(Q26863329)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

review article

3 references

11 July 2020

17 July 2021

PU.1 downregulation in murine radiation-induced acute myeloid leukaemia (AML): from molecular mechanism to human AML (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json

radiation-induced leukemia

2 March 2020

main subject

acute myeloid leukemia

7 references

3 April 2019

2 August 2019

11 December 2019

18 December 2019

22 December 2019

23 December 2019

11 July 2020

proto-oncogene proteins

1 reference

2 August 2019

1 reference

11 December 2019

1 reference

18 December 2019

1 reference

22 December 2019

1 reference

23 December 2019

1 reference

radiation-induced neoplasms

11 July 2020

1 reference

11 July 2020

1 reference

1 reference

17 July 2021

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Christophe Badie

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Tom Verbiest

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Simon Bouffler

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

language of work or name

1 reference

6 March 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 April 2015

2 references

11 July 2020

17 July 2021

10 references

3 April 2019

2 August 2019

11 December 2019

18 December 2019

22 December 2019

23 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

11 July 2020

17 July 2021

36

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

413-419

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

issue

4

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 4.0 International

2 March 2020

copyright license

8 references

3 April 2019

2 August 2019

11 December 2019

18 December 2019

22 December 2019

23 December 2019

11 July 2020

on focus list of Wikimedia project

17 July 2021

ScienceSource

0 references

cites work

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

PU.1 (Spi-1) autoregulates its expression in myeloid cells

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

The incidence of leukemia, lymphoma and multiple myeloma among atomic bomb survivors: 1950-2001

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

The origin and evolution of mutations in acute myeloid leukemia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Pre-leukemic evolution of hematopoietic stem cells: the importance of early mutations in leukemogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a- and Arf-independent manner

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Positive feedback between PU.1 and the cell cycle controls myeloid differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Live cell detection of chromosome 2 deletion and Sfpi1/PU1 loss in radiation-induced mouse acute myeloid leukaemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Frequency of acute myeloid leukaemia-associated mouse chromosome 2 deletions in X-ray exposed immature haematopoietic progenitors and stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Molecular characterisation of murine acute myeloid leukaemia induced by 56Fe ion and 137Cs gamma ray irradiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

5-azacitidine in aggressive myelodysplastic syndromes regulates chromatin structure at PU.1 gene and cell differentiation capacity.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

The transcription factor PU.1 is a critical regulator of cellular communication in the immune system

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

A two-mutation model of radiation-induced acute myeloid leukemia using historical mouse data

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Sfpi1/PU.1 mutations in mouse radiation-induced acute myeloid leukaemias affect mRNA and protein abundance and associate with disrupted transcription

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

PU.1 is regulated by NF-kappaB through a novel binding site in a 17 kb upstream enhancer element.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Dose-dependent repression of T-cell and natural killer cell genes by PU.1 enforces myeloid and B-cell identity.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Genetics of therapy-related myelodysplasia and acute myeloid leukemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Is PU.1 a dosage-sensitive regulator of haemopoietic lineage commitment and leukaemogenesis?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Inactivation of PU.1 in adult mice leads to the development of myeloid leukemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Reduced PU.1 expression causes myeloid progenitor expansion and increased leukemia penetrance in mice expressing PML-RARalpha.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Potential autoregulation of transcription factor PU.1 by an upstream regulatory element

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Regulation of macrophage and neutrophil cell fates by the PU.1:C/EBPalpha ratio and granulocyte colony-stimulating factor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Advantages of the CBA mouse in leukemogenesis research

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Molecular mapping of chromosome 2 deletions in murine radiation-induced AML localizes a putative tumor suppressor gene to a 1.0 cM region homologous to human chromosome segment 11p11-12.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Chromosome 2 hypersensitivity and clonal development in murine radiation acute myeloid leukaemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Induction of myeloid leukaemia by whole-body single exposure of CBA male mice to x-rays

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Gene deletion explains both in vivo and in vitro generated chromosome 2 aberrations associated with murine myeloid leukemia.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Implication of replicative stress-related stem cell ageing in radiation-induced murine leukaemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Mutations of the PU.1 Ets domain are specifically associated with murine radiation-induced, but not human therapy-related, acute myeloid leukaemia

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Spi-1 is a putative oncogene in virally induced murine erythroleukaemias.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4392607

Evidence for complex multigenic inheritance of radiation AML susceptibility in mice revealed using a surrogate phenotypic assay.

31 May 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Upregulation of c-myc gene accompanied by PU.1 deficiency in radiation-induced acute myeloid leukemia in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Radiation leukemogenesis in mice: loss of PU.1 on chromosome 2 in CBA and C57BL/6 mice after irradiation with 1 GeV/nucleon 56Fe ions, X rays or gamma rays. Part I. Experimental observations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Allelic loss on chromosome 4 (Lyr2/TLSR5) is associated with myeloid, B-lympho-myeloid, and lymphoid (B and T) mouse radiation-induced leukemias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Flt3-ITD mutations in a mouse model of radiation-induced acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

PU.1 is a suppressor of myeloid leukemia, inactivated in mice by gene deletion and mutation of its DNA binding domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Leukemogenesis in heterozygous PU.1 knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Cell surface marker phenotypes and gene expression profiles of murine radiation-induced acute myeloid leukemia stem cells are similar to those of common myeloid progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Aggressive acute myeloid leukemia in PU.1/p53 double-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

The impact of therapy-related acute myeloid leukemia (AML) on outcome in 2853 adult patients with newly diagnosed AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Heterozygous PU.1 mutations are associated with acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Heterozygous deletion of the PU.1 locus in human AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGV016

Chromosomal instability in acute myelocytic leukemia and myelodysplastic syndrome patients among atomic bomb survivors

21 January 2018

1 reference

12 December 2020

A specific chromosomal deletion in murine leukemic cells induced by radiation with different qualities

1 reference

12 December 2020

Chromosomal abnormalities in neutron-induced acute myeloid leukemias in CBA/H mice

1 reference

12 December 2020

Evidence for clustered tumour suppressor gene loci on mouse chromosomes 2 and 4 in radiation-induced acute myeloid leukaemia

1 reference

12 December 2020

Lentiviral PU.1 overexpression restores differentiation in myeloid leukemic blasts

1 reference

12 December 2020

The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

1 reference

12 December 2020

Identifiers

DOI

10.1093/CARCIN/BGV016

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json

release_bmw7w4h63bhbxftcxgpouw7xce

2 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bmw7w4h63bhbxftcxgpouw7xce

24 November 2022

mapped directly with Wikidata item

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25750172%20AND%20SRC:MED&resulttype=core&format=json