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The mTOR pathway and integrating immune regulation
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PubMed
title
The mTOR pathway and integrating immune regulation
(English)
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stated in
PubMed
author name string
Stephen P. Cobbold
series ordinal
1
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Crossref
language of work or name
English
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stated in
PubMed
publication date
December 2013
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stated in
PubMed
published in
Immunology
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stated in
PubMed
volume
140
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PubMed
issue
4
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PubMed
page(s)
391-8
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PubMed
cites work
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Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5
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Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
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mTOR regulates memory CD8 T-cell differentiation
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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
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Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells
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Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak
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The extracellular versus intracellular mechanisms of inhibition of TCR-triggered activation in thymocytes by adenosine under conditions of inhibited adenosine deaminase
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mTOR signaling at a glance
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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
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On respiratory impairment in cancer cells
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mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function
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Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
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28 September 2017
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28 September 2017
IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan
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28 September 2017
TIM-3 regulates innate immune cells to induce fetomaternal tolerance.
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28 September 2017
Tryptophan hydroxylase-1 regulates immune tolerance and inflammation
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28 September 2017
Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
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28 September 2017
Biomarkers of transplantation tolerance: more hopeful than helpful?
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28 September 2017
Sustained suppression by Foxp3+ regulatory T cells is vital for infectious transplantation tolerance
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28 September 2017
HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
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28 September 2017
Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production.
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28 September 2017
Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.
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28 September 2017
An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness.
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28 September 2017
mTOR signalling and metabolic regulation of T cell differentiation
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28 September 2017
Ecto-5'-nucleotidase (CD73) attenuates allograft airway rejection through adenosine 2A receptor stimulation.
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CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice
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The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.
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T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.
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28 September 2017
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells
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28 September 2017
Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells
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28 September 2017
Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway
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28 September 2017
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28 September 2017
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GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.
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based on heuristic
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A role for mammalian target of rapamycin in regulating T cell activation versus anergy
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Identifiers
DOI
10.1111/IMM.12162
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4891556
Fatcat ID
release_ofpltaxxkvdetlk4rigm5svtcy
0 references
OpenCitations bibliographic resource ID
4891556
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4891556
PMC publication ID
3839643
1 reference
stated in
PubMed
PubMed publication ID
23952610
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4891556
ResearchGate publication ID
255972503
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