(Q27321768)

2

0 references

Christina L Roland

3

0 references

Jason E Toombs

4

0 references

Mari Nyquist-Andersen

5

0 references

Anita Kavlie

6

0 references

Kyle Schlunegger

7

0 references

James A Richardson

8

0 references

Rolf A Brekken

Creative Commons Attribution 4.0 International

9

0 references

language of work or name

English

0 references

publication date

2010

0 references

published in

PLOS One

0 references

volume

5

0 references

issue

8

0 references

page(s)

e12031

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copyright license

start time

6 August 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

21 March 2017

1 reference

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VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

21 March 2017

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VEGF-Trap: a VEGF blocker with potent antitumor effects

21 March 2017

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Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor

21 March 2017

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Tumor angiogenesis: therapeutic implications

21 March 2017

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Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling

21 March 2017

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Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide

21 March 2017

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Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

21 March 2017

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Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

21 March 2017

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Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

21 March 2017

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Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis

7 April 2017

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

7 April 2017

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PlGF blockade does not inhibit angiogenesis during primary tumor growth

7 April 2017

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Cytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer

28 September 2017

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Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression

28 September 2017

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Targeting angiogenesis: progress with anti-VEGF treatment with large molecules

28 September 2017

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Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts.

28 September 2017

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Experience with irinotecan for the treatment of malignant glioma

28 September 2017

1 reference

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The molecular basis of class side effects due to treatment with inhibitors of the VEGF/VEGFR pathway

28 September 2017

1 reference

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Antibody-based therapy for solid tumors

28 September 2017

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Anti-VEGF-A therapy reduces lymphatic vessel density and expression of VEGFR-3 in an orthotopic breast tumor model

28 September 2017

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Mechanisms of adverse effects of anti-VEGF therapy for cancer

28 September 2017

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Mice expressing a humanized form of VEGF-A may provide insights into the safety and efficacy of anti-VEGF antibodies

28 September 2017

1 reference

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Vascular endothelial growth factor (VEGF) signaling in tumor progression

28 September 2017

1 reference

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Targeting the vascular endothelial growth factor pathway in the treatment of human malignancy.

28 September 2017

1 reference

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Anti-vascular endothelial growth factor receptor-1 antagonist antibody as a therapeutic agent for cancer

28 September 2017

1 reference

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The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma

28 September 2017

1 reference

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Placenta growth factor overexpression inhibits tumor growth, angiogenesis, and metastasis by depleting vascular endothelial growth factor homodimers in orthotopic mouse models

28 September 2017

1 reference

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Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A

28 September 2017

1 reference

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Lessons from phase III clinical trials on anti-VEGF therapy for cancer

28 September 2017

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Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF.

28 September 2017

1 reference

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VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis

28 September 2017

1 reference

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Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation.

28 September 2017

1 reference

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The vascular endothelial growth factor (VEGF) receptor Flt-1 (VEGFR-1) modulates Flk-1 (VEGFR-2) signaling during blood vessel formation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917360

VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917360

Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

28 September 2017

1 reference

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Evaluation of Novel Antimouse VEGFR2 Antibodies as Potential Antiangiogenic or Vascular Targeting Agents for Tumor Therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917360

Expression of soluble VEGF receptor 2 and characterization of its binding by surface plasmon resonance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917360

Vascular endothelial growth factor as a marker of tumor endothelium.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917360

Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into orthotopic pancreatic tumors in mice.

31 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012031

Novel Phase I dose de-escalation design trial to determine the biological modulatory dose of the antiangiogenic agent SU5416.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012031

Placenta growth factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PlGF-1/VEGF heterodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012031

VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012031

Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917360

Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of a humanized monoclonal antibody against vascular endothelial growth factor.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917360

Direct evidence for endothelial vascular endothelial growth factor receptor-1 function in nitric oxide-mediated angiogenesis

28 November 2018

1 reference

12 December 2020

Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice

1 reference

12 December 2020

Molecular Imaging and Biological Evaluation of HuMV833 Anti-VEGF Antibody: Implications for Trial Design of Antiangiogenic Antibodies

1 reference

12 December 2020

MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis

1 reference

12 December 2020

A monoclonal antibody that blocks VEGF binding to VEGFR2 (KDR/Flk-1) inhibits vascular expression of Flk-1 and tumor growth in an orthotopic human breast cancer model

1 reference

12 December 2020