(Q27024191)

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Circulating tumour cells: the evolving concept and the inadequacy of their enrichment by EpCAM-based methodology for basic and clinical cancer research

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Circulating tumour cells: the evolving concept and the inadequacy of their enrichment by EpCAM-based methodology for basic and clinical cancer research (English)

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10 June 2020

Jennifer E Hardingham

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10 June 2020

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P K Grover

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10 June 2020

A G Cummins

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10 June 2020

I C Roberts-Thomson

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August 2014

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Annals of Oncology

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10 June 2020

1506-1516

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10 June 2020

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Detection of EpCAM positive and negative circulating tumor cells in metastatic breast cancer patients

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EpCAM (CD326) finding its role in cancer

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Epithelial-mesenchymal transitions in development and disease

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Systemic spread is an early step in breast cancer

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Epithelial to mesenchymal transition markers expressed in circulating tumour cells of early and metastatic breast cancer patients.

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Circulating tumor cells as a window on metastasis biology in lung cancer

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Circulating tumor cells from patients with advanced prostate and breast cancer display both epithelial and mesenchymal markers

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A novel platform for detection of CK+ and CK- CTCs

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Mesenchymal and stemness circulating tumor cells in early breast cancer diagnosis

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Molecular characterization of circulating tumor cells in human metastatic colorectal cancer

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Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines

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Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

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A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer

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Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients

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Epithelial-mesenchymal transition and stemness features in circulating tumor cells from breast cancer patients.

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https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Expression of stem cell and epithelial-mesenchymal transition markers in primary breast cancer patients with circulating tumor cells

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Molecular markers in circulating tumour cells from metastatic colorectal cancer patients

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Circulating tumor cells with a putative stem cell phenotype in peripheral blood of patients with breast cancer.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Clinical significance of circulating tumor cells, including cancer stem-like cells, in peripheral blood for recurrence and prognosis in patients with Dukes' stage B and C colorectal cancer.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Phosphorylated EGFR and PI3K/Akt signaling kinases are expressed in circulating tumor cells of breast cancer patients

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Detection and characterization of circulating tumor cells in blood of primary breast cancer patients by RT-PCR and comparison to status of bone marrow disseminated cells

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Circulating tumor cells (CTCs) in metastatic breast cancer (MBC): prognosis, drug resistance and phenotypic characterization.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Prognostic Value of EMT-Circulating Tumor Cells in Metastatic Breast Cancer Patients Undergoing High-Dose Chemotherapy with Autologous Hematopoietic Stem Cell Transplantation

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Transcriptome analysis reveals an osteoblast-like phenotype for human osteotropic breast cancer cells

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Detection of EpCAM-Negative and Cytokeratin-Negative Circulating Tumor Cells in Peripheral Blood

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Epithelial-mesenchymal transition and stem cell markers in patients with HER2-positive metastatic breast cancer.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

CD146 expression is associated with a poor prognosis in human breast tumors and with enhanced motility in breast cancer cell lines

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Detection of circulating tumor cells in breast cancer may improve through enrichment with anti-CD146.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Enrichment with anti-cytokeratin alone or combined with anti-EpCAM antibodies significantly increases the sensitivity for circulating tumor cell detection in metastatic breast cancer patients

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Detection of circulating tumor cells in blood of metastatic breast cancer patients using a combination of cytokeratin and EpCAM antibodies

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

CD49f-based selection of circulating tumor cells (CTCs) improves detection across breast cancer subtypes

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Characterization and enumeration of cells secreting tumor markers in the peripheral blood of breast cancer patients.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Isolation of circulating epithelial and tumor progenitor cells with an invasive phenotype from breast cancer patients

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Prognostic value of putative circulating cancer stem cells in patients undergoing hepatic resection for colorectal liver metastasis.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

A dynamic in vivo model of epithelial-to-mesenchymal transitions in circulating tumor cells and metastases of breast cancer

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Demasking of epithelial cell adhesion molecule (EpCAM) on circulating epithelial tumor cells by Tween®20 treatment in breast cancer patients

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

The significance of circulating epithelial cells in Breast Cancer patients by a novel negative selection method

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Negative enrichment of circulating tumor cells using a geometrically activated surface interaction chip

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

HER2-positive circulating tumor cells indicate poor clinical outcome in stage I to III breast cancer patients

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Isolation of tumor cells using size and deformation

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Microdevice for the isolation and enumeration of cancer cells from blood.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Versatile label free biochip for the detection of circulating tumor cells from peripheral blood in cancer patients.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Portable filter-based microdevice for detection and characterization of circulating tumor cells

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

A high-performance microsystem for isolating circulating tumor cells.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Microfluidic flow fractionation device for label-free isolation of circulating tumor cells (CTCs) from breast cancer patients

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Enrichment of cancer cells from whole blood using a microfabricated porous filter

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Analysis of Circulating Tumor Cells in Patients with Non-small Cell Lung Cancer Using Epithelial Marker-Dependent and -Independent Approaches

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Evaluation and Prognostic Significance of Circulating Tumor Cells in Patients With Non–Small-Cell Lung Cancer

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDU018

21 January 2018

Identifiers

10.1093/ANNONC/MDU018

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24651410%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24651410%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

ResearchGate publication ID

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