(Q27312503)

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Structural Mechanisms of Mutant Huntingtin Aggregation Suppression by the Synthetic Chaperonin-like CCT5 Complex Explained by Cryoelectron Tomography

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scholarly article

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Europe PubMed Central

26 June 2017

Structural Mechanisms of Mutant Huntingtin Aggregation Suppression by the Synthetic Chaperonin-like CCT5 Complex Explained by Cryoelectron Tomography (English)

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Europe PubMed Central

26 June 2017

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Oksana Sergeeva

2

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12 June 2020

Jesus G Galaz-Montoya

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12 June 2020

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Ralf Langen

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12 June 2020

Michele C Darrow

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12 June 2020

Jose M Isas

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12 June 2020

Jonathan A King

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12 June 2020

Michael F Schmid

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12 June 2020

Wah Chiu

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12 June 2020

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20 May 2015

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26 June 2017

Journal of Biological Chemistry

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12 June 2020

290

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12 June 2020

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12 June 2020

17451-17461

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12 June 2020

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Comparative study of naturally occurring huntingtin fragments in Drosophila points to exon 1 as the most pathogenic species in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498080

21 March 2017

Huntington's disease: the past, present, and future search for disease modifiers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498080

21 March 2017

Huntington's disease genetics

1 reference

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21 March 2017

The crystal structure of the bacterial chaperonin GroEL at 2.8 A

1 reference

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NIH Image to ImageJ: 25 years of image analysis

1 reference

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21 March 2017

EMAN2: an extensible image processing suite for electron microscopy

1 reference

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1 reference

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21 March 2017

Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498080

21 March 2017

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

1 reference

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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

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Automated electron microscope tomography using robust prediction of specimen movements

1 reference

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Pathways of chaperone-mediated protein folding in the cytosol

1 reference

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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

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Single particle tomography in EMAN2

1 reference

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28 September 2017

Polyglutamine- and temperature-dependent conformational rigidity in mutant huntingtin revealed by immunoassays and circular dichroism spectroscopy

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Biochemical characterization of mutants in chaperonin proteins CCT4 and CCT5 associated with hereditary sensory neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498080

28 September 2017

Aberrantly spliced HTT, a new player in Huntington's disease pathogenesis

1 reference

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28 September 2017

TRiC's tricks inhibit huntingtin aggregation

1 reference

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28 September 2017

Pharmacological protein targets in polyglutamine diseases: mutant polypeptides and their interactors

1 reference

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Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers

1 reference

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Opportunities and challenges for molecular chaperone modulation to treat protein-conformational brain diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498080

28 September 2017

Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes

1 reference

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28 September 2017

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease

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28 September 2017

Putting huntingtin "aggregation" in view with windows into the cellular milieu.

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28 September 2017

Folding of large multidomain proteins by partial encapsulation in the chaperonin TRiC/CCT.

1 reference

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1 reference

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Protein aggregates in Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498080

28 September 2017

Mutant huntingtin fragments form oligomers in a polyglutamine length-dependent manner in vitro and in vivo

1 reference

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The chaperonin TRiC controls polyglutamine aggregation and toxicity through subunit-specific interactions

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1 reference

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In vivo newly translated polypeptides are sequestered in a protected folding environment

1 reference

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The role of molecular chaperones in protein folding

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1 reference

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Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers.

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Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state.

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1 reference

https://pubmed.ncbi.nlm.nih.gov/25995452

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10.1074/JBC.M115.655373

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Europe PubMed Central

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12 June 2020

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Europe PubMed Central

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12 June 2020

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12 June 2020

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