(Q27000813)

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3 March 2020

2 references

22 October 2022

26 October 2022

NS3 protease from hepatitis C virus: biophysical studies on an intrinsically disordered protein domain (English)

1 reference

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3 March 2020

0 references

1 reference

3 November 2019

1 reference

23 December 2019

1 reference

Carlos Marcuello Anglés

3

1 reference

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3 March 2020

Anabel Lostao

4

1 reference

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3 March 2020

Olga Abian

5

1 reference

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3 March 2020

Adrian Velazquez-campoy

6

1 reference

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3 March 2020

author name string

Sonia Vega

1

2 references

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3 March 2020

Jose L Neira

2

1 reference

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3 March 2020

language of work or name

1 reference

26 June 2013

6 references

3 November 2019

23 December 2019

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3 March 2020

22 October 2022

26 October 2022

International Journal of Molecular Sciences

6 references

3 November 2019

23 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23803659%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

22 October 2022

26 October 2022

14

2 references

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3 March 2020

issue

7

2 references

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3 March 2020

page(s)

13282-13306

1 reference

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Creative Commons Attribution 3.0 Unported

3 March 2020

copyright license

4 references

3 November 2019

23 December 2019

22 October 2022

26 October 2022

0 references

Atomic force microscope

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Relative Replication Capacity and Selective Advantage Profiles of Protease Inhibitor-Resistant Hepatitis C Virus (HCV) NS3 Protease Mutants in the HCV Genotype 1b Replicon System

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Complex of NS3 protease and NS4A peptide of BK strain hepatitis C virus: A 2.2 Å resolution structure in a hexagonal crystal form

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

In vitro study of the NS2-3 protease of hepatitis C virus

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

The NS3 proteinase domain of hepatitis C virus is a zinc-containing enzyme

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Entropy-enthalpy transduction caused by conformational shifts can obscure the forces driving protein-ligand binding

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Mechanical processes in biochemistry

21 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

21 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Calculation of hydrodynamic properties of globular proteins from their atomic-level structure

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

A second hepatitis C virus-encoded proteinase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Imaging the spatial orientation of subunits within membrane receptors by atomic force microscopy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Conformational stability of hepatitis C virus NS3 protease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Cytosolic zinc buffering and muffling: their role in intracellular zinc homeostasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Understanding protein non-folding.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Intrinsically disordered proteins and their environment: effects of strong denaturants, temperature, pH, counter ions, membranes, binding partners, osmolytes, and macromolecular crowding

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Atomic force microscopy of the bacterial photosynthetic apparatus: plain pictures of an elaborate machinery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Atomic force microscopy as a multifunctional molecular toolbox in nanobiotechnology.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Atomic force microscopy reveals the stoichiometry and subunit arrangement of the alpha4beta3delta GABA(A) receptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Stabilizing effect of Zn2+ in native bovine rhodopsin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Resistance of hepatitis C virus to NS3-4A protease inhibitors: mechanisms of drug resistance induced by R155Q, A156T, D168A and D168V mutations.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Hepatitis C virus NS2/3 processing is required for NS3 stability and viral RNA replication

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Detection and characterization of partially unfolded oligomers of the SH3 domain of alpha-spectrin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Protein Structure and the Energetics of Protein Stability.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

The metal binding site of the hepatitis C virus NS3 protease. A spectroscopic investigation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

AFM study of morphology and mechanical properties of a chimeric spider silk and bone sialoprotein protein for bone regeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Structural and Functional Aspects of Metal Sites in Biology

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Hydrodynamic radii of native and denatured proteins measured by pulse field gradient NMR techniques.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Complex formation between the hepatitis C virus serine protease and a synthetic NS4A cofactor peptide

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

A zinc binding site in viral serine proteinases

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Spectroscopic characterization of rhinoviral protease 2A: Zn is essential for the structural integrity

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742187

Discovery and development of telaprevir: an NS3-4A protease inhibitor for treating genotype 1 chronic hepatitis C virus

31 May 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Analysis of long-term persistence of resistance mutations within the hepatitis C virus NS3 protease after treatment with telaprevir or boceprevir

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Thermodynamics of zinc binding to hepatitis C virus NS3 protease: a folding by binding event

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Use of the fused NS4A peptide-NS3 protease domain to study the importance of the helicase domain for protease inhibitor binding to hepatitis C virus NS3-NS4A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Physical basis of structural and catalytic Zn-binding sites in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Characterisation of the role of zinc in the hepatitis C virus NS2/3 auto-cleavage and NS3 protease activities

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Mechanism of autoproteolysis at the NS2-NS3 junction of the hepatitis C virus polyprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

A central hydrophobic domain of the hepatitis C virus NS4A protein is necessary and sufficient for the activation of the NS3 protease

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Cd(II), Pb(II) and Zn(II) ions regulate expression of the metal-transporting P-type ATPase ZntA in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

ZntR is a Zn(II)-responsive MerR-like transcriptional regulator of zntA in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Extreme zinc-binding thermodynamics of the metal sensor/regulator protein, ZntR.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Coupling ligand recognition to protein folding in an engineered variant of rabbit ileal lipid binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Size-dependent properties of magnetoferritin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Oligomerization properties of FurA from the cyanobacterium Anabaena sp. PCC 7120: direct visualization by in situ atomic force microscopy under different redox conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Detection of a quaternary organization into dimer of trimers of Corynebacterium ammoniagenes FAD synthetase at the single-molecule level and at the in cell level

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

WSXM: a software for scanning probe microscopy and a tool for nanotechnology.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

A continuous assay of hepatitis C virus protease based on resonance energy transfer depsipeptide substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Calibration of atomic‐force microscope tips

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Characterisation of protein unfolding by NMR diffusion measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713282

Mannan-Binding Lectin: Structure, Oligomerization, and Flexibility Studied by Atomic Force Microscopy

21 January 2018

1 reference

12 December 2020

Effects of zinc binding on the structure and dynamics of the intrinsically disordered protein prothymosin alpha: evidence for metalation as an entropic switch

1 reference

12 December 2020

Quantification of tip-broadening in non-contact atomic force microscopy with carbon nanotube tips

1 reference

12 December 2020

Measurement of diffusion constants for nucleic acids by NMR

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS140713282

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23803659%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23803659%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23803659%20AND%20SRC:MED&resulttype=core&format=json