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Temperature sensitivity of two-pore (K2P) potassium channels
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4794111
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25366235%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
review article
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title
Temperature sensitivity of two-pore (K2P) potassium channels
(English)
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Europe PubMed Central
PMCID
4794111
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25366235%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
author
Eve R Schneider
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1
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Europe PubMed Central
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4794111
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25366235%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
Elena Gracheva
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3
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Europe PubMed Central
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4794111
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25366235%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
Sviatoslav N Bagriantsev
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4
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4794111
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25366235%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
author name string
Evan O Anderson
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2
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4794111
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25366235%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
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English
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publication date
1 January 2014
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4794111
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22 February 2020
published in
Current Topics in Membranes
2 references
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PubMed
stated in
Europe PubMed Central
PMCID
4794111
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25366235%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
volume
74
2 references
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PubMed
stated in
Europe PubMed Central
PMCID
4794111
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25366235%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
page(s)
113-133
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Europe PubMed Central
PMCID
4794111
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25366235%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
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Regulation of Monocyte Chemotactic Protein-1 secretion by the Two-Pore-Domain Potassium (K2P) channel TREK-1 in human alveolar epithelial cells
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A sensory-labeled line for cold: TRPM8-expressing sensory neurons define the cellular basis for cold, cold pain, and cooling-mediated analgesia
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Variants of stretch-activated two-pore potassium channel TREK-1 associated with preterm labor in humans
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Metabolic and thermal stimuli control K(2P)2.1 (TREK-1) through modular sensory and gating domains
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A Role for K2P Channels in the Operation of Somatosensory Nociceptors
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External Ba2+ block of the two-pore domain potassium channel TREK-1 defines conformational transition in its selectivity filter
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TRP vanilloid 2 knock-out mice are susceptible to perinatal lethality but display normal thermal and mechanical nociception.
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28 September 2017
Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.
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28 September 2017
Low susceptibility to inert gases and pressure symptoms in TREK-1-deficient mice
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28 September 2017
Disruption of the IS6-AID linker affects voltage-gated calcium channel inactivation and facilitation
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28 September 2017
Alternative translation initiation in rat brain yields K2P2.1 potassium channels permeable to sodium
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28 September 2017
Gating at the selectivity filter in cyclic nucleotide-gated channels
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28 September 2017
Altered acetylcholine, bradykinin and cutaneous pressure-induced vasodilation in mice lacking the TREK1 potassium channel: the endothelial link
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
Molecular determinants of gating at the potassium-channel selectivity filter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
Two-pore-domain potassium channels support anion secretion from human airway Calu-3 epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
The stretch-activated potassium channel TREK-1 in rat cardiac ventricular muscle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
A phospholipid sensor controls mechanogating of the K+ channel TREK-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
TREK-1, a K+ channel involved in neuroprotection and general anesthesia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
The pore helix is involved in stabilizing the open state of inwardly rectifying K+ channels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
An intracellular proton sensor commands lipid- and mechano-gating of the K(+) channel TREK-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
Cns distribution of members of the two-pore-domain (KCNK) potassium channel family.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and periphery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
TREK-1 is a heat-activated background K(+) channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
TRAAK is a mammalian neuronal mechano-gated K+ channel.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 September 2017
Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
31 May 2018
TREK-1, a K+ channel involved in polymodal pain perception
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
31 May 2018
Point: Heat-induced membrane depolarization of hypothalamic neurons: a putative mechanism of central thermosensitivity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
31 May 2018
The Thermosensitive Potassium Channel TREK-1 Contributes to Coolness-Evoked Responses of Grueneberg Ganglion Neurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
An increased TREK-1-like potassium current in ventricular myocytes during rat cardiac hypertrophy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
Involvement of TREK-1 activity in astrocyte function and neuroprotection under simulated ischemia conditions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
Neuroprotective role of the TREK-1 channel in decompression sickness.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
Regional differential expression of TREK-1 at left ventricle in myocardial infarction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
Immunohistochemical colocalization of TREK-1, TREK-2 and TRAAK with TRP channels in the trigeminal ganglion cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
Stretch-activated potassium channels in hypotonically induced blebs of atrial myocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
A novel mechanism for human K2P2.1 channel gating. Facilitation of C-type gating by protonation of extracellular histidine residues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
TRESK two-pore-domain K+ channels constitute a significant component of background potassium currents in murine dorsal root ganglion neurones.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
Ionic channels and conductance-based models for hypothalamic neuronal thermosensitivity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
Evidence for two-pore domain potassium channels in rat cerebral arteries.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
TREK-2 (K2P10.1) and TRESK (K2P18.1) are major background K+ channels in dorsal root ganglion neurons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
Temperature effects on neuronal membrane potentials and inward currents in rat hypothalamic tissue slices.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
KCNKØ: opening and closing the 2-P-domain potassium leak channel entails "C-type" gating of the outer pore.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794111
retrieved
28 November 2018
Inverse coupling in leak and voltage-activated K+ channel gates underlies distinct roles in electrical signaling
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25366235
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A disulphide-linked heterodimer of TWIK-1 and TREK-1 mediates passive conductance in astrocytes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25366235
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25366235
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/B978-0-12-800181-3.00005-1
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
4794111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25366235%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
PMCID
4794111
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
4794111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25366235%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
PubMed ID
25366235
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
4794111
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25366235%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
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