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Ubiquitination and deubiquitination of REST and its roles in cancers
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scholarly article
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PubMed
title
Ubiquitination and deubiquitination of REST and its roles in cancers
(English)
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main subject
protein ubiquitination
1 reference
based on heuristic
inferred from title
author name string
Zhi Huang
series ordinal
1
1 reference
stated in
Crossref
Shideng Bao
series ordinal
2
1 reference
stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
4 June 2012
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stated in
PubMed
published in
FEBS Letters
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stated in
PubMed
volume
586
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stated in
PubMed
issue
11
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stated in
PubMed
page(s)
1602-5
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stated in
PubMed
cites work
Expression and functions of the repressor element 1 (RE-1)-silencing transcription factor (REST) in breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
REST repression of neuronal genes requires components of the hSWI.SNF complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
CoREST: a functional corepressor required for regulation of neural-specific gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
A splice variant of the neuron-restrictive silencer factor repressor is expressed in small cell lung cancer: a potential role in derepression of neuroendocrine genes and a useful clinical marker
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
Control of chromosome stability by the beta-TrCP-REST-Mad2 axis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
Neuroendocrine-like differentiation of non-small cell lung carcinoma cells: regulation by cAMP and the interaction of mac25/IGFBP-rP1 and 25.1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
Transcriptional regulation: cancer, neurons and the REST
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
A genetic screen for candidate tumor suppressors identifies REST
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
Transcriptional repression by REST: recruitment of Sin3A and histone deacetylase to neuronal genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
21 March 2017
REST regulates oncogenic properties of glioblastoma stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Persistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Retinoic acid induces REST degradation and neuronal differentiation by modulating the expression of SCF(β-TRCP) in neuroblastoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Cancer stem cells in glioblastoma--molecular signaling and therapeutic targeting
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Regulation of the NRSF/REST gene by methylation and CREB affects the cellular phenotype of small-cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
The transcription factor REST is lost in aggressive breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Notch signaling is not essential in sonic hedgehog-activated medulloblastoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
BMP-induced REST regulates the establishment and maintenance of astrocytic identity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
The transcriptional repressor REST/NRSF modulates hedgehog signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Deletion of Atoh1 disrupts Sonic Hedgehog signaling in the developing cerebellum and prevents medulloblastoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Squelching glioblastoma stem cells by targeting REST for proteasomal degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Profiling RE1/REST-mediated histone modifications in the human genome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
SCG3 transcript in peripheral blood is a prognostic biomarker for REST-deficient small cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Nontelomeric TRF2-REST interaction modulates neuronal gene silencing and fate of tumor and stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
REST maintains self-renewal and pluripotency of embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
REST in good times and bad: roles in tumor suppressor and oncogenic activities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Noncoding RNAs in the mammalian central nervous system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Chromatin remodeling in neural development and plasticity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
The many faces of REST oversee epigenetic programming of neuronal genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
No rest for REST: REST/NRSF regulation of neurogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
IB1/JIP-1 controls JNK activation and increased during prostatic LNCaP cells neuroendocrine differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Relaxation of glycine receptor and onconeural gene transcription control in NRSF deficient small cell lung cancer cell lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
28 September 2017
Deubiquitylase HAUSP stabilizes REST and promotes maintenance of neural progenitor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
31 May 2018
Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361610
retrieved
31 May 2018
REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.052
retrieved
21 January 2018
The canonical Wnt pathway directly regulates NRSF/REST expression in chick spinal cord
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.052
retrieved
21 January 2018
Reduced expression of the neuron restrictive silencer factor permits transcription of glycine receptor alpha1 subunit in small-cell lung cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.052
retrieved
21 January 2018
Genetic ablation of a candidate tumor suppressor gene, Rest, does not promote mouse colon carcinogenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.052
retrieved
21 January 2018
The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.04.052
retrieved
21 January 2018
Arginine vasopressin promoter regulation is mediated by a neuron-restrictive silencer element in small cell lung cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22569092
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The neural repressor NRSF/REST binds the PAH1 domain of the Sin3 corepressor by using its distinct short hydrophobic helix
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22569092
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.FEBSLET.2012.04.052
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1893388
OpenCitations bibliographic resource ID
1893388
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1893388
PMC publication ID
3361610
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1893388
PubMed publication ID
22569092
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1893388
ResearchGate publication ID
224925059
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