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Structure and mechanism of non-histone protein acetyltransferase enzymes
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title
Structure and mechanism of non-histone protein acetyltransferase enzymes
(English)
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PubMed
author
Ronen Marmorstein
series ordinal
2
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author name string
David R. Friedmann
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1
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Crossref
language of work or name
English
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stated in
PubMed
publication date
November 2013
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stated in
PubMed
published in
FEBS Journal
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stated in
PubMed
volume
280
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PubMed
issue
22
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stated in
PubMed
page(s)
5570-81
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PubMed
cites work
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MYST protein acetyltransferase activity requires active site lysine autoacetylation
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Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival
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Autoacetylation of the histone acetyltransferase Rtt109
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MEC-17 is an alpha-tubulin acetyltransferase
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Acetylation is indispensable for p53 activation
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Yeast Rtt109 promotes genome stability by acetylating histone H3 on lysine 56
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ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS
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Atomic resolution structure of human -tubulin acetyltransferase bound to acetyl-CoA
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Cyclic AMP regulation of protein lysine acetylation in Mycobacterium tuberculosis
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N-Terminal Acetylation Acts as an Avidity Enhancer Within an Interconnected Multiprotein Complex
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21 March 2017
Structure of a Ternary Naa50p (NAT5/SAN) N-terminal Acetyltransferase Complex Reveals the Molecular Basis for Substrate-specific Acetylation
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Structure and Biochemical Characterization of Protein Acetyltransferase from Sulfolobus solfataricus
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Molecular basis for the autoregulation of the protein acetyl transferase Rtt109
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Structural insights into histone H3 lysine 56 acetylation by Rtt109
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Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP
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Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
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Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide
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Crystal structure of the histone acetyltransferase domain of the human PCAF transcriptional regulator bound to coenzyme A
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Lysine acetylation targets protein complexes and co-regulates major cellular functions
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Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
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The transcriptional coactivators p300 and CBP are histone acetyltransferases
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The major alpha-tubulin K40 acetyltransferase alphaTAT1 promotes rapid ciliogenesis and efficient mechanosensation
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Hos1 deacetylates Smc3 to close the cohesin acetylation cycle.
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Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion
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Acetylation of Smc3 by Eco1 is required for S phase sister chromatid cohesion in both human and yeast
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Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication
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Microtubule acetylation promotes kinesin-1 binding and transport.
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HAT1 and HAT2 proteins are components of a yeast nuclear histone acetyltransferase enzyme specific for free histone H4.
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Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation
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Identification of a gene encoding a yeast histone H4 acetyltransferase
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Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.
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The CBP co-activator is a histone acetyltransferase
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Duration of nuclear NF-kappaB action regulated by reversible acetylation
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21 March 2017
Deacetylation of p53 modulates its effect on cell growth and apoptosis
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Protein N-terminal acetyltransferases: when the start matters
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21 March 2017
Acetylation of non-histone proteins modulates cellular signalling at multiple levels
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21 March 2017
HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention
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21 March 2017
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey
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21 March 2017
The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60
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21 March 2017
Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interactive protein Tip60
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21 March 2017
Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300
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21 March 2017
Reversible acetylation and inactivation of Mycobacterium tuberculosis acetyl-CoA synthetase is dependent on cAMP
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21 March 2017
Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux
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7 April 2017
Acetylation and deacetylation of non-histone proteins
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7 April 2017
Protein kinases--the major drug targets of the twenty-first century?
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7 April 2017
Acetylation: a regulatory modification to rival phosphorylation?
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7 April 2017
Tubulin acetyltransferase αTAT1 destabilizes microtubules independently of its acetylation activity
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28 September 2017
Histone acetyltransferases: Rising ancient counterparts to protein kinases
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28 September 2017
Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways
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28 September 2017
The protein acetylome and the regulation of metabolism
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28 September 2017
N-terminal acetylation inhibits protein targeting to the endoplasmic reticulum
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28 September 2017
Histone onco-modifications
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28 September 2017
Modulations of hMOF autoacetylation by SIRT1 regulate hMOF recruitment and activities on the chromatin
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28 September 2017
Comprehensive lysine acetylomes emerging from bacteria to humans
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28 September 2017
N-terminal acetylation of cellular proteins creates specific degradation signals
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28 September 2017
Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humans
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28 September 2017
Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli
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28 September 2017
A decade of histone acetylation: marking eukaryotic chromosomes with specific codes
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28 September 2017
AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR.
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28 September 2017
Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine
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28 September 2017
The origins of protein phosphorylation
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28 September 2017
Histone acetylation: a switch between repressive and permissive chromatin. Second in review series on chromatin dynamics.
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28 September 2017
Histone acetylation and disease
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28 September 2017
Regulation of gene expression by transcription factor acetylation
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28 September 2017
Acetylation of importin-alpha nuclear import factors by CBP/p300.
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28 September 2017
Regulation of E2F1 activity by acetylation
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28 September 2017
Acetylation of MyoD directed by PCAF is necessary for the execution of the muscle program
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28 September 2017
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.
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PubMed Central
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28 September 2017
ESA1 is a histone acetyltransferase that is essential for growth in yeast
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013100
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28 September 2017
Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors.
1 reference
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28 September 2017
Microtubules containing acetylated alpha-tubulin in mammalian cells in culture
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28 September 2017
Calorie restriction alters mitochondrial protein acetylation
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Multiple roles for acetylation in the interaction of p300 HAT with ATF-2.
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31 May 2018
Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis
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PubMed Central
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31 May 2018
Regulation of the p300 HAT domain via a novel activation loop.
1 reference
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31 May 2018
Acetylation of the p53 DNA-binding domain regulates apoptosis induction
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21 January 2018
Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosome
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21 January 2018
Coordination of a transcriptional switch by HMGI(Y) acetylation
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21 January 2018
A molecular determinant for the establishment of sister chromatid cohesion
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21 January 2018
E2F Family Members Are Differentially Regulated by Reversible Acetylation
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PubMed
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Acetylation of MyoD by p300 requires more than its histone acetyltransferase domain
1 reference
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PubMed
reference URL
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Evidence that approximately eighty per cent of the soluble proteins from Ehrlich ascites cells are Nalpha-acetylated
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23742047
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Chlamydomonas alpha-tubulin is posttranslationally modified by acetylation on the epsilon-amino group of a lysine
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23742047
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1111/FEBS.12373
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4731815
OpenCitations bibliographic resource ID
4731815
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4731815
PMC publication ID
4013100
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4731815
PubMed publication ID
23742047
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4731815
ResearchGate publication ID
237068392
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