(Q27302422)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

Citrulline a more suitable substrate than arginine to restore NO production and the microcirculation during endotoxemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

3

1 reference

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3 February 2020

author name string

Karolina A P Wijnands

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Hans Vink

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Ernst E van Faassen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Wouter H Lamers

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Wim A Buurman

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Martijn Poeze

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

language of work or name

English

0 references

publication date

29 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

page(s)

e37439

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

3 February 2020

copyright license

start time

29 May 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

How to evaluate the microcirculation: report of a round table conference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Oral citrulline as arginine precursor may be beneficial in sickle cell disease: early phase two results

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Maternal supplementation with citrulline increases renal nitric oxide in young spontaneously hypertensive rats and has long-term antihypertensive effects

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Nitric oxide synthases: Roles, tolls, and controls

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Effects of L-arginine pretreatment on nitric oxide metabolism and hepatosplanchnic perfusion during porcine endotoxemia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Regulation of nitric oxide production in health and disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Pros and cons of L-arginine supplementation in disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Arginine therapy of transgenic-knockout sickle mice improves microvascular function by reducing non-nitric oxide vasodilators, hemolysis, and oxidative stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Arginase blockade protects against hepatic damage in warm ischemia-reperfusion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Arginase: a critical regulator of nitric oxide synthesis and vascular function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Sepsis: an arginine deficiency state?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Mechanisms of inducible nitric oxide synthase (iNOS) inhibition-related improvement of gut mucosal acidosis during hyperdynamic porcine endotoxemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Endothelin receptor antagonist bosentan improves microcirculatory blood flow in splanchnic organs in septic shock

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Reduced arginine availability and nitric oxide production.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Humane endpoints for infectious disease animal models

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

The clinical pharmacology of L-arginine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Nitric oxide and intestinal inflammation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Regulation of intestinal blood flow

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Microcirculatory dysfunction in sepsis: a pathogenetic basis for therapy?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Microcirculatory oxygenation and shunting in sepsis and shock

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Hepatic and splanchnic microvascular responses to inflammation and shock

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Effect of L-arginine or L-citrulline oral supplementation on blood pressure and right ventricular function in heart failure patients with preserved ejection fraction.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Endothelial nitric oxide production is tightly coupled to the citrulline-NO cycle

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Quantifying bedside-derived imaging of microcirculatory abnormalities in septic patients: a prospective validation study

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Argininosuccinate synthase expression is required to maintain nitric oxide production and cell viability in aortic endothelial cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationship

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Gut dysfunction in critically ill patients: a review of the literature.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

The microcirculation unveiled

31 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

Ileal VO(2)-O(2) alterations induced by endotoxin correlate with severity of mitochondrial injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

Effect of prolonged hyperdynamic endotoxemia on jejunal motility in fasted and enterally fed pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

Reduced citrulline availability by OTC deficiency in mice is related to reduced nitric oxide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

Accessibility of endothelial and inducible nitric oxide synthase to the intracellular citrulline-arginine regeneration pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

Time course of nitric oxide production after endotoxin challenge in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

Citrulline modulates muscle protein metabolism in old malnourished rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

Orthogonal polarization spectral imaging: a new method for study of the microcirculation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

Quantitative analysis of small intestinal microcirculation in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

Evaluation of sublingual and gut mucosal microcirculation in sepsis: a quantitative analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

Detection of basal NO production in rat tissues using iron-dithiocarbamate complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

Reduced caloric intake during endotoxemia reduces arginine availability and metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

The role of NOS2 and NOS3 in renal protein and arginine metabolism during early endotoxemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

Adaptative response of nitrogen metabolism in early endotoxemia: role of ornithine aminotransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

L-arginine supplementation in hyperdynamic endotoxemic pigs: effect on nitric oxide synthesis by the different organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

Effects of maternal L-citrulline supplementation on renal function and blood pressure in offspring exposed to maternal caloric restriction: the impact of nitric oxide pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037439

The effect of L-arginine and citrulline on endothelial function in patients in heart failure with preserved ejection fraction.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Effects of L-arginine infusion during ischemia on gut blood perfusion, oxygen tension, and circulating myeloid cell activation in a murine gut ischemia/reperfusion model

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362574

Pharmacokinetics and safety of intravenously administered citrulline in children undergoing congenital heart surgery: Potential therapy for postoperative pulmonary hypertension

28 November 2018

1 reference

12 December 2020

Dietary citrulline but not ornithine counteracts dietary arginine deficiency in rats by increasing splanchnic release of citrulline

1 reference

12 December 2020

Increased microvascular reactivity and improved mortality in septic mice lacking inducible nitric oxide synthase

1 reference

12 December 2020

Nitroglycerin in septic shock after intravascular volume resuscitation

1 reference

12 December 2020

Endotoxemia affects citrulline, arginine and glutamine bioavailability

1 reference

12 December 2020

Rapid routine determination of amino acids in plasma by high-performance liquid chromatography with a 2-3 microns Spherisorb ODS II column

1 reference

12 December 2020

Reduced citrulline production in sepsis is related to diminished de novo arginine and nitric oxide production

1 reference

12 December 2020

In vivo whole body and organ arginine metabolism during endotoxemia (sepsis) is dependent on mouse strain and gender

1 reference

12 December 2020

Renal amino acid metabolism during endotoxemia in the rat

1 reference

12 December 2020

Evidence for intestinal and liver epithelial cell injury in the early phase of sepsis

1 reference

12 December 2020

Nitric oxide precursors and congenital heart surgery: A randomized controlled trial of oral citrulline

1 reference

12 December 2020

Expression of endothelial constitutive nitric oxide synthase mRNA in gastrointestinal mucosa and its downregulation by endotoxin

1 reference

12 December 2020

Effect of endotoxemia on intestinal villus microcirculation in rats

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0037439

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

ADS bibcode

2012PLoSO...737439W

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

22666356

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666356%20AND%20SRC:MED&resulttype=core&format=json