(Q26862195)

title

The perfect storm: HLA antibodies, complement, FcγRs, and endothelium in transplant rejection (English)

1 reference

0 references

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801125%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Nicole M Valenzuela

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801125%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Elaine F Reed

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801125%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

language of work or name

1 reference

May 2015

1 reference

Trends in Molecular Medicine

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801125%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

21

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801125%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

319-329

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801125%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

5

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801125%20AND%20SRC:MED&resulttype=core&format=json

Complement regulation of T-cell alloimmunity

7 June 2020

cites work

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21 March 2017

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21 March 2017

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Detection of C3d-binding donor-specific anti-HLA antibodies at diagnosis of humoral rejection predicts renal graft loss.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Alloantibody and complement promote T cell-mediated cardiac allograft vasculopathy through noncanonical nuclear factor-κB signaling in endothelial cells.

28 September 2017

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Immune cell-derived C3a and C5a costimulate human T cell alloimmunity.

28 September 2017

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T cell-independent B cell activation induces immunosuppressive sialylated IgG antibodies.

28 September 2017

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Anti-donor HLA class I antibodies: pathways to endothelial cell activation and cell-mediated allograft rejection

28 September 2017

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De novo donor-specific HLA antibodies decrease patient and graft survival in liver transplant recipients

28 September 2017

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HLA class I antibodies trigger increased adherence of monocytes to endothelial cells by eliciting an increase in endothelial P-selectin and, depending on subclass, by engaging FcγRs

28 September 2017

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Rapamycin-treated human endothelial cells preferentially activate allogeneic regulatory T cells

28 September 2017

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Molecular diagnosis of antibody-mediated rejection in human kidney transplants

28 September 2017

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Incidence and impact of de novo donor-specific alloantibody in primary renal allografts

28 September 2017

1 reference

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Pathologic findings in lung allografts with anti-HLA antibodies

28 September 2017

1 reference

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A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer

28 September 2017

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Pathology of C4d-negative antibody-mediated rejection in renal allografts

28 September 2017

1 reference

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Blockade of p-selectin is sufficient to reduce MHC I antibody-elicited monocyte recruitment in vitro and in vivo

28 September 2017

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Antibody-mediated vascular rejection of kidney allografts: a population-based study

28 September 2017

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The role of complement in antibody-mediated rejection in kidney transplantation

28 September 2017

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The immunoglobulin, IgG Fc receptor and complement triangle in autoimmune diseases

28 September 2017

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Morphologic and immunohistochemical findings in antibody-mediated rejection of the cardiac allograft

28 September 2017

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The fate of renal allografts hinges on responses of the microvascular endothelium

28 September 2017

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Properties of mouse and human IgG receptors and their contribution to disease models

28 September 2017

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Mouse model recapitulating human Fcγ receptor structural and functional diversity

28 September 2017

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A longitudinal study of the course of asymptomatic antibody-mediated rejection in heart transplantation.

28 September 2017

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A novel pathway of chronic allograft rejection mediated by NK cells and alloantibody

28 September 2017

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Antibody ligation of human leukocyte antigen class I molecules stimulates migration and proliferation of smooth muscle cells in a focal adhesion kinase-dependent manner

28 September 2017

1 reference

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Impact of differential glycosylation on IgG activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Human endothelial cells generate Th17 and regulatory T cells under inflammatory conditions.

28 September 2017

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The role of differential IgG glycosylation in the interaction of antibodies with FcγRs in vivo

28 September 2017

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Pretransplant predictors of survival after intestinal transplantation: analysis of a single-center experience of more than 100 transplants

28 September 2017

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28 September 2017

The IMGT/HLA database

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New insights of an old defense system: structure, function, and clinical relevance of the complement system

28 September 2017

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Prevalence of HLA antibodies in remotely transfused or alloexposed volunteer blood donors

28 September 2017

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Complement independent antibody-mediated endarteritis and transplant arteriopathy in mice

28 September 2017

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Dynamics of the interaction of human IgG subtype immune complexes with cells expressing R and H allelic forms of a low-affinity Fc gamma receptor CD32A.

28 September 2017

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Asymptomatic antibody-mediated rejection after heart transplantation predicts poor outcomes.

28 September 2017

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Mechanisms of complement activation, C4d deposition, and their contribution to the pathogenesis of antibody-mediated rejection

28 September 2017

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Glycosylation as a strategy to improve antibody-based therapeutics

28 September 2017

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Regulated glycosylation patterns of IgG during alloimmune responses against human platelet antigens

28 September 2017

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New concepts of complement in allorecognition and graft rejection

28 September 2017

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Evolving functions of endothelial cells in inflammation

28 September 2017

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Antiendothelial cell antibodies mediate enhanced leukocyte adhesion to cytokine-activated endothelial cells through a novel mechanism requiring cooperation between Fc{gamma}RIIa and CXCR1/2.

28 September 2017

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Antibody to human leukocyte antigen triggers endothelial exocytosis

28 September 2017

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Macrophages induce the inflammatory response in the pulmonary Arthus reaction through G alpha i2 activation that controls C5aR and Fc receptor cooperation.

28 September 2017

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Normal human kidney HLA-DR-expressing renal microvascular endothelial cells: characterization, isolation, and regulation of MHC class II expression

28 September 2017

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C5a anaphylatoxin is a major regulator of activating versus inhibitory FcgammaRs in immune complex-induced lung disease

28 September 2017

1 reference

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28 September 2017

IgG4 breaking the rules

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Recognition sites on human IgG for Fc gamma receptors: the role of glycosylation

28 September 2017

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H-2 S region determined polymorphic variants of the C4, Slp, C2, and B complement proteins: A compilation

28 September 2017

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Segmental flexibility and complement fixation of genetically engineered chimeric human, rabbit and mouse antibodies

28 September 2017

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Everolimus inhibits anti-HLA I antibody-mediated endothelial cell signaling, migration and proliferation more potently than sirolimus.

28 September 2017

1 reference

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Molecular imaging of innate immune cell function in transplant rejection

31 May 2018

1 reference

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Phosphoinositide 3-kinases gamma and delta, linkers of coordinate C5a receptor-Fcgamma receptor activation and immune complex-induced inflammation

31 May 2018

1 reference

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Cell-derived anaphylatoxins as key mediators of antibody-dependent type II autoimmunity in mice

31 May 2018

1 reference

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The effect of antibody isotype and antigenic epitope density on the complement-fixing activity of immune complexes: a systematic study using chimaeric anti-NIP antibodies with human Fc regions

31 May 2018

1 reference

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Endothelial gene expression in kidney transplants with alloantibody indicates antibody-mediated damage despite lack of C4d staining.

31 May 2018

1 reference

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Eculizumab and Splenectomy as Salvage Therapy for Severe Antibody-Mediated Rejection After HLA–Incompatible Kidney Transplantation

31 May 2018

1 reference

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Post-transplant development of C1q-positive HLA antibodies and kidney graft survival.

28 November 2018

1 reference

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Late antibody-mediated rejection in renal allografts: outcome after conventional and novel therapies.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Screening for HLA antibodies in plateletpheresis donors with a history of transfusion or pregnancy.

28 November 2018

1 reference

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Banff 2013 meeting report: inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesions

28 November 2018

1 reference

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The 2013 International Society for Heart and Lung Transplantation Working Formulation for the standardization of nomenclature in the pathologic diagnosis of antibody-mediated rejection in heart transplantation.

28 November 2018

1 reference

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Microarray diagnosis of antibody-mediated rejection in kidney transplant biopsies: an international prospective study (INTERCOM).

28 November 2018

1 reference

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Complement-binding anti-HLA antibodies and kidney-allograft survival

28 November 2018

1 reference

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Clinical relevance of pretransplant anti-HLA donor-specific antibodies: does C1q-fixation matter?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Pathologic classification of antibody-mediated rejection correlates with donor-specific antibodies and endothelial cell activation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

The role of immunoglobulin-G subclasses and C1q in de novo HLA-DQ donor-specific antibody kidney transplantation outcomes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Systematic comparison of four cell- and Luminex-based methods for assessment of complement-activating HLA antibodies

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Antibody-mediated allograft rejection: morphologic spectrum and serologic correlations in surveillance and for cause biopsies

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Donor-specific human leukocyte antigen antibodies of the immunoglobulin G3 subclass are associated with chronic rejection and graft loss after liver transplantation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Tolerance induction with T cell-dependent protein antigens induces regulatory sialylated IgGs.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Evolution and clinical pathologic correlations of de novo donor-specific HLA antibody post kidney transplant.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Interpreting NK cell transcripts versus T cell transcripts in renal transplant biopsies.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Novel C1q assay reveals a clinically relevant subset of human leukocyte antigen antibodies independent of immunoglobulin G strength on single antigen beads.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Endothelitis in cardiac allograft biopsy specimens: Possible relationship to antibody-mediated rejection

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Clinical usefulness of a novel C1q assay to detect immunoglobulin G antibodies capable of fixing complement in sensitized pediatric heart transplant patients.

28 November 2018

1 reference

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NK cell transcripts and NK cells in kidney biopsies from patients with donor-specific antibodies: evidence for NK cell involvement in antibody-mediated rejection.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Glycan profiling of anti-citrullinated protein antibodies isolated from human serum and synovial fluid

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

C3 polymorphisms and allograft outcome in renal transplantation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Association of Fc gamma receptor IIA polymorphisms with acute renal-allograft rejection.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Non-complement- and complement-activating antibodies synergize to cause rejection of cardiac allografts.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424065

Human Leukocyte Antigen-Specific Antibodies and Gamma-Interferon Stimulate Human Microvascular and Glomerular Endothelial Cells to Produce Complement Factor C4

28 November 2018

1 reference

12 December 2020

Preformed complement-activating low-level donor-specific antibody predicts early antibody-mediated rejection in renal allografts

1 reference

12 December 2020

Regulation of anti-HLA antibody-dependent natural killer cell activation by immunosuppressive agents

1 reference

12 December 2020

Complement-fixing donor-specific antibodies identified by a novel C1q assay are associated with allograft loss

1 reference

12 December 2020

Guidelines for the diagnosis of antibody-mediated rejection in pancreas allografts-updated Banff grading schema

1 reference

12 December 2020

Glycan analysis of monoclonal antibodies secreted in deposition disorders indicates that subsets of plasma cells differentially process IgG glycans

1 reference

12 December 2020

The platelet Fc receptor: a new role for an old actor

1 reference

12 December 2020

Outcome of subclinical antibody-mediated rejection in kidney transplant recipients with preformed donor-specific antibodies

1 reference

12 December 2020

Human leukocyte antigen antibodies and human complement activation: role of IgG subclass, specificity, and cytotoxic potential

1 reference

12 December 2020

Pretransplant IgG subclasses of donor-specific human leukocyte antigen antibodies and development of antibody-mediated rejection

1 reference

12 December 2020

Immunoglobulin G subclass analysis of HLA donor specific antibodies in heart and renal transplant recipients

1 reference

12 December 2020

Impact of IgM and IgG3 anti-HLA alloantibodies in primary renal allograft recipients

1 reference

12 December 2020

Detection of complement-fixing and non-fixing antibodies specific for endothelial precursor cells and lymphocytes using flow cytometry

1 reference

12 December 2020

Synergistic deposition of C4d by complement-activating and non-activating antibodies in cardiac transplants

1 reference

12 December 2020

Comparing transplant glomerulopathy in the absence of C4d deposition and donor-specific antibodies to chronic antibody-mediated rejection

1 reference

12 December 2020

C4d-fixing capability of low-level donor-specific HLA antibodies is not predictive for early antibody-mediated rejection

1 reference

12 December 2020

Increased macrophage density of cardiac allograft biopsies is associated with antibody-mediated rejection and alloantibodies to HLA antigens

1 reference

12 December 2020

Circulating donor-specific anti-human leukocyte antigen antibodies and complement C4d deposition are associated with the development of cardiac allograft vasculopathy

1 reference

12 December 2020

Determinants of C1q binding in the single antigen bead assay

1 reference

12 December 2020

Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes

1 reference

12 December 2020

Microdroplet Assay of Human Serum Cytotoxins

1 reference

12 December 2020

10.1016/J.MOLMED.2015.02.004

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801125%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801125%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25801125%20AND%20SRC:MED&resulttype=core&format=json