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The role of HMGB1 in the pathogenesis of inflammatory and autoimmune diseases
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scholarly article
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stated in
PubMed
title
The role of HMGB1 in the pathogenesis of inflammatory and autoimmune diseases
(English)
1 reference
stated in
PubMed
main subject
pathogenesis
1 reference
based on heuristic
inferred from title
inflammation
0 references
author name string
Melinda Magna
series ordinal
1
1 reference
stated in
Crossref
David Pisetsky
series ordinal
2
1 reference
stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
24 March 2014
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stated in
PubMed
published in
Molecular Medicine
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stated in
PubMed
volume
20
1 reference
stated in
PubMed
page(s)
138-46
1 reference
stated in
PubMed
copyright license
Creative Commons Attribution 4.0 International
start time
1 January 2014
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
cites work
High mobility group box protein 1 (HMGB1)-partner molecule complexes enhance cytokine production by signaling through the partner molecule receptor
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PubMed Central
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Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein
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7 April 2017
The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway
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PubMed Central
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The translocation of nuclear molecules during inflammation and cell death
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7 April 2017
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
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PubMed Central
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7 April 2017
HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences
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PubMed Central
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HMG-1 as a late mediator of endotoxin lethality in mice
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HMGB1 loves company
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PubMed Central
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High mobility group box 1 protein interacts with multiple Toll-like receptors
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PubMed Central
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7 April 2017
Requirement of HMGB1 and RAGE for the maturation of human plasmacytoid dendritic cells
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PubMed Central
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7 April 2017
The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system
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PubMed Central
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Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
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Nonresolving inflammation
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PubMed Central
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Netting neutrophils in autoimmune small-vessel vasculitis
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7 April 2017
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
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PubMed Central
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7 April 2017
An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies.
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PubMed Central
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28 September 2017
Protective effects of necrostatin-1 against concanavalin A-induced acute hepatic injury in mice
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28 September 2017
HMGB1 mediates splenomegaly and expansion of splenic CD11b+ Ly-6C(high) inflammatory monocytes in murine sepsis survivors.
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PubMed Central
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28 September 2017
Pyroptotic cells externalize eat-me and release find-me signals and are efficiently engulfed by macrophages.
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28 September 2017
The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis
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28 September 2017
TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis.
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28 September 2017
HMGB1 and leukocyte migration during trauma and sterile inflammation
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PubMed Central
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28 September 2017
Neutrophil extracellular traps: is immunity the second function of chromatin?
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28 September 2017
Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo.
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28 September 2017
Urine levels of HMGB1 in Systemic Lupus Erythematosus patients with and without renal manifestations
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PubMed Central
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28 September 2017
The origin and properties of extracellular DNA: from PAMP to DAMP.
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H1 and HMGB1: modulators of chromatin structure.
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PubMed Central
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28 September 2017
HMGB1: a multifunctional alarmin driving autoimmune and inflammatory disease
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity
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PubMed Central
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Neutrophil extracellular trap formation is associated with IL-1β and autophagy-related signaling in gout
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28 September 2017
Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1)
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
Caspase-1-induced pyroptotic cell death
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
Extracellular high-mobility group box 1 is increased in patients with Behçet's disease with intestinal involvement
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
HMGB1 is a therapeutic target for sterile inflammation and infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
HMGB1 release and redox regulates autophagy and apoptosis in cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
Autoimmunity and the clearance of dead cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
Inefficient clearance of dying cells in patients with SLE: anti-dsDNA autoantibodies, MFG-E8, HMGB-1 and other players.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
The role of HMGB1 in the pathogenesis of rheumatic disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
HMGB proteins: interactions with DNA and chromatin
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
Extracellular histones are major mediators of death in sepsis
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PubMed Central
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28 September 2017
Induction of inflammatory and immune responses by HMGB1-nucleosome complexes: implications for the pathogenesis of SLE
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
Autophagy regulates selective HMGB1 release in tumor cells that are destined to die.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
The extracellular release of HMGB1 during apoptotic cell death
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
HMGB1 is an endogenous immune adjuvant released by necrotic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 September 2017
IL-1β/HMGB1 complexes promote The PGE2 biosynthesis pathway in synovial fibroblasts
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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31 May 2018
Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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31 May 2018
Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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31 May 2018
HMGB1 levels are increased in patients with juvenile idiopathic arthritis, correlate with early onset of disease, and are independent of disease duration
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 November 2018
Immune complexes activate human endothelium involving the cell-signaling HMGB1-RAGE axis in the pathogenesis of lupus vasculitis.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 November 2018
Autoantibody induction by DNA-containing immune complexes requires HMGB1 with the TLR2/microRNA-155 pathway.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 November 2018
Elevated serum levels of high mobility group box protein 1 (HMGB1) in patients with ankylosing spondylitis and its association with disease activity and quality of life.
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PubMed Central
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28 November 2018
The effects of heparins on the liver: application of mechanistic serum biomarkers in a randomized study in healthy volunteers.
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28 November 2018
The extracellular release of DNA and HMGB1 from Jurkat T cells during in vitro necrotic cell death
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 November 2018
Effects of HMGB1 on in vitro responses of isolated muscle fibers and functional aspects in skeletal muscles of idiopathic inflammatory myopathies
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 November 2018
Oxidation of the alarmin high-mobility group box 1 protein (HMGB1) during apoptosis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 November 2018
The interaction of HMGB1 and linker histones occurs through their acidic and basic tails.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 November 2018
Increased expression of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in skin lesions of patients with lupus erythematosus
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966993
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28 November 2018
Down-regulation of the aberrant expression of the inflammation mediator high mobility group box chromosomal protein 1 in muscle tissue of patients with polymyositis and dermatomyositis treated with corticosteroids
1 reference
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PubMed Central
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28 November 2018
High mobility group box chromosomal protein 1, a DNA binding cytokine, induces arthritis
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PubMed Central
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28 November 2018
High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine
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Crossref
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31 March 2020
Successful treatment of collagen-induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity
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Crossref
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31 March 2020
Increased extracellular levels of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in minor salivary glands of patients with Sjögren's syndrome
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Crossref
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31 March 2020
Circulating platelets as a source of the damage-associated molecular pattern HMGB1 in patients with systemic sclerosis
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Crossref
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https://api.crossref.org/works/10.2119%2FMOLMED.2013.00164
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31 March 2020
High mobility group box1 (HMGB1) in relation to cutaneous inflammation in systemic lupus erythematosus (SLE)
1 reference
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Crossref
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31 March 2020
ROS eliminate danger
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Crossref
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31 March 2020
Identifiers
DOI
10.2119/MOLMED.2013.00164
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1536763
Dimensions Publication ID
1068965646
1 reference
stated in
SciGraph
retrieved
9 September 2019
reference URL
https://scigraph.springernature.com/pub.10.2119/molmed.2013.00164
OpenCitations bibliographic resource ID
1536763
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1536763
PMC publication ID
3966993
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1536763
PubMed publication ID
24531836
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1536763
ResearchGate publication ID
260211461
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