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AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function
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review article
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Europe PubMed Central
title
AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function
(English)
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stated in
PubMed
main subject
cell function
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author name string
D. G. Hardie
series ordinal
1
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Crossref
language of work or name
English
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stated in
PubMed
publication date
15 September 2011
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stated in
PubMed
published in
Genes & Development
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stated in
PubMed
volume
25
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PubMed
issue
18
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PubMed
page(s)
1895-908
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PubMed
cites work
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21 March 2017
AMPK and PPARdelta agonists are exercise mimetics
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21 March 2017
AMPK phosphorylation of raptor mediates a metabolic checkpoint
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21 March 2017
AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5
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21 March 2017
Structural basis for AMP binding to mammalian AMP-activated protein kinase
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21 March 2017
Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta
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PubMed Central
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21 March 2017
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
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21 March 2017
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
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21 March 2017
CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations
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21 March 2017
Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
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21 March 2017
AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
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21 March 2017
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
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21 March 2017
Role of AMP-activated protein kinase in mechanism of metformin action
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21 March 2017
Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
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21 March 2017
The regulation of AMP-activated protein kinase by phosphorylation
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28 September 2017
Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1
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21 March 2017
Mechanism of inhibition of bovine F1-ATPase by resveratrol and related polyphenols
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21 March 2017
Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase
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21 March 2017
Resveratrol improves health and survival of mice on a high-calorie diet
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21 March 2017
TSC2 mediates cellular energy response to control cell growth and survival
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21 March 2017
Snf1 protein kinase and the repressors Nrg1 and Nrg2 regulate FLO11, haploid invasive growth, and diploid pseudohyphal differentiation
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21 March 2017
Antagonistic controls of autophagy and glycogen accumulation by Snf1p, the yeast homolog of AMP-activated protein kinase, and the cyclin-dependent kinase Pho85p
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21 March 2017
Glucose depletion causes haploid invasive growth in yeast
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21 March 2017
beta-subunits of Snf1 kinase are required for kinase function and substrate definition
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21 March 2017
Isolation and characterization of yeast mutants defective in intermediary carbon metabolism and in carbon catabolite derepression
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21 March 2017
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome
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21 March 2017
Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis
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PubMed Central
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21 March 2017
Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung
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21 March 2017
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
1 reference
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PubMed Central
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21 March 2017
A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle
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PubMed Central
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21 March 2017
Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398
1 reference
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PubMed Central
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21 March 2017
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase
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21 March 2017
Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase
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PubMed Central
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21 March 2017
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
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PubMed Central
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21 March 2017
AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice
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PubMed Central
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21 March 2017
Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle
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21 March 2017
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
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21 March 2017
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
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PubMed Central
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21 March 2017
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade
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PubMed Central
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21 March 2017
Activation of GLUT1 by metabolic and osmotic stress: potential involvement of AMP-activated protein kinase (AMPK)
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21 March 2017
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
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7 April 2017
The energetics of genome complexity
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7 April 2017
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
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7 April 2017
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
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7 April 2017
Metabolic control through the PGC-1 family of transcription coactivators
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7 April 2017
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism
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7 April 2017
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
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7 April 2017
Metformin and reduced risk of cancer in diabetic patients
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7 April 2017
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
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7 April 2017
5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?
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7 April 2017
The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis
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7 April 2017
LKB1 modulates lung cancer differentiation and metastasis
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25 May 2017
AMP-activated protein kinase: also regulated by ADP?
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28 September 2017
β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK).
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28 September 2017
Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
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28 September 2017
Hispidulin potently inhibits human glioblastoma multiforme cells through activation of AMP-activated protein kinase (AMPK).
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28 September 2017
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
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28 September 2017
Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase
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28 September 2017
Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation
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28 September 2017
Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle
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28 September 2017
Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase
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28 September 2017
Autophagy in cellular growth control
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28 September 2017
Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP.
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28 September 2017
AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply
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28 September 2017
Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells
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28 September 2017
Association of AMP-activated protein kinase subunits with glycogen particles as revealed in situ by immunoelectron microscopy
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PubMed Central
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28 September 2017
Somatic LKB1 mutations promote cervical cancer progression
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28 September 2017
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans
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PubMed Central
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28 September 2017
TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells.
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28 September 2017
Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation
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28 September 2017
C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest
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28 September 2017
Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
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28 September 2017
Mechanisms underlying the metabolic actions of galegine that contribute to weight loss in mice
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28 September 2017
SNF1/AMPK pathways in yeast
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Oligosaccharide recognition and binding to the carbohydrate binding module of AMP-activated protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
The complement of protein kinases of the microsporidium Encephalitozoon cuniculi in relation to those of Saccharomyces cerevisiae and Schizosaccharomyces pombe
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Energy-dependent regulation of cell structure by AMP-activated protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
LKB1 and AMPK maintain epithelial cell polarity under energetic stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
SNF1/AMPK/SnRK1 kinases, global regulators at the heart of energy control?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
AMP-activated protein kinase regulates the assembly of epithelial tight junctions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Expanding role of AMPK in endocrinology.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Structural basis for glycogen recognition by AMP-activated protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Snf1-related protein kinase 1 is needed for growth in a normal day-night light cycle.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
AMPK beta subunit targets metabolic stress sensing to glycogen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
A homologue of AMP-activated protein kinase in Drosophila melanogaster is sensitive to AMP and is activated by ATP depletion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
AMP-activated protein kinase: the energy charge hypothesis revisited
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Method for the quantitative extraction of resveratrol and piceid isomers in grape berry skins. Effect of powdery mildew on the stilbene content.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
The structure of the catalytic portion of human HMG-CoA reductase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Chronic activation of 5'-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Snf1 kinase connects nutritional pathways controlling meiosis in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
N-terminal mutations modulate yeast SNF1 protein kinase function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
Genetics of carbon catabolite repression in Saccharomyces cerevisiae: genes involved in the derepression process
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 September 2017
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
31 May 2018
A null mutation in skeletal muscle FAT/CD36 reveals its essential role in insulin- and AICAR-stimulated fatty acid metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
31 May 2018
Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
31 May 2018
Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
31 May 2018
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
31 May 2018
5'-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
31 May 2018
A hierarchy of ATP-consuming processes in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
31 May 2018
Mutants of yeast defective in sucrose utilization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
31 May 2018
AMPK is a direct adenylate charge-regulated protein kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 November 2018
Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 November 2018
Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 November 2018
Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 November 2018
A central integrator of transcription networks in plant stress and energy signalling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 November 2018
Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 November 2018
Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 November 2018
Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 November 2018
The alpha2-5'AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 November 2018
AICA riboside both activates AMP-activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 November 2018
Protein kinase substrate recognition studied using the recombinant catalytic domain of AMP-activated protein kinase and a model substrate.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 November 2018
AMP-activated protein kinase inhibits the glucose-activated expression of fatty acid synthase gene in rat hepatocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 November 2018
Specificity determinants for the AMP-activated protein kinase and its plant homologue analysed using synthetic peptides.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3185962
retrieved
28 November 2018
The evolution of putative starch-binding domains
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21937710
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The substrate and sequence specificity of the AMP-activated protein kinase. Phosphorylation of glycogen synthase and phosphorylase kinase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21937710
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Diurnal rhythm of phosphorylation of rat liver acetyl-CoA carboxylase by the AMP-activated protein kinase, demonstrated using freeze-clamping. Effects of high fat diets
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21937710
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Evidence for a protein kinase cascade in higher plants. 3-Hydroxy-3-methylglutaryl-CoA reductase kinase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21937710
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Similar substrate recognition motifs for mammalian AMP-activated protein kinase, higher plant HMG-CoA reductase kinase-A, yeast SNF1, and mammalian calmodulin-dependent protein kinase I
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21937710
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
5'-AMP activates the AMP-activated protein kinase cascade, and Ca2+/calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21937710
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Glucose repression/derepression in budding yeast: SNF1 protein kinase is activated by phosphorylation under derepressing conditions, and this correlates with a high AMP:ATP ratio
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21937710
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The 5'-AMP-activated protein kinase inhibits the transcriptional stimulation by glucose in liver cells, acting through the glucose response complex
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21937710
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
AMP-activated protein kinase phosphorylation of endothelial NO synthase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21937710
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Regulation of spinach SNF1-related (SnRK1) kinases by protein kinases and phosphatases is associated with phosphorylation of the T loop and is regulated by 5'-AMP
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21937710
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1101/GAD.17420111
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
204151
OpenCitations bibliographic resource ID
204151
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
204151
PMC publication ID
3185962
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
204151
PubMed publication ID
21937710
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
204151
ResearchGate publication ID
51661452
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