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Mucus penetrating nanoparticles: biophysical tool and method of drug and gene delivery
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scholarly article
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PubMed
title
Mucus penetrating nanoparticles: biophysical tool and method of drug and gene delivery
(English)
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stated in
PubMed
main subject
biophysics
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nanoparticle
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author name string
Ensign LM
series ordinal
1
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PubMed
Schneider C
series ordinal
2
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PubMed
Suk JS
series ordinal
3
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PubMed
Cone R
series ordinal
4
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PubMed
Hanes J
series ordinal
5
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PubMed
language of work or name
English
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stated in
PubMed
publication date
24 July 2012
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stated in
PubMed
published in
Advanced Materials
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stated in
PubMed
volume
24
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PubMed
issue
28
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PubMed
page(s)
3887-94
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PubMed
cites work
Micro- and macrorheology of mucus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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7 April 2017
Optical Measurements of Frequency-Dependent Linear Viscoelastic Moduli of Complex Fluids
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PubMed Central
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retrieved
7 April 2017
Mucoadhesive nanoparticles may disrupt the protective human mucus barrier by altering its microstructure
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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7 April 2017
Altering mucus rheology to"solidify" human mucus at the nanoscale
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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7 April 2017
Biodegradable mucus-penetrating nanoparticles composed of diblock copolymers of polyethylene glycol and poly(lactic-co-glycolic acid)
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
retrieved
28 September 2017
Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Non-degradative intracellular trafficking of highly compacted polymeric DNA nanoparticles
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PubMed Central
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28 September 2017
A poly(ethylene glycol)-based surfactant for formulation of drug-loaded mucus penetrating particles
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Highly compacted DNA nanoparticles with low MW PEG coatings: in vitro, ex vivo and in vivo evaluation.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
retrieved
28 September 2017
Drug carrier nanoparticles that penetrate human chronic rhinosinusitis mucus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Common gene therapy viral vectors do not efficiently penetrate sputum from cystic fibrosis patients
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteine
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Biodegradable nanoparticles composed entirely of safe materials that rapidly penetrate human mucus
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Long-term transgene expression in the central nervous system using DNA nanoparticles
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Mucins, mucus, and sputum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Extracellular barriers in respiratory gene therapy.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Gene transfer to the lung: lessons learned from more than 2 decades of CF gene therapy
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Barrier properties of mucus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Nanoparticles as protein and gene carriers to mucosal surfaces.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
MUC1 cell surface mucin is a critical element of the mucosal barrier to infection
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Evidence for airway surface dehydration as the initiating event in CF airway disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Real-time multiple-particle tracking: applications to drug and gene delivery
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Why consider vaginal drug administration?
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Microbicide efficacy and toxicity tests in a mouse model for vaginal transmission of Chlamydia trachomatis.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Polyanhydrides: an overview.
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PubMed Central
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28 September 2017
Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: the effect of mucus on particle adsorption and transport.
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PubMed Central
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28 September 2017
Diffusion of macromolecules and virus-like particles in human cervical mucus
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3710133
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28 September 2017
Surface modifications and molecular imprinting of polymers in medical and pharmaceutical applications
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28 September 2017
Molecular aspects of muco- and bioadhesion: tethered structures and site-specific surfaces
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PubMed Central
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28 September 2017
Antibody diffusion in human cervical mucus
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PubMed Central
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28 September 2017
Novel approaches to vaginal delivery and safety of microbicides: biopharmaceuticals, nanoparticles, and vaccines
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PubMed Central
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31 May 2018
Transfection of airway epithelium by stable PEGylated poly-L-lysine DNA nanoparticles in vivo
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31 May 2018
Variances in mucus architecture as a cause of cervical factor infertility.
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31 May 2018
Human cervical mucus and its interaction with sperm: a fine-structural view
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31 May 2018
Transport of metal oxide nanoparticles and single-walled carbon nanotubes in human mucus
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21 January 2018
Pegylated GL67 lipoplexes retain their gene transfection activity after exposure to components of CF mucus
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21 January 2018
Enhanced viscoelasticity of human cystic fibrotic sputum correlates with increasing microheterogeneity in particle transport.
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21 January 2018
Ultrastructure of the human periovulatory cervical mucus
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21 January 2018
Pluronic-based cationic block copolymer for forming pDNA polyplexes with enhanced cellular uptake and improved transfection efficiency
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21 January 2018
Uptake and release of budesonide from mucoadhesive, pH-sensitive copolymers and their application to nasal delivery
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/22988559
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cystic fibrosis
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22988559
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Human cervical mucus during the menstrual cycle and pregnancy in normal and pathological conditions
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22988559
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22988559
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1002/ADMA.201201800
0 references
PMC publication ID
3710133
1 reference
stated in
PubMed
PubMed publication ID
22988559
1 reference
stated in
PubMed
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