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Rational development of addiction pharmacotherapies: successes, failures, and prospects
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title
Rational development of addiction pharmacotherapies: successes, failures, and prospects
(English)
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main subject
pharmacotherapy
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author name string
R. Christopher Pierce
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1
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C. P. O'Brien
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2
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P. J. Kenny
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L. J. M. J. Vanderschuren
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4
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language of work or name
English
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publication date
June 2012
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published in
Cold Spring Harbor Perspectives in Medicine
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volume
2
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issue
6
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PubMed
page(s)
a012880
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cites work
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Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction
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Neuroprotective and abstinence-promoting effects of acamprosate: elucidating the mechanism of action
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Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation
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21 March 2017
Attenuation of the euphoric effects of cocaine by the dopamine D1/D5 antagonist ecopipam (SCH 39166)
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PubMed Central
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21 March 2017
Smoking, smoking cessation, and major depression
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21 March 2017
Novel cocaine vaccine linked to a disrupted adenovirus gene transfer vector blocks cocaine psychostimulant and reinforcing effects
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28 September 2017
Aripiprazole maintenance increases smoked cocaine self-administration in humans
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28 September 2017
Treatment of nicotine addiction: present therapeutic options and pipeline developments
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PubMed Central
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28 September 2017
Cocaine-specific antibodies blunt the subjective effects of smoked cocaine in humans
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PubMed Central
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28 September 2017
Controversies in translational research: drug self-administration
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PubMed Central
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28 September 2017
Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction
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28 September 2017
Targeting treatments for alcohol dependence: the pharmacogenetics of naltrexone
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28 September 2017
Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial
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PubMed Central
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28 September 2017
Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial.
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PubMed Central
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28 September 2017
Aripiprazole blocks reinstatement of cocaine seeking in an animal model of relapse
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PubMed Central
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28 September 2017
Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms
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28 September 2017
The mesolimbic dopamine system: the final common pathway for the reinforcing effect of drugs of abuse?
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28 September 2017
Aripiprazole attenuates the discriminative-stimulus and subject-rated effects of D-amphetamine in humans
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28 September 2017
Cocaine Rapid Efficacy Screening Trials (CREST): lessons learned.
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PubMed Central
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28 September 2017
A MEDICAL TREATMENT FOR DIACETYLMORPHINE (HEROIN) ADDICTION. A CLINICAL TRIAL WITH METHADONE HYDROCHLORIDE.
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PubMed Central
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28 September 2017
Clinical and pharmacological evaluation of buprenorphine and naloxone combinations: why the 4:1 ratio for treatment?
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PubMed Central
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28 September 2017
Behavioral effects of cocaine and dopaminergic strategies for preclinical medication development
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PubMed Central
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28 September 2017
Effects of ecopipam, a selective dopamine D1 antagonist, on smoked cocaine self-administration by humans
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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28 September 2017
Bupropion is a nicotinic antagonist.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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28 September 2017
Ethanol and amino acids in the central nervous system: assessment of the pharmacological actions of acamprosate
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PubMed Central
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28 September 2017
Randomised controlled trial of nicotine chewing-gum
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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28 September 2017
An implanted reservoir of morphine solution for rapid induction of physical dependence in rats
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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28 September 2017
Naltrexone in the treatment of alcohol dependence
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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28 September 2017
Is cocaine desire reduced by N-acetylcysteine?
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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31 May 2018
Cystine/glutamate exchange serves as the source for extracellular glutamate: modifications by repeated cocaine administration.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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31 May 2018
Naltrexone, an antagonist for the treatment of heroin dependence. Effects in man.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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31 May 2018
Ability of calcium bis acetyl homotaurine, a GABA agonist, to prevent relapse in weaned alcoholics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
retrieved
31 May 2018
Ethanol preference in the hamster: effects of morphine sulfate and naltrexone, a long-acting morphine antagonist
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
retrieved
31 May 2018
Effect of nicotine chewing gum on smoking behaviour and as an aid to cigarette withdrawal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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31 May 2018
Effects of methadone and morphine maintenance on drug-seeking behavior in the dog
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
retrieved
31 May 2018
Aripiprazole and ropinirole treatment for cocaine dependence: evidence from a pilot study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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28 November 2018
Further observations on the pharmacology of dolophine (methadon, Lilly).
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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28 November 2018
Analgesic activity in compounds related to amidone.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
retrieved
28 November 2018
The alpha4beta2 nicotinic acetylcholine-receptor partial agonist varenicline inhibits both nicotine self-administration following repeated dosing and reinstatement of nicotine seeking in rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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28 November 2018
Tolerance and addiction liability of 6-dimethylamino-4-4-diphenylheptanone-3 (methadon).
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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28 November 2018
An open-label trial of N-acetylcysteine for the treatment of cocaine dependence: a pilot study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
retrieved
28 November 2018
Choice between heroin and food in nondependent and heroin-dependent rhesus monkeys: effects of naloxone, buprenorphine, and methadone
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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28 November 2018
Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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28 November 2018
N-acetyl cysteine-induced blockade of cocaine-induced reinstatement
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
retrieved
28 November 2018
Experimental morphine addiction: method for automatic intravenous injections in unrestrained rats.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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28 November 2018
Instrumental conditioning of jugular self-infusion in the rhesus monkey.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
retrieved
28 November 2018
Evaluation of anti-cocaine antibodies and a cocaine vaccine in a rat self-administration model.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
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28 November 2018
Conversation with Ove Fernö.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
retrieved
28 November 2018
Alteration of ethanol self-administration by naltrexone.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
retrieved
28 November 2018
A homotaurine derivative reduces the voluntary intake of ethanol by rats: are cerebral GABA receptors involved?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3367540
retrieved
28 November 2018
Effects of continuous infusions of SCH 23390 on cocaine- or food-maintained behavior in rhesus monkeys
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22675669
retrieved
12 December 2020
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A substitute for tobacco smoking
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22675669
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Naltrexone and coping skills therapy for alcohol dependence. A controlled study
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22675669
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
MORPHINE SELF-ADMINISTRATION, FOOD-REINFORCED, AND AVOIDANCE BEHAVIORS IN RHESUS MONKEYS
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22675669
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A comparison of sustained-release bupropion and placebo for smoking cessation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22675669
retrieved
12 December 2020
based on heuristic
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Identifiers
DOI
10.1101/CSHPERSPECT.A012880
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PMCID
3367540
1 reference
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PubMed
PubMed ID
22675669
1 reference
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PubMed
ResearchGate publication ID
225276800
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