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SLC31 (CTR) family of copper transporters in health and disease
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title
SLC31 (CTR) family of copper transporters in health and disease
(English)
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main subject
clinical chemistry
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copper
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author name string
Heejeong Kim
series ordinal
1
1 reference
stated in
Crossref
Xiaobin Wu
series ordinal
2
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stated in
Crossref
Jaekwon Lee
series ordinal
3
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
2013
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stated in
PubMed
published in
Molecular Aspects of Medicine
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PubMed
volume
34
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stated in
PubMed
issue
2-3
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stated in
PubMed
page(s)
561-70
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stated in
PubMed
cites work
Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake
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Copper Deficiency Myelopathy (Human Swayback)
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21 March 2017
Projection structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture
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21 March 2017
DMT1, a physiologically relevant apical Cu1+ transporter of intestinal cells
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21 March 2017
Biochemical characterization and subcellular localization of human copper transporter 1 (hCTR1)
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21 March 2017
hCTR1: a human gene for copper uptake identified by complementation in yeast
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Metal ion chaperone function of the soluble Cu(I) receptor Atx1.
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21 March 2017
Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transport
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The Saccharomyces cerevisiae copper transport protein (Ctr1p). Biochemical characterization, regulation by copper, and physiologic role in copper uptake.
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21 March 2017
Evidence for Cu(II) reduction as a component of copper uptake by Saccharomyces cerevisiae
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21 March 2017
SLC11 family of H+-coupled metal-ion transporters NRAMP1 and DMT1
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21 March 2017
The SLC31 (Ctr) copper transporter family
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Copper-stimulated endocytosis and degradation of the human copper transporter, hCtr1
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21 March 2017
Characterization of mouse embryonic cells deficient in the ctr1 high affinity copper transporter. Identification of a Ctr1-independent copper transport system
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21 March 2017
Molecular characterization of hCTR1, the human copper uptake protein
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PubMed Central
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21 March 2017
Biochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptake
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PubMed Central
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21 March 2017
Biochemical characterization of the human copper transporter Ctr1
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PubMed Central
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21 March 2017
Characterization of the hCTR1 gene: genomic organization, functional expression, and identification of a highly homologous processed gene
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21 March 2017
Copper metallochaperones
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21 March 2017
Stable plasma membrane levels of hCTR1 mediate cellular copper uptake
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PubMed Central
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21 March 2017
Cisplatin stabilizes a multimeric complex of the human Ctr1 copper transporter: requirement for the extracellular methionine-rich clusters
1 reference
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PubMed Central
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21 March 2017
Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidase
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PubMed Central
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21 March 2017
Identification of methionine-rich clusters that regulate copper-stimulated endocytosis of the human Ctr1 copper transporter
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PubMed Central
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21 March 2017
The copper transporter CTR1 provides an essential function in mammalian embryonic development
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PubMed Central
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21 March 2017
Copper-transporting P-type adenosine triphosphatase (ATP7B) is associated with cisplatin resistance
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21 March 2017
Mammalian copper chaperone Cox17p has an essential role in activation of cytochrome C oxidase and embryonic development
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21 March 2017
The metallochaperone Atox1 plays a critical role in perinatal copper homeostasis
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PubMed Central
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21 March 2017
Mfc1 is a novel forespore membrane copper transporter in meiotic and sporulating cells.
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28 September 2017
Cisplatin binds human copper chaperone Atox1 and promotes unfolding in vitro
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PubMed Central
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28 September 2017
Model peptides provide new insights into the role of histidine residues as potential ligands in human cellular copper acquisition via Ctr1.
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28 September 2017
Acquisition of dietary copper: a role for anion transporters in intestinal apical copper uptake.
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28 September 2017
Ctr1 is an apical copper transporter in mammalian intestinal epithelial cells in vivo that is controlled at the level of protein stability
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28 September 2017
Altered microglial copper homeostasis in a mouse model of Alzheimer's disease
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28 September 2017
C(alpha)-trace model of the transmembrane domain of human copper transporter 1, motion and functional implications
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28 September 2017
Cardiac copper deficiency activates a systemic signaling mechanism that communicates with the copper acquisition and storage organs
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28 September 2017
Metabolic crossroads of iron and copper
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28 September 2017
Copper transporters and the cellular pharmacology of the platinum-containing cancer drugs
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28 September 2017
Regulation of copper transport in Arabidopsis thaliana: a biochemical oscillator?
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PubMed Central
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28 September 2017
Copper transport in mammalian cells: special care for a metal with special needs.
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28 September 2017
Essential transition metal homeostasis in plants
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28 September 2017
Copper transport into the secretory pathway is regulated by oxygen in macrophages
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28 September 2017
SQUAMOSA Promoter Binding Protein-Like7 Is a Central Regulator for Copper Homeostasis in Arabidopsis
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28 September 2017
Deletion of hepatic Ctr1 reveals its function in copper acquisition and compensatory mechanisms for copper homeostasis
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28 September 2017
Copper transport activity of yeast Ctr1 is down-regulated via its C terminus in response to excess copper
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28 September 2017
Transcription factor Sp1 plays an important role in the regulation of copper homeostasis in mammalian cells
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28 September 2017
Metals in Alzheimer's and Parkinson's diseases
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28 September 2017
Mechanisms for copper acquisition, distribution and regulation
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PubMed Central
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28 September 2017
Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation
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28 September 2017
Function and regulation of human copper-transporting ATPases
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PubMed Central
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28 September 2017
The roles of copper transporters in cisplatin resistance
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PubMed Central
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28 September 2017
A structural perspective on copper uptake in eukaryotes
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PubMed Central
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28 September 2017
Activation of superoxide dismutases: putting the metal to the pedal
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PubMed Central
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28 September 2017
The copper transporter (Ctr) family of Cu+ uptake systems.
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PubMed Central
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28 September 2017
Copper transport protein (Ctr1) levels in mice are tissue specific and dependent on copper status
1 reference
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PubMed Central
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28 September 2017
Anticopper therapy against cancer and diseases of inflammation and fibrosis
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PubMed Central
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28 September 2017
Expression profiles of Arabidopsis thaliana in mineral deficiencies reveal novel transporters involved in metal homeostasis.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602788
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28 September 2017
Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals
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PubMed Central
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28 September 2017
Ctr6, a vacuolar membrane copper transporter in Schizosaccharomyces pombe
1 reference
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PubMed Central
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28 September 2017
Ceruloplasmin metabolism and function
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PubMed Central
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28 September 2017
Function, structure, and mechanism of intracellular copper trafficking proteins
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PubMed Central
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28 September 2017
Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development
1 reference
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PubMed Central
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28 September 2017
A delicate balance: homeostatic control of copper uptake and distribution
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PubMed Central
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28 September 2017
Cellular copper transport
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PubMed Central
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28 September 2017
Copper deficiency in humans
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PubMed Central
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28 September 2017
Effects of copper deficiency on the immune system.
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28 September 2017
Dissection of the relative contribution of the Schizosaccharomyces pombe Ctr4 and Ctr5 proteins to the copper transport and cell surface delivery functions
1 reference
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PubMed Central
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31 May 2018
The intracellular Arabidopsis COPT5 transport protein is required for photosynthetic electron transport under severe copper deficiency.
1 reference
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PubMed Central
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28 November 2018
Coordination of platinum therapeutic agents to met-rich motifs of human copper transport protein1.
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PubMed Central
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28 November 2018
Role of copper in angiogenesis and its medicinal implications
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PubMed Central
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28 November 2018
Ctr2 is partially localized to the plasma membrane and stimulates copper uptake in COS-7 cells
1 reference
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PubMed Central
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28 November 2018
Distinct mechanisms for Ctr1-mediated copper and cisplatin transport.
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PubMed Central
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28 November 2018
O-linked glycosylation at threonine 27 protects the copper transporter hCTR1 from proteolytic cleavage in mammalian cells.
1 reference
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PubMed Central
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28 November 2018
The mechanism of copper uptake mediated by human CTR1: a mutational analysis.
1 reference
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PubMed Central
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28 November 2018
Mobilization of intracellular copper stores by the ctr2 vacuolar copper transporter
1 reference
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PubMed Central
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28 November 2018
Eukaryotic CTR copper uptake transporters require two faces of the third transmembrane domain for helix packing, oligomerization, and function.
1 reference
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PubMed Central
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28 November 2018
C-terminal domain of the membrane copper transporter Ctr1 from Saccharomyces cerevisiae binds four Cu(I) ions as a cuprous-thiolate polynuclear cluster: sub-femtomolar Cu(I) affinity of three proteins involved in copper trafficking
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28 November 2018
Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant.
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PubMed Central
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28 November 2018
A widespread transposable element masks expression of a yeast copper transport gene.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3602788
retrieved
28 November 2018
Copper transport and metabolism are normal in aceruloplasminemic mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23506889
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Copper-specific transcriptional repression of yeast genes encoding critical components in the copper transport pathway
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23506889
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Copper-regulatory domain involved in gene expression
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23506889
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23506889
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Human copper transporter hCTR1 mediates basolateral uptake of copper into enterocytes: implications for copper homeostasis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23506889
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.MAM.2012.07.011
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4227062
OpenCitations bibliographic resource ID
4227062
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4227062
PMC publication ID
3602788
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4227062
PubMed publication ID
23506889
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4227062
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