(Q26823452)

English

Genetic and functional linkage between ADAMTS superfamily proteins and fibrillin-1: a novel mechanism influencing microfibril assembly and function

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Europe PubMed Central

Genetic and functional linkage between ADAMTS superfamily proteins and fibrillin-1: a novel mechanism influencing microfibril assembly and function (English)

1 reference

author name string

Dirk Hubmacher

1

1 reference

Suneel S. Apte

2

1 reference

language of work or name

1 reference

publication date

October 2011

1 reference

Cellular and Molecular Life Sciences

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68

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19

1 reference

3137-48

1 reference

ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts

1 reference

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Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation

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A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms

1 reference

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C-terminal ADAMTS-18 fragment induces oxidative platelet fragmentation, dissolves platelet aggregates, and protects against carotid artery occlusion and cerebral stroke

1 reference

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ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation

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O-fucosylation is required for ADAMTS13 secretion

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The molecular genetics of Marfan syndrome and related disorders

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Sequential deposition of latent TGF-beta binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts

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ADAMTS10 mutations in autosomal recessive Weill-Marchesani syndrome

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Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome

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In frame fibrillin-1 gene deletion in autosomal dominant Weill-Marchesani syndrome

1 reference

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Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein

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Regulation of limb patterning by extracellular microfibrils

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Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1

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Association of the small latent transforming growth factor-beta with an eight cysteine repeat of its binding protein LTBP-1

2 references

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7 April 2017

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A novel mutation of the fibrillin gene causing ectopia lentis

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7 April 2017

High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2)

1 reference

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Targeting of bone morphogenetic protein growth factor complexes to fibrillin

1 reference

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Interactions of fibrillin-1 with heparin/heparan sulfate, implications for microfibrillar assembly

1 reference

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7 April 2017

Clinical homogeneity and genetic heterogeneity in Weill-Marchesani syndrome

1 reference

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Making sense of latent TGFbeta activation

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7 April 2017

Role of the latent transforming growth factor beta binding protein 1 in fibrillin-containing microfibrils in bone cells in vitro and in vivo

1 reference

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7 April 2017

The revised Ghent nosology for the Marfan syndrome

1 reference

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7 April 2017

Angiotensin II blockade and aortic-root dilation in Marfan's syndrome

1 reference

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7 April 2017

O-fucosylation of thrombospondin type 1 repeats in ADAMTS-like-1/punctin-1 regulates secretion: implications for the ADAMTS superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

7 April 2017

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability

1 reference

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7 April 2017

Discovery and characterization of a novel, widely expressed metalloprotease, ADAMTS10, and its proteolytic activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

7 April 2017

A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motifs: the ADAMTS family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

7 April 2017

Ectopia lentis phenotypes and the FBN1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

7 April 2017

Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle glaucoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

7 April 2017

ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

7 April 2017

ADAMTS-like 2 (ADAMTSL2) is a secreted glycoprotein that is widely expressed during mouse embryogenesis and is regulated during skeletal myogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

7 April 2017

Carboxy-terminal conversion of profibrillin to fibrillin at a basic site by PACE/furin-like activity required for incorporation in the matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

7 April 2017

Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

7 April 2017

ADAMTSL4, a secreted glycoprotein widely distributed in the eye, binds fibrillin-1 microfibrils and accelerates microfibril biogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Molecular screening of ADAMTSL2 gene in 33 patients reveals the genetic heterogeneity of geleophysic dysplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Linkage of regulators of TGF-β activity in the fetal ovary to polycystic ovary syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

TB domain proteins: evolutionary insights into the multifaceted roles of fibrillins and LTBPs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

An ADAMTSL2 founder mutation causes Musladin-Lueke Syndrome, a heritable disorder of beagle dogs, featuring stiff skin and joint contractures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

In vivo studies of mutant fibrillin-1 microfibrils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Versican facilitates chondrocyte differentiation and regulates joint morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Mutations in fibrillin-1 cause congenital scleroderma: stiff skin syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Homozygous mutations in ADAMTS10 and ADAMTS17 cause lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Post-translational modification of thrombospondin type-1 repeats in ADAMTS-like 1/punctin-1 by C-mannosylation of tryptophan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Extracellular microfibrils: contextual platforms for TGFbeta and BMP signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Biogenesis and function of fibrillin assemblies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

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Genetic and molecular aspects of acromelic dysplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

A homozygous mutation in ADAMTSL4 causes autosomal-recessive isolated ectopia lentis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Fibrillin assembly requires fibronectin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Deficiency in microfibril-associated glycoprotein-1 leads to complex phenotypes in multiple organ systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Functional analysis of an ADAMTS10 signal peptide mutation in Weill-Marchesani syndrome demonstrates a long-range effect on secretion of the full-length enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Marfan syndrome: from molecular pathogenesis to clinical treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Fibrillins: from biogenesis of microfibrils to signaling functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Fibrillins 1 and 2 perform partially overlapping functions during aortic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

TGF-beta-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Latent TGF-beta binding proteins: extracellular matrix association and roles in TGF-beta activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Differential expression of fibrillin-3 adds to microfibril variety in human and avian, but not rodent, connective tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

TSRC1, a widely expressed gene containing seven thrombospondin type I repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

New insights into the assembly of extracellular microfibrils from the analysis of the fibrillin 1 mutation in the tight skin mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

The Marfan syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Lecticans: organizers of the brain extracellular matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

The Tight skin mouse: demonstration of mutant fibrillin-1 production and assembly into abnormal microfibrils.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Marfan syndrome: defective synthesis, secretion, and extracellular matrix formation of fibrillin by cultured dermal fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

Fibrillin-2 (FBN2) mutations result in the Marfan-like disorder, congenital contractural arachnodactyly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 September 2017

A novel ADAMTSL4 mutation in autosomal recessive ectopia lentis et pupillae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

31 May 2018

The characterisation of six ADAMTS proteases in the basal chordate Ciona intestinalis provides new insights into the vertebrate ADAMTS family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

31 May 2018

Extraction of extendable beaded structures and their identification as fibrillin-containing extracellular matrix microfibrils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

31 May 2018

Vitreous humor of chicken contains two fibrillar systems: an analysis of their structure.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0780-9

21 January 2018

Targetting of the gene encoding fibrillin-1 recapitulates the vascular aspect of Marfan syndrome.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0780-9

21 January 2018

Identification of a polycystic ovary syndrome susceptibility variant in fibrillin-3 and association with a metabolic phenotype.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0780-9

21 January 2018

Fibronectin and heparin binding domains of latent TGF-beta binding protein (LTBP)-4 mediate matrix targeting and cell adhesion.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0780-9

21 January 2018

Enhanced fibrillin-2 expression is a general feature of wound healing and sclerosis: potential alteration of cell attachment and storage of TGF-beta.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0780-9

21 January 2018

Versican-thrombospondin-1 binding in vitro and colocalization in microfibrils induced by inflammation on vascular smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0780-9

21 January 2018

Alternative splicing of papilin and the diversity of Drosophila extracellular matrix during embryonic morphogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0780-9

21 January 2018

Role of ADAMTSL4 mutations in FBN1 mutation-negative ectopia lentis patients.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0780-9

21 January 2018

Confirmation of ADAMTSL4 mutations for autosomal recessive isolated bilateral ectopia lentis.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0780-9

21 January 2018

A homozygous microdeletion within ADAMTSL4 in patients with isolated ectopia lentis: evidence of a founder mutation.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0780-9

21 January 2018

Fibrillin-1 microfibril deposition is dependent on fibronectin assembly

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0780-9

21 January 2018

The Ghent Marfan Trial--a randomized, double-blind placebo controlled trial with losartan in Marfan patients treated with β-blockers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 November 2018

Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 November 2018

Latent TGF-beta binding protein LTBP-1 contains three potential extracellular matrix interacting domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729447

28 November 2018

Geleophysic dysplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21858451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical localization of fibrillin in human ocular tissues. Relevance to the Marfan syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/21858451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and pathological observations concerning the aetiology of primary lens luxation in the dog

1 reference

https://pubmed.ncbi.nlm.nih.gov/21858451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21858451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AnADAMTS17Splice Donor Site Mutation in Dogs with Primary Lens Luxation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21858451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Versican interacts with fibrillin-1 and links extracellular microfibrils to other connective tissue networks

1 reference

https://pubmed.ncbi.nlm.nih.gov/21858451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomic analysis of fibrillin-rich microfibrils

1 reference

https://pubmed.ncbi.nlm.nih.gov/21858451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cutaneous microfibrillar apparatus contains latent transforming growth factor-beta binding protein-1 (LTBP-1) and is a repository for latent TGF-beta1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21858451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00018-011-0780-9

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Dimensions Publication ID

0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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