(Q26852473)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23706667%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Cytosolic sensing of viruses (English)

2 references

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1 March 2020

0 references

3

1 reference

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1 March 2020

author name string

Delphine Goubau

series ordinal

1

2 references

Crossref

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1 March 2020

Safia Deddouche

series ordinal

2

2 references

Crossref

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1 March 2020

language of work or name

1 reference

1 May 2013

1 reference

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1 March 2020

2 references

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1 March 2020

volume

38

2 references

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1 March 2020

issue

5

2 references

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1 March 2020

page(s)

855-869

1 reference

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Ankrd17 positively regulates RIG-I-like receptor (RLR)-mediated immune signaling

1 March 2020

cites work

1 reference

12 December 2020

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

1 reference

12 December 2020

Intrinsic antiviral immunity

1 reference

12 December 2020

A diverse range of gene products are effectors of the type I interferon antiviral response

1 reference

12 December 2020

DNA-PK is a DNA sensor for IRF-3-dependent innate immunity.

1 reference

12 December 2020

Paramyxovirus V proteins disrupt the fold of the RNA sensor MDA5 to inhibit antiviral signaling

1 reference

12 December 2020

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

1 reference

12 December 2020

Influenza virus protein PB1-F2 inhibits the induction of type I interferon by binding to MAVS and decreasing mitochondrial membrane potential

1 reference

12 December 2020

Human DEAD box helicase 3 couples IκB kinase ε to interferon regulatory factor 3 activation.

1 reference

12 December 2020

Dengue virus targets the adaptor protein MITA to subvert host innate immunity

1 reference

12 December 2020

The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.

1 reference

12 December 2020

Influenza A virus polymerase inhibits type I interferon induction by binding to interferon beta promoter stimulator 1.

1 reference

12 December 2020

Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

1 reference

12 December 2020

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

1 reference

12 December 2020

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

1 reference

12 December 2020

Structural Insights into RNA Recognition by RIG-I

1 reference

12 December 2020

IFI16 is an innate immune sensor for intracellular DNA

1 reference

12 December 2020

Unpaired 5' ppp-nucleotides, as found in arenavirus double-stranded RNA panhandles, are not recognized by RIG-I

1 reference

12 December 2020

Genome trimming by Borna disease viruses: viral replication control or escape from cellular surveillance?

1 reference

12 December 2020

MDA-5 is cleaved in poliovirus-infected cells

1 reference

12 December 2020

Evolutionary conflicts between viruses and restriction factors shape immunity

1 reference

12 December 2020

The thermodynamic basis for viral RNA detection by the RIG-I innate immune sensor

1 reference

12 December 2020

Short double-stranded RNAs with an overhanging 5' ppp-nucleotide, as found in arenavirus genomes, act as RIG-I decoys

1 reference

12 December 2020

MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP.

1 reference

12 December 2020

ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses

1 reference

12 December 2020

Cell type-specific involvement of RIG-I in antiviral response

1 reference

12 December 2020

Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING.

1 reference

12 December 2020

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

1 reference

12 December 2020

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

1 reference

12 December 2020

Pattern recognition receptors and inflammation

1 reference

12 December 2020

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential

1 reference

12 December 2020

NLRX1/NOD5 deficiency does not affect MAVS signalling

1 reference

12 December 2020

Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation

1 reference

12 December 2020

The 5' ends of Hantaan virus (Bunyaviridae) RNAs suggest a prime-and-realign mechanism for the initiation of RNA synthesis

1 reference

12 December 2020

Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease

1 reference

12 December 2020

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

1 reference

12 December 2020

USP4 positively regulates RIG-I-mediated antiviral response through deubiquitination and stabilization of RIG-I.

1 reference

12 December 2020

Induction and evasion of type I interferon responses by influenza viruses

1 reference

12 December 2020

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

1 reference

12 December 2020

DENV inhibits type I IFN production in infected cells by cleaving human STING

1 reference

12 December 2020

Rig-I-/- mice develop colitis associated with downregulation of G alpha i2.

1 reference

12 December 2020

Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response

1 reference

12 December 2020

The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling

1 reference

12 December 2020

Immune sensing of DNA

1 reference

12 December 2020

Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach

1 reference

12 December 2020

Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

1 reference

12 December 2020

Nuclear IFI16 induction of IRF-3 signaling during herpesviral infection and degradation of IFI16 by the viral ICP0 protein

1 reference

12 December 2020

Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling

1 reference

12 December 2020

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

1 reference

12 December 2020

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

1 reference

12 December 2020

The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy

1 reference

12 December 2020

Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein.

1 reference

12 December 2020

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

1 reference

12 December 2020

The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon

1 reference

12 December 2020

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation

1 reference

12 December 2020

5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential

1 reference

12 December 2020

RAVER1 is a coactivator of MDA5-mediated cellular antiviral response.

1 reference

12 December 2020

Active transposition in genomes

1 reference

12 December 2020

Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis

1 reference

12 December 2020

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

1 reference

12 December 2020

RIG-I detects viral genomic RNA during negative-strand RNA virus infection

1 reference

12 December 2020

Peroxisomes are signaling platforms for antiviral innate immunity

1 reference

12 December 2020

Activation of STAT6 by STING is critical for antiviral innate immunity

1 reference

12 December 2020

DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling

1 reference

12 December 2020

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

1 reference

12 December 2020

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

1 reference

12 December 2020

The leader proteinase of foot-and-mouth disease virus negatively regulates the type I interferon pathway by acting as a viral deubiquitinase

1 reference

12 December 2020

Cyclic di-GMP sensing via the innate immune signaling protein STING

1 reference

12 December 2020

Acetylation modulates cellular distribution and DNA sensing ability of interferon-inducible protein IFI16.

1 reference

12 December 2020

Phosphorylation-mediated negative regulation of RIG-I antiviral activity

1 reference

12 December 2020

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

1 reference

12 December 2020

The structural basis for the sensing and binding of cyclic di-GMP by STING

1 reference

12 December 2020

Innate immune responses in human monocyte-derived dendritic cells are highly dependent on the size and the 5' phosphorylation of RNA molecules

1 reference

12 December 2020

Visualisation of direct interaction of MDA5 and the dsRNA replicative intermediate form of positive strand RNA viruses

1 reference

12 December 2020

RNA sensor-induced type I IFN prevents diabetes caused by a β cell-tropic virus in mice

1 reference

12 December 2020

NLRC5 deficiency does not influence cytokine induction by virus and bacteria infections.

1 reference

12 December 2020

Cutting edge: Ku70 is a novel cytosolic DNA sensor that induces type III rather than type I IFN.

1 reference

12 December 2020

Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor RIG-I

1 reference

12 December 2020

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids

1 reference

12 December 2020

Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5

1 reference

12 December 2020

DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB

1 reference

12 December 2020

Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling

1 reference

12 December 2020

The C proteins of human parainfluenza virus type 1 limit double-stranded RNA accumulation that would otherwise trigger activation of MDA5 and protein kinase R

1 reference

12 December 2020

MDA-5 recognition of a murine norovirus

1 reference

12 December 2020

TRIM32 protein modulates type I interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination

1 reference

12 December 2020

NLRX1 does not inhibit MAVS-dependent antiviral signalling.

1 reference

12 December 2020

The mitochondrial targeting chaperone 14-3-3ε regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity.

1 reference

12 December 2020

Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells

1 reference

12 December 2020

Mitochondrial membrane potential is required for MAVS-mediated antiviral signaling

1 reference

12 December 2020

Structural basis of RNA recognition and activation by innate immune receptor RIG-I

1 reference

12 December 2020

MDA5 detects the double-stranded RNA replicative form in picornavirus-infected cells.

1 reference

12 December 2020

Ndfip1 negatively regulates RIG-I-dependent immune signaling by enhancing E3 ligase Smurf1-mediated MAVS degradation

1 reference

12 December 2020

Structure and Functional Characterization of the RNA-Binding Element of the NLRX1 Innate Immune Modulator

1 reference

12 December 2020

Extensive evolutionary and functional diversity among mammalian AIM2-like receptors

1 reference

12 December 2020

Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus

1 reference

12 December 2020

Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses

1 reference

12 December 2020

The double-stranded RNA-binding protein PACT functions as a cellular activator of RIG-I to facilitate innate antiviral response

1 reference

12 December 2020

Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells.

1 reference

12 December 2020

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

1 reference

12 December 2020

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

1 reference

12 December 2020

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

1 reference

12 December 2020

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

1 reference

12 December 2020

Regulation of RLR-mediated innate immune signaling--it is all about keeping the balance

1 reference

12 December 2020

DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.

1 reference

12 December 2020

Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition

1 reference

12 December 2020

Activation of innate immune antiviral responses by Nod2

1 reference

12 December 2020

Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I).

1 reference

12 December 2020

Inhibition of RIG-I-mediated signaling by Kaposi's sarcoma-associated herpesvirus-encoded deubiquitinase ORF64.

1 reference

12 December 2020

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

1 reference

12 December 2020

Arterivirus and nairovirus ovarian tumor domain-containing Deubiquitinases target activated RIG-I to control innate immune signaling

1 reference

12 December 2020

Focal adhesion kinase is a component of antiviral RIG-I-like receptor signaling

1 reference

12 December 2020

MDA5 assembles into a polar helical filament on dsRNA.

1 reference

12 December 2020

1 reference

12 December 2020

Recent advances in understanding viral evasion of type I interferon

1 reference

12 December 2020

MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA

1 reference

12 December 2020

DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells

1 reference

12 December 2020

Induction of type I IFNs by intracellular DNA-sensing pathways

1 reference

12 December 2020

Tetraspanin 6 (TSPAN6) negatively regulates retinoic acid-inducible gene I-like receptor-mediated immune signaling in a ubiquitination-dependent manner

1 reference

12 December 2020

Activation of RIG-I-like receptor signal transduction

1 reference

12 December 2020

Murine Coronavirus Mouse Hepatitis Virus Is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/Microglia

1 reference

12 December 2020

Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways

1 reference

12 December 2020

Kaposi's sarcoma-associated herpesvirus viral protein kinase interacts with RNA helicase a and regulates host gene expression

1 reference

12 December 2020

RIG-I is cleaved during picornavirus infection

1 reference

12 December 2020

Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity

1 reference

12 December 2020

Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria

1 reference

12 December 2020

Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding

1 reference

12 December 2020

The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein

1 reference

12 December 2020

Duplex RNA activated ATPases (DRAs): platforms for RNA sensing, signaling and processing

1 reference

12 December 2020

Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

1 reference

12 December 2020

Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses

1 reference

12 December 2020

Regulation of the innate immune response by threonine-phosphatase of Eyes absent

1 reference

12 December 2020

RIG-I plays a critical role in negatively regulating granulocytic proliferation

1 reference

12 December 2020

Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila

1 reference

12 December 2020

STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway

1 reference

12 December 2020

DHX9 pairs with IPS-1 to sense double-stranded RNA in myeloid dendritic cells

1 reference

12 December 2020

Old World hantaviruses do not produce detectable amounts of dsRNA in infected cells and the 5' termini of their genomic RNAs are monophosphorylated.

1 reference

12 December 2020

Molecular mechanisms of viral inhibitors of RIG-I-like receptors

1 reference

12 December 2020

STING manifests self DNA-dependent inflammatory disease

1 reference

12 December 2020

Hepatitis B virus regulatory HBx protein binds to adaptor protein IPS-1 and inhibits the activation of beta interferon

1 reference

12 December 2020

NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways

1 reference

12 December 2020

NLRX1 has a tail to tell

1 reference

12 December 2020

Type I interferonopathies: a novel set of inborn errors of immunity

1 reference

12 December 2020

The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides

1 reference

12 December 2020

Immunology in the clinic review series; focus on type 1 diabetes and viruses: the innate immune response to enteroviruses and its possible role in regulating type 1 diabetes.

1 reference

12 December 2020

The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response

1 reference

12 December 2020

Structural insights into RNA recognition and activation of RIG-I-like receptors

1 reference

12 December 2020

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

1 reference

12 December 2020

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

1 reference

12 December 2020

Activation of MDA5 requires higher-order RNA structures generated during virus infection

1 reference

12 December 2020

Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1.

1 reference

12 December 2020

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

1 reference

12 December 2020

Mitochondria in innate immunity

1 reference

12 December 2020

Kinetic mechanism for viral dsRNA length discrimination by MDA5 filaments

1 reference

12 December 2020

The regulation of type I interferon production by paramyxoviruses.

1 reference

12 December 2020

5'-Triphosphate RNA is the ligand for RIG-I

1 reference

12 December 2020

NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways

1 reference

12 December 2020

MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals

1 reference

12 December 2020

Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation

1 reference

12 December 2020

SUMOylation of RIG-I positively regulates the type I interferon signaling

1 reference

12 December 2020

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA

1 reference

12 December 2020

The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway

1 reference

12 December 2020

IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling

1 reference

12 December 2020

The RIG-I-like receptor LGP2 controls CD8(+) T cell survival and fitness

1 reference

12 December 2020

STING is a direct innate immune sensor of cyclic di-GMP

1 reference

12 December 2020

Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

1 reference

12 December 2020

Small self-RNA generated by RNase L amplifies antiviral innate immunity

1 reference

12 December 2020

Virus interference. I. The interferon

1 reference

12 December 2020

Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production

1 reference

12 December 2020

The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling

1 reference

12 December 2020

Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity

1 reference

12 December 2020

DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

1 reference

12 December 2020

The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA

1 reference

12 December 2020

Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling

1 reference

12 December 2020

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

1 reference

12 December 2020

Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

1 reference

12 December 2020

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

1 reference

12 December 2020

Ubiquitin-mediated modulation of the cytoplasmic viral RNA sensor RIG-I.

1 reference

12 December 2020

MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response

1 reference

12 December 2020

Establishment and Maintenance of the Innate Antiviral Response to West Nile Virus Involves both RIG-I and MDA5 Signaling through IPS-1

1 reference

12 December 2020

10.1016/J.IMMUNI.2013.05.007

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

581332

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1 March 2020

581332

1 reference

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Consolidated OpenCitations Corpus – April 2017

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2 references

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