(Q27321643)

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Sequential alterations in catabolic and anabolic gene expression parallel pathological changes during progression of monoiodoacetate-induced arthritis

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scholarly article

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Sequential alterations in catabolic and anabolic gene expression parallel pathological changes during progression of monoiodoacetate-induced arthritis (English)

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author name string

Jin Nam

1

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Priyangi Perera

2

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Jie Liu

3

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Bjoern Rath

4

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James Deschner

5

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Robert Gassner

6

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Timothy A Butterfield

7

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Sudha Agarwal

8

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language of work or name

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publication date

2011

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6

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9

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e24320

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copyright license

Creative Commons Attribution 4.0 International

13 September 2011

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April 2022 Public Data File from Crossref

copyright status

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Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte

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Synthesis of classical pathway complement components by chondrocytes

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Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks

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Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis

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Transcriptome-wide gene regulation by gentle treadmill walking during the progression of monoiodoacetate-induced arthritis

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DAMPening inflammation by modulating TLR signalling

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Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc

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Prostaglandin E2 and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis

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Mouse models and new therapeutic targets for OA.

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Translational research in osteoarthritis--from molecules to animals to humans.

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28 September 2017

Differential transcriptome analysis of intraarticular lesional vs intact cartilage reveals new candidate genes in osteoarthritis pathophysiology

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28 September 2017

Immunobiology of the TAM receptors

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28 September 2017

Medical care expenditures and earnings losses among persons with arthritis and other rheumatic conditions in 2003, and comparisons with 1997

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28 September 2017

Mutation analysis of candidate genes within the 2q33.3 linkage area for familial early-onset generalised osteoarthritis.

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28 September 2017

Pathobiology of osteoarthritis: pathomechanisms and potential therapeutic targets

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Metabolic activity of chondrocytes in human osteoarthritis as a result of cell-extracellular matrix interactions

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28 September 2017

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21 January 2018

Altered patterns and synthesis of extracellular matrix macromolecules in early osteoarthritis

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Autocrine production of IL-1 beta by human osteoarthritis-affected cartilage and differential regulation of endogenous nitric oxide, IL-6, prostaglandin E2, and IL-8.

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28 September 2017

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28 September 2017

Structural and metabolic changes in articular cartilage induced by iodoacetate

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28 September 2017

Osteoarthritis cartilage histopathology: grading and staging.

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21 January 2018

Comparative analysis of gene expression profiles in intact and damaged regions of human osteoarthritic cartilage.

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21 January 2018

Summary of the OA biomarkers workshop 2009--biochemical biomarkers: biology, validation, and clinical studies.

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A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models.

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Evaluation of pain behavior and bone destruction in two arthritic models in guinea pig and rat.

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21 January 2018

Mono-Iodoacetate-Induced Histologic Changes in Subchondral Bone and Articular Cartilage of Rat Femorotibial Joints: An Animal Model of Osteoarthritis

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21 January 2018

Mono-iodoacetate-induced experimental osteoarthritis: a dose-response study of loss of mobility, morphology, and biochemistry.

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21 January 2018

Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis

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Pain related behaviour in two models of osteoarthritis in the rat knee

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Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis

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Production of the chemokine RANTES by articular chondrocytes and role in cartilage degradation

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Identification and location of bone-forming cells within cartilage canals on their course into the secondary ossification centre.

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21 January 2018

Comparative analysis of gene expression profiles between primary knee osteoarthritis and an osteoarthritis endemic to Northwestern China, Kashin-Beck disease

1 reference

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21 January 2018

Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0024320

21 January 2018

Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis.

1 reference

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Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI.

1 reference

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21 January 2018

Gene expression in human chondrocytes in late osteoarthritis is changed in both fibrillated and intact cartilage without evidence of generalised chondrocyte hypertrophy.

1 reference

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21 January 2018

Biosynthesis of the vitamin K-dependent matrix Gla protein (MGP) in chondrocytes: a fetuin-MGP protein complex is assembled in vesicles shed from normal but not from osteoarthritic chondrocytes

1 reference

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21 January 2018

A Cluster Separation Measure

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21 January 2018

A cluster separation measure.

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28 November 2018

Modern molecular analysis of a traditional disease: progression in osteoarthritis

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Global analyses of gene expression in early experimental osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21931681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is the response of cartilage to injury relevant to osteoarthritis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21931681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips

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12 December 2020

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inferred from PubMed ID database lookup

Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt-16 expression and signaling after injury and in osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21931681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunolocalization of MMP-19 in the human intervertebral disc: implications for disc aging and degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/21931681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21931681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large-scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21931681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anabolic and catabolic gene expression pattern analysis in normal versus osteoarthritic cartilage using complementary DNA-array technology

1 reference

https://pubmed.ncbi.nlm.nih.gov/21931681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular cell adhesion molecule 1 as a predictor of severe osteoarthritis of the hip and knee joints

1 reference

https://pubmed.ncbi.nlm.nih.gov/21931681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0024320

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2011PLoSO...624320N

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