(Q27006513)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Facts and fiction: the impact of hypothermia on molecular mechanisms following major challenge (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Martijn van Griensven

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Michael Frink

1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Philipp Mommsen

4

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Frank Hildebrand

5

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

language of work or name

1 reference

13 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json

Mediators of Inflammation

28 January 2020

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

volume

2012

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

762840

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

28 January 2020

copyright license

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Cortical cell death induced by IL-1 is mediated via actions in the hypothalamus of the rat

28 September 2017

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28 September 2017

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BCL-2 family: regulators of cell death

28 September 2017

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Intraischemic hypothermia attenuates neutrophil infiltration in the rat neocortex after focal ischemia-reperfusion injury

28 September 2017

1 reference

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Cytokines in inflammatory brain lesions: helpful and harmful

28 September 2017

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Brain damage and temperature: cellular and molecular mechanisms.

28 September 2017

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Leukocyte-endothelial adhesion molecules

28 September 2017

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New horizons in management of hypothermia and frostbite injury

28 September 2017

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Mechanisms and consequences of leukocyte-endothelial interaction

28 September 2017

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Reactive oxygen species and the central nervous system

28 September 2017

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Neurochemical mechanisms in brain injury and treatment: a review

28 September 2017

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An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat.

28 September 2017

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Post-ischemic hypothermia promotes generation of neural cells and reduces apoptosis by Bcl-2 in the striatum of neonatal rat brain.

28 September 2017

1 reference

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Abrogation of NF-κB signaling in human neutrophils induces neutrophil survival through sustained p38-MAPK activation.

31 May 2018

1 reference

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Effects of citicoline used alone and in combination with mild hypothermia on apoptosis induced by focal cerebral ischemia in rats

31 May 2018

1 reference

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Hypothermia induces T-cell production of immunosuppressive cytokines

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

Topical hepatic hypothermia attenuates pulmonary injury after hepatic ischemia and reperfusion.

31 May 2018

1 reference

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Interleukin-1beta and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

Cortical protection by localized striatal injection of IL-1ra following cerebral ischemia in the rat.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

Interleukin-1 in cerebral ischemia.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

Moderate hypothermia reduces postischemic edema development and leukotriene production

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

L-selectin function is required for beta 2-integrin-mediated neutrophil adhesion at physiological shear rates in vivo.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

Hypothermia attenuates ischemia/reperfusion-induced endothelial cell apoptosis via alterations in apoptotic pathways and JNK signaling

31 May 2018

1 reference

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Profound hypothermia decreases cardiac apoptosis through Akt survival pathway.

21 January 2018

1 reference

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Changes in interleukin-10 mRNA expression are predictive for 9-day survival of pigs in an emergency preservation and resuscitation model.

21 January 2018

1 reference

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Hypothermia protects against endotoxin-induced acute lung injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Early induction of moderate hypothermia suppresses systemic inflammatory cytokines and intracellular adhesion molecule-1 in rats with caerulein-induced pancreatitis and endotoxemia

21 January 2018

1 reference

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Induced hypothermia attenuates the acute lung injury in hemorrhagic shock

21 January 2018

1 reference

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Moderate hypothermia blunts the inflammatory response and reduces organ injury after acute haemorrhage

21 January 2018

1 reference

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Inflammatory effects of hypothermia and inhaled H2S during resuscitated, hyperdynamic murine septic shock

21 January 2018

1 reference

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Tumor necrosis factor alpha expression and protein levels after fluid percussion injury in rats: the effect of injury severity and brain temperature.

21 January 2018

1 reference

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The effects of body temperature control on cytokine production in a rat model of ventilator-induced lung injury

21 January 2018

1 reference

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The relationship of ischemia-reperfusion injury of transplanted lung and the up-regulation of major histocompatibility complex II on host peripheral lymphocytes

21 January 2018

1 reference

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Effect of moderate hypothermia on systemic and internal jugular plasma IL-6 levels after traumatic brain injury in humans

21 January 2018

1 reference

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Hypothermia downregulates inflammation but enhances IL-6 secretion by stimulated endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Hypothermia after cardiac arrest does not alter serum inflammatory markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Perfusion temperature, thyroid hormones and inflammation during pediatric cardiac surgery

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Mild hypothermia inhibits inflammation after experimental stroke and brain inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Hypothermic versus normothermic cardiopulmonary bypass: influence on circulating adhesion molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Does hypothermic treatment provide an advantage after spinal cord injury until surgery? An experimental study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Brain cooling causes attenuation of cerebral oxidative stress, systemic inflammation, activated coagulation, and tissue ischemia/injury during heatstroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Combination effect of systemic hypothermia and caspase inhibitor administration against hypoxic-ischemic brain damage in neonatal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Hypothermic protection of the ischemic heart via alterations in apoptotic pathways as assessed by gene array analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Mcl-1-mediated impairment of the intrinsic apoptosis pathway in circulating neutrophils from critically ill patients can be overcome by Fas stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Hypothermia inhibits Fas-mediated apoptosis of primary mouse hepatocytes in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Therapeutic hypothermia modulates TNFR1 signaling in the traumatized brain via early transient activation of the JNK pathway and suppression of XIAP cleavage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Mild hypothermia reduces ischemic neuron death via altering the expression of p53 and bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Keratinocyte-derived chemokine plays a critical role in the induction of systemic inflammation and tissue damage after trauma-hemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Increased matrix metalloproteinase-9 in blood in association with activation of interleukin-6 after traumatic brain injury: influence of hypothermic therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Induction of interleukin-1 beta mRNA after focal cerebral ischaemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Mechanisms of hypothermia-induced cell protection mediated by microglial cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Effects of mild hypothermia on survival and serum cytokines in uncontrolled hemorrhagic shock in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Rapid rewarming after mild hypothermia accentuates the inflammatory response after acute volume controlled haemorrhage in spontaneously breathing rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Intrahepatic synthesis of tumor necrosis factor-alpha related to cardiac surgery is inhibited by interleukin-10 via the Janus kinase (Jak)/signal transducers and activator of transcription (STAT) pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Induced mild hypothermia reduces mortality during acute inflammation in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Effects of induced hypothermia after soft-tissue injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Mild hypothermia during hemorrhagic shock in rats improves survival without significant effects on inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Moderate hypothermia suppresses jugular venous superoxide anion radical, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

The effects of systemic hypothermia on a murine model of thoracic aortic ischemia reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

The long-term effects of mild to moderate hypothermia on gray and white matter injury after spinal cord ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

The role of nitric oxide synthase and heme oxygenase in the protective effect of hypothermia in ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

The role of hypothermia in the management of severe brain injury: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Effect of speed of rewarming and administration of anti-inflammatory or anti-oxidant agents on acute lung injury in an intestinal ischemia model treated with therapeutic hypothermia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Effects of hypothermia and re-warming on the inflammatory response in a murine multiple hit model of trauma

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F762840

Guidelines for the management of severe traumatic brain injury. III. Prophylactic hypothermia

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

The use of controlled mild hypothermia and immune system status in patients with severe brain injury.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

Effect of intraischemic mild hypothermia on interleukin-1beta and monocyte chemoattractant protein-1 contents in ischemic core of rat cortex after transient focal cerebral ischemia

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

Therapeutic hypothermia for head injury.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

Effects of moderate hypothermia on IL-1 beta-induced leukocyte rolling and adhesion in pial microcirculation of mice and on proinflammatory gene expression in human cerebral endothelial cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

Initiating mechanisms involved in the pathobiology of traumatically induced axonal injury and interventions targeted at blunting their progression

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

Excitotoxic brain damage in the rat induces interleukin-1beta protein in microglia and astrocytes: correlation with the progression of cell death

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

The progression and topographic distribution of interleukin-1beta expression after permanent middle cerebral artery occlusion in the rat.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

Implications of admission hypothermia in trauma patients.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3316953

[The influence of hypothermia therapy on enzymology and pathology of lung after cardiac arrest]

28 November 2018

1 reference

12 December 2020

Influence of Temperature on Neutrophil Trafficking During Clinical Cardiopulmonary Bypass

1 reference

12 December 2020

Early polymorphonuclear leukocyte accumulation correlates with the development of posttraumatic cerebral edema in rats

1 reference

12 December 2020

Hypothermic preservation of lung allograft inhibits cytokine-induced chemoattractant-1, endothelial leucocyte adhesion molecule, vascular cell adhesion molecule-1 and intracellular adhesion molecule-1 expression

1 reference

12 December 2020

Early Hypothermia in Severely Injured Trauma Patients Is a Significant Risk Factor for Multiple Organ Dysfunction Syndrome but Not Mortality

1 reference

12 December 2020

Topic liver hypothermia and ischemic preconditioning: a new model of ischemia and reperfusion in rats

1 reference

12 December 2020

Hypothermia inhibits human E-selectin transcription

1 reference

12 December 2020

Evaluation of early macrophage activation and NF-kappaB activity in pulmonary injury caused by deep hypothermia circulatory arrest: an experimental study

1 reference

12 December 2020

Mild hypothermia reduces ICAM-1 expression, neutrophil infiltration and microglia/monocyte accumulation following experimental stroke

1 reference

12 December 2020

Influence of temperature during cardiopulmonary bypass on leukocyte activation, cytokine balance, and post-operative organ damage

1 reference

12 December 2020

Early inflammatory response to carrageenan in the pleural cavity and paw of rats with altered body temperature

1 reference

12 December 2020

[Management of accidental hypothermia]

1 reference

12 December 2020

Importance of posttraumatic hypothermia and hyperthermia on the inflammatory response after fluid percussion brain injury: biochemical and immunocytochemical studies

1 reference

12 December 2020

Incidence and timing of hypothermia in trauma patients undergoing operations

1 reference

12 December 2020

Posttraumatic hypothermia reduces polymorphonuclear leukocyte accumulation following spinal cord injury in rats

1 reference

12 December 2020

Detection of Free Radical Activity During Transient Global Ischemia and Recirculation: Effects of Intraischemic Brain Temperature Modulation

1 reference

12 December 2020

In situ hybridization study of interleukin-1β mRNA induced by kainic acid in the rat brain

1 reference

12 December 2020

The role of inflammatory processes in the pathophysiology and treatment of brain and spinal cord trauma

1 reference

12 December 2020

Responses to trauma: fifty years of ebb and flow

1 reference

12 December 2020

Closed head injury--an inflammatory disease?

1 reference

12 December 2020

Incidence and effect of hypothermia in seriously injured patients

1 reference

12 December 2020

Hypothemia Reversibly Inhibits Endothelial Cell Expression of E-Selectin and Tissue Factor

1 reference

12 December 2020

Different pattern of local and systemic release of proinflammatory and anti-inflammatory mediators in severely injured patients with chest trauma

1 reference

12 December 2020

Induction of profound hypothermia modulates the immune/inflammatory response in a swine model of lethal hemorrhage

1 reference

12 December 2020

Comparison of three methods of rewarming from hypothermia: advantages of extracorporeal blood warming

1 reference

12 December 2020

Role of hypothermia induced by tumor necrosis factor on apoptosis and function of inflammatory neutrophils in mice

1 reference

12 December 2020

Cerebral ischemia and trauma-different etiologies yet similar mechanisms: neuroprotective opportunities

1 reference

12 December 2020

Hypothermia in trauma victims: an ominous predictor of survival

1 reference

12 December 2020

Moderate hypothermia delays proinflammatory cytokine production of human peripheral blood mononuclear cells

1 reference

12 December 2020

Effects of hypothermia and hyperthermia on cytokine production by cultured human mononuclear phagocytes from adults and newborns

1 reference

12 December 2020

Partial recovery of neutrophil functions during prolonged hypothermia in pigs

1 reference

12 December 2020

Is hypothermia in the victim of major trauma protective or harmful? A randomized, prospective study

1 reference

12 December 2020

Identifiers

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22481864%20AND%20SRC:MED&resulttype=core&format=json