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The role of SOX2 in small cell lung cancer, lung adenocarcinoma and squamous cell carcinoma of the lung
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PubMed
review article
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Europe PubMed Central
title
The role of SOX2 in small cell lung cancer, lung adenocarcinoma and squamous cell carcinoma of the lung
(English)
1 reference
stated in
PubMed
main subject
adenocarcinoma
1 reference
based on heuristic
inferred from title
squamous cell carcinoma of the lung
1 reference
based on heuristic
inferred from title
author name string
Karachaliou N
series ordinal
1
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stated in
PubMed
Rosell R
series ordinal
2
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stated in
PubMed
Viteri S
series ordinal
3
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stated in
PubMed
language of work or name
English
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stated in
PubMed
publication date
June 2013
1 reference
stated in
PubMed
published in
Translational lung cancer research
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stated in
PubMed
volume
2
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stated in
PubMed
issue
3
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stated in
PubMed
page(s)
172-9
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PubMed
cites work
Non-small cell lung cancer cells expressing CD44 are enriched for stem cell-like properties
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
7 April 2017
Evidence that SOX2 overexpression is oncogenic in the lung
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
7 April 2017
SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
7 April 2017
The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
7 April 2017
A distinct "side population" of cells with high drug efflux capacity in human tumor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
7 April 2017
Serological identification of embryonic neural proteins as highly immunogenic tumor antigens in small cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
7 April 2017
Cancer statistics, 2010
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
7 April 2017
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
7 April 2017
Vertebrate neurogenesis is counteracted by Sox1-3 activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
7 April 2017
Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
7 April 2017
Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
7 April 2017
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
7 April 2017
LKB1 modulates lung cancer differentiation and metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
25 May 2017
EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Increased Sox2 copy number in lung squamous cell carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Detection of MET and SOX2 amplification by quantitative real-time PCR in non-small cell lung carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Distinct functions of Sox2 control self-renewal and differentiation in the osteoblast lineage.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Sox2 protein expression is an independent poor prognostic indicator in stage I lung adenocarcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Expression of pluripotent stem cell reprogramming factors by prostate tumor initiating cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Back to basics: Sox genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Characterization of stem cell-like cancer cells in immune-competent mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
Expression of the SRY-related HMG box protein SOX2 in human gastric carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 September 2017
SOX2 in squamous cell carcinoma: amplifying a pleiotropic oncogene along carcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
31 May 2018
SOX2 is highly expressed in squamous cell carcinomas of the gastrointestinal tract
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
31 May 2018
Sox2 expression in pulmonary non-small cell and neuroendocrine carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
31 May 2018
SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 November 2018
The properties of tumor-initiating cells from a hepatocellular carcinoma patient's primary and recurrent tumor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 November 2018
Recurrent copy number gain of transcription factor SOX2 and corresponding high protein expression in oral squamous cell carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 November 2018
SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 November 2018
Sox17 and beta-catenin cooperate to regulate the transcription of endodermal genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367598
retrieved
28 November 2018
Small-cell lung cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25806230
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
SOX2 amplification is a common event in squamous cell carcinomas of different organ sites
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25806230
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3978/J.ISSN.2218-6751.2013.01.01
0 references
PMC publication ID
4367598
1 reference
stated in
PubMed
PubMed publication ID
25806230
1 reference
stated in
PubMed
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