(Q27028010)

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Agent-based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity

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scholarly article

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19 September 2019

Agent-based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity (English)

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biomedical investigative technique

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19 September 2019

agent-based model

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based on heuristic

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author name string

C. Anthony Hunt

1

1 reference

Ryan C. Kennedy

2

1 reference

Sean H. J. Kim

3

1 reference

Glen E. P. Ropella

4

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language of work or name

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publication date

2013

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4 June 2013

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19 September 2019

Wiley interdisciplinary reviews. Systems biology and medicine

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19 September 2019

5

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4

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461-80

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copyright license

Creative Commons Attribution 2.5 Generic

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Europe PubMed Central

19 September 2019

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MDCK cystogenesis driven by cell stabilization within computational analogues

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CPT: Pharmacometrics and Systems Pharmacology

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The current role of model-based drug development.

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Complexity in a brain-inspired agent-based model

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Use of physiologically based pharmacokinetic modeling for assessment of drug-drug interactions.

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Utility of a physiologically-based pharmacokinetic (PBPK) modeling approach to quantitatively predict a complex drug-drug-disease interaction scenario for rivaroxaban during the drug review process: implications for clinical practice.

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Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs?

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Multiscale mechanistic modeling in pharmaceutical research and development

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Application of PBPK modelling in drug discovery and development at Pfizer

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Have physiologically-based pharmacokinetic models delivered?

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Physiologically based pharmacokinetic modeling: methodology, applications, and limitations with a focus on its role in pediatric drug development

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Agent-based simulation of reactions in the crowded and structured intracellular environment: Influence of mobility and location of the reactants

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At the biological modeling and simulation frontier.

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In silico experiments of existing and hypothetical cytokine-directed clinical trials using agent-based modeling

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28 September 2017

Software agents and the route to the information economy

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Agent-based modeling: a revolution?

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Agent-based model of macrophage action on endocrine pancreas

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Model-based drug development: strengths, weaknesses, opportunities, and threats for broad application of pharmacometrics in drug development.

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21 January 2018

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21 January 2018

Physiologically based synthetic models of hepatic disposition

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21 January 2018

Mechanistic insight from in silico pharmacokinetic experiments: roles of P-glycoprotein, Cyp3A4 enzymes, and microenvironments

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21 January 2018

Tracing multiscale mechanisms of drug disposition in normal and diseased livers

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21 January 2018

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21 January 2018

Individual-Based Modeling of Ecological and Evolutionary Processes

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21 January 2018

Heterogeneous composition of models of computation

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21 January 2018

Combination of process-oriented and pattern-oriented models of land-use change in a mountain area of Vietnam

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21 January 2018

Simulating ancient societies.

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28 November 2018

Can the flow of medicines be improved? Fundamental pharmacokinetic and pharmacological principles toward improving Phase II survival

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agent-based simulation of T-cell activation and proliferation within a lymph node

1 reference

https://pubmed.ncbi.nlm.nih.gov/23737142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifying control mechanisms of granuloma formation during M. tuberculosis infection using an agent-based model

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agent-based modeling of the context dependency in T cell recognition

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based on heuristic

inferred from PubMed ID database lookup

Translational systems biology using an agent-based approach for dynamic knowledge representation: An evolutionary paradigm for biomedical research

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/WSBM.1222

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

release_wi7gbnig4rfvlbamrnnok75pku

0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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