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16504006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
author name string
Lea Harrington
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2
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Europe PubMed Central
PMCID
1403769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16504006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
language of work or name
English
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publication date
20 February 2006
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Europe PubMed Central
PMCID
1403769
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retrieved
17 January 2020
published in
BMC Biotechnology
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Europe PubMed Central
PMCID
1403769
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16504006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
volume
6
1 reference
stated in
Europe PubMed Central
PMCID
1403769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16504006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
page(s)
10
1 reference
stated in
Europe PubMed Central
PMCID
1403769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16504006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
issue
1
0 references
exact match
https://scigraph.springernature.com/pub.10.1186/1472-6750-6-10
0 references
cites work
Human telomerase and its regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
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7 April 2017
Extension of life-span by introduction of telomerase into normal human cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
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7 April 2017
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
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7 April 2017
Human telomerase contains evolutionarily conserved catalytic and structural subunits
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
Targeted oncogene activation by site-specific recombination in transgenic mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
Reconstitution of human telomerase activity in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
The RNA component of human telomerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
Origin of Concatemeric T7DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
Telomeres shorten during ageing of human fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
Characteristics of a human cell line transformed by DNA from human adenovirus type 5
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
Telomerase catalytic subunit homologs from fission yeast and human
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
Reverse transcriptase motifs in the catalytic subunit of telomerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
Telomere length predicts replicative capacity of human fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
7 April 2017
Stepwise neoplastic transformation of a telomerase immortalized fibroblast cell line
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
A human beta-cell line for transplantation therapy to control type 1 diabetes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Cre-mediated reversible immortalization of human renal proximal tubular epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Establishment of an immortalized human-liver endothelial cell line with SV40T and hTERT.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Alterations in the p16(INK4a) and p53 tumor suppressor genes of hTERT-immortalized human fibroblasts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Regulated gene expression from adenovirus vectors: a systematic comparison of various inducible systems
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Molecular changes accompanying senescence and immortalization of cultured human mammary epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Reversible manipulation of telomerase expression and telomere length. Implications for the ionizing radiation response and replicative senescence of human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Comparison of human mammary epithelial cells immortalized by simian virus 40 T-Antigen or by the telomerase catalytic subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Quantitation of telomerase components and hTERT mRNA splicing patterns in immortal human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Clonal variation in phenotype and life span of human embryonic fibroblasts (MRC-5) transduced with the catalytic component of telomerase (hTERT).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Telomerase activity does not always imply telomere maintenance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Absence of cancer-associated changes in human fibroblasts immortalized with telomerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Telomerase activity, cell proliferation, and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Purification of telomerase from Euplotes aediculatus: requirement of a primer 3' overhang
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Targeted DNA recombination in vivo using an adenovirus carrying the cre recombinase gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Ecdysone-inducible gene expression in mammalian cells and transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Principle of marginotomy in template synthesis of polynucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Telomere reduction in human colorectal carcinoma and with ageing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 September 2017
Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
31 May 2018
Bicistronic vector for the creation of stable mammalian cell lines that predisposes all antibiotic-resistant cells to express recombinant protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
31 May 2018
Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 November 2018
Karyotype instability and anchorage-independent growth in telomerase-immortalized fibroblasts from two centenarian individuals.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 November 2018
Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 November 2018
Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 November 2018
Cre-loxP-mediated DNA flip-flop in mammalian cells leading to alternate expression of retrovirally transduced genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1403769
retrieved
28 November 2018
Linking-number changes in the DNA substrate during Cre-mediated loxP site-specific recombination
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16504006
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16504006
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transient expression of human telomerase extends the life span of normal human fibroblasts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16504006
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Reversible immortalization of human primary cells by lentivector-mediated transfer of specific genes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16504006
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1186/1472-6750-6-10
1 reference
stated in
Europe PubMed Central
PMCID
1403769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16504006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
Dimensions Publication ID
1052398368
0 references
PMCID
1403769
1 reference
stated in
Europe PubMed Central
PMCID
1403769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16504006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
PubMed ID
16504006
1 reference
stated in
Europe PubMed Central
PMCID
1403769
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16504006%20AND%20SRC:MED&resulttype=core&format=json
retrieved
17 January 2020
ResearchGate publication ID
7273667
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