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Interplay between lipids and branched-chain amino acids in development of insulin resistance
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PubMed
title
Interplay between lipids and branched-chain amino acids in development of insulin resistance
(English)
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PubMed
main subject
preproinsulin
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based on heuristic
inferred from title
lipid
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insulin resistance
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inferred from title
author name string
Christopher B. Newgard
series ordinal
1
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Crossref
language of work or name
English
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PubMed
publication date
2 May 2012
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PubMed
published in
Cell Metabolism
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PubMed
volume
15
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PubMed
issue
5
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PubMed
page(s)
606-14
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PubMed
cites work
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GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo.
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7 April 2017
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
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Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle
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Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss
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Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss
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28 September 2017
Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways
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Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle
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28 September 2017
Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels.
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28 September 2017
Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men
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28 September 2017
Metabolomics applied to diabetes research: moving from information to knowledge
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28 September 2017
Fermentative production of branched chain amino acids: a focus on metabolic engineering
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28 September 2017
Regulation of glutamate metabolism and insulin secretion by glutamate dehydrogenase in hypoglycemic children
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Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women
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28 September 2017
Leucine supplementation of drinking water does not alter susceptibility to diet-induced obesity in mice
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28 September 2017
Amino acid regulation of TOR complex 1.
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28 September 2017
Comparison of strategies for sustaining weight loss: the weight loss maintenance randomized controlled trial
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28 September 2017
Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes
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28 September 2017
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
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28 September 2017
Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism.
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28 September 2017
Disordered lipid metabolism and the pathogenesis of insulin resistance
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28 September 2017
Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.
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28 September 2017
Branched-chain amino acid catabolism in exercise and liver disease
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28 September 2017
Branched-chain amino acids and brain function
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28 September 2017
Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue
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28 September 2017
Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells
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28 September 2017
Splanchnic glucose and amino acid metabolism in obesity
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28 September 2017
Fuel selection in human skeletal muscle in insulin resistance: a reexamination
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28 September 2017
Lipid rather than glucose metabolism is implicated in altered insulin secretion caused by oleate in INS-1 cells
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28 September 2017
Regulatory interactions between lipids and carbohydrates: the glucose fatty acid cycle after 35 years.
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28 September 2017
Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes
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28 September 2017
The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation
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28 September 2017
Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat.
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28 September 2017
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31 May 2018
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31 May 2018
Increased lipogenic capacity of the islets of obese rats: a role in the pathogenesis of NIDDM.
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28 November 2018
Insulin resistance of protein metabolism in type 2 diabetes
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28 November 2018
Determinants of whole-body protein metabolism in subjects with and without type 2 diabetes
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28 November 2018
Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability.
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28 November 2018
Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.
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28 November 2018
A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle.
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28 November 2018
Regulation of leucine-stimulated insulin secretion and glutamine metabolism in isolated rat islets
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28 November 2018
Mechanism of amino acid-induced skeletal muscle insulin resistance in humans
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28 November 2018
Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes
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28 November 2018
Plasma Amino Acid Levels and Insulin Secretion in Obesity
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28 November 2018
Diabetes: treatment of type 2 diabetes mellitus with bariatric surgery
1 reference
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanisms
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22560213
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CMET.2012.01.024
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
200122
OpenCitations bibliographic resource ID
200122
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
200122
PMC publication ID
3695706
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
200122
PubMed publication ID
22560213
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
200122
ResearchGate publication ID
224912760
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