(Q26770428)

Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment

volume

8

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issue

1

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page(s)

9-18

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cites work

1 reference

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Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors

7 April 2017

1 reference

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Open-label, clinical phase I studies of tasquinimod in patients with castration-resistant prostate cancer

7 April 2017

1 reference

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Identification of human S100A9 as a novel target for treatment of autoimmune disease via binding to quinoline-3-carboxamides

7 April 2017

1 reference

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The many roles of histone deacetylases in development and physiology: implications for disease and therapy

7 April 2017

1 reference

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Emerging therapies in castration resistant prostate cancer

7 April 2017

1 reference

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7 April 2017

Cancer statistics, 2014

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Hypoxia actively represses transcription by inducing negative cofactor 2 (Dr1/DrAP1) and blocking preinitiation complex assembly

7 April 2017

1 reference

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Abiraterone and increased survival in metastatic prostate cancer

7 April 2017

1 reference

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Assessment of the bone scan index in a randomized placebo-controlled trial of tasquinimod in men with metastatic castration-resistant prostate cancer (mCRPC).

7 April 2017

1 reference

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Enzalutamide in metastatic prostate cancer before chemotherapy

28 September 2017

1 reference

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Randomized, placebo-controlled, phase III trial of sunitinib plus prednisone versus prednisone alone in progressive, metastatic, castration-resistant prostate cancer.

28 September 2017

1 reference

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Long-term survival and biomarker correlates of tasquinimod efficacy in a multicenter randomized study of men with minimally symptomatic metastatic castration-resistant prostate cancer

28 September 2017

1 reference

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Randomized, double-blind, placebo-controlled phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic castration-resistant prostate cancer: CALGB 90401.

28 September 2017

1 reference

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Phase II randomized, double-blind, placebo-controlled study of tasquinimod in men with minimally symptomatic metastatic castrate-resistant prostate cancer

28 September 2017

1 reference

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The long and winding road for the development of tasquinimod as an oral second-generation quinoline-3-carboxamide antiangiogenic drug for the treatment of prostate cancer

28 September 2017

1 reference

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Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4

28 September 2017

1 reference

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Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group

28 September 2017

1 reference

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The quinoline-3-carboxamide anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and taxotere without effecting serum PSA directly in human xenografts

28 September 2017

1 reference

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Identification of ABR-215050 as lead second generation quinoline-3-carboxamide anti-angiogenic agent for the treatment of prostate cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707420

Molecular immunological approaches to biotherapy of human cancers--a review, hypothesis and implications

28 September 2017

1 reference

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Pathologic features of naturally occurring juvenile polyarteritis in beagle dogs

28 September 2017

1 reference

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The antitumor effects of the quinoline-3-carboxamide linomide on Dunning R-3327 rat prostatic cancers

28 September 2017

1 reference

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Loss of Histone Deacetylase 4 Causes Segregation Defects during Mitosis of p53-Deficient Human Tumor Cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707420

Nuclear accumulation of histone deacetylase 4 (HDAC4) coincides with the loss of androgen sensitivity in hormone refractory cancer of the prostate

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4707420

Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases

28 November 2018

1 reference

12 December 2020

Linomide in relapsing and secondary progressive MS: part I: trial design and clinical results. North American Linomide Investigators

1 reference

12 December 2020

Thrombospondin-1, vascular endothelial growth factor and fibroblast growth factor-2 are key functional regulators of angiogenesis in the prostate

1 reference

12 December 2020

Calcium-binding proteins S100A8 and S100A9 as novel diagnostic markers in human prostate cancer

1 reference

12 December 2020