(Q27339846)

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Comparison of (64)Cu-complexing bifunctional chelators for radioimmunoconjugation: labeling efficiency, specific activity, and in vitro/in vivo stability

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 June 2017

Comparison of (64)Cu-complexing bifunctional chelators for radioimmunoconjugation: labeling efficiency, specific activity, and in vitro/in vivo stability (English)

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Europe PubMed Central

PubMed publication ID

26 June 2017

organic chemistry

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author name string

Maggie S Cooper

1

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Europe PubMed Central

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26 June 2017

Michelle T Ma

2

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Europe PubMed Central

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26 June 2017

Kavitha Sunassee

3

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Europe PubMed Central

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26 June 2017

Karen P Shaw

4

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Europe PubMed Central

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26 June 2017

Jennifer D Williams

5

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Europe PubMed Central

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26 June 2017

Rowena L Paul

6

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Europe PubMed Central

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26 June 2017

Paul S Donnelly

7

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Europe PubMed Central

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26 June 2017

Philip J Blower

8

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Europe PubMed Central

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26 June 2017

language of work or name

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publication date

13 April 2012

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Europe PubMed Central

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26 June 2017

Bioconjugate Chemistry

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Europe PubMed Central

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26 June 2017

23

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Europe PubMed Central

PubMed publication ID

26 June 2017

5

1 reference

Europe PubMed Central

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26 June 2017

1029-1039

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Gallium-68 complex of a macrobicyclic cage amine chelator tethered to two integrin-targeting peptides for diagnostic tumor imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Development and validation of the 57Co assay for determining the ligand to antibody ratio in bifunctional chelate/antibody conjugates for use in radioimmunotherapy

1 reference

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29 September 2017

PET of somatostatin receptor-positive tumors using 64Cu- and 68Ga-somatostatin antagonists: the chelate makes the difference

1 reference

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29 September 2017

A novel tetrabranched neurotensin(8-13) cyclam derivative: synthesis, 64Cu-labeling and biological evaluation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

In vitro and in vivo evaluation of 64Cu-labeled SarAr-bombesin analogs in gastrin-releasing peptide receptor-expressing prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Biological stability evaluation of the α2β1 receptor imaging agents: diamsar and DOTA conjugated DGEA peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Imaging cancer using PET--the effect of the bifunctional chelator on the biodistribution of a (64)Cu-labeled antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Peptide targeted copper-64 radiopharmaceuticals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Evaluation of Copper-64 Labeled AmBaSar Conjugated Cyclic RGD Peptide for Improved MicroPET Imaging of Integrin αvβ3 Expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Comparison of bifunctional chelates for (64)Cu antibody imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Comparative evaluation of three 64Cu-labeled E. coli heat-stable enterotoxin analogues for PET imaging of colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Imaging and biodistribution of Her2/neu expression in non-small cell lung cancer xenografts with Cu-labeled trastuzumab PET.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Molecular imaging of cancer with copper-64 radiopharmaceuticals and positron emission tomography (PET).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Evaluation of [64Cu]Cu-DOTA and [64Cu]Cu-CB-TE2A chelates for targeted positron emission tomography with an alphavbeta6-specific peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Receptor-binding, biodistribution, and metabolism studies of 64Cu-DOTA-cetuximab, a PET-imaging agent for epidermal growth-factor receptor-positive tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Bifunctional chelates for metal nuclides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Positron emission tomography (PET) imaging of neuroblastoma and melanoma with 64Cu-SarAr immunoconjugates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

[64Cu-NOTA-8-Aoc-BBN(7-14)NH2] targeting vector for positron-emission tomography imaging of gastrin-releasing peptide receptor-expressing tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

The long and short of it: the influence of N-carboxyethyl versusN-carboxymethyl pendant arms on in vitro and in vivo behavior of copper complexes of cross-bridged tetraamine macrocycles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Quantitative PET of EGFR expression in xenograft-bearing mice using 64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

In vitro and in vivo characterization of 64Cu-labeled Abegrin, a humanized monoclonal antibody against integrin alpha v beta 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Molecular imaging with copper-64.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

In vivo transchelation of copper-64 from TETA-octreotide to superoxide dismutase in rat liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Comparison of four 64Cu-labeled somatostatin analogues in vitro and in a tumor-bearing rat model: evaluation of new derivatives for positron emission tomography imaging and targeted radiotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Copper radionuclides and radiopharmaceuticals in nuclear medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Radioimmunotherapy with a 64Cu-labeled monoclonal antibody: a comparison with 67Cu.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Macrocyclic chelates of radiometals for diagnosis and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

29 September 2017

Transfer of copper from a chelated 67Cu-antibody conjugate to ceruloplasmin in lymphoma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

2 June 2018

Cellular processing of copper-67-labeled monoclonal antibody chCE7 by human neuroblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

2 June 2018

Conjugation of antibodies with bifunctional chelating agents: isothiocyanate and bromoacetamide reagents, methods of analysis, and subsequent addition of metal ions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

2 June 2018

Comparative biodistribution studies of DTPA-derivative bifunctional chelates for radiometal labeled monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

2 June 2018

Similarity of copper and technetium binding sites in human IgG

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

2 June 2018

Hexadentate bispidine derivatives as versatile bifunctional chelate agents for copper(II) radioisotopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

Evaluation of novel bifunctional chelates for the development of Cu-64-based radiopharmaceuticals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

Imaging and pharmacokinetics of (64)Cu-DOTA-HB22.7 administered by intravenous, intraperitoneal, or subcutaneous injection to mice bearing non-Hodgkin's lymphoma xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

Transfer of copper between bis(thiosemicarbazone) ligands and intracellular copper-binding proteins. insights into mechanisms of copper uptake and hypoxia selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

Synthesis, Copper(II) Complexation, (64)Cu-Labeling, and Bioconjugation of a New Bis(2-pyridylmethyl) Derivative of 1,4,7-Triazacyclononane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

New 64Cu PET imaging agents for personalised medicine and drug development using the hexa-aza cage, SarAr.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

Comparative in vivo stability of copper-64-labeled cross-bridged and conventional tetraazamacrocyclic complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

In vivo evaluation of pretargeted 64Cu for tumor imaging and therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

Targeting of renal carcinoma with 67/64Cu-labeled anti-L1-CAM antibody chCE7: selection of copper ligands and PET imaging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

Conjugation of monoclonal antibodies with TETA using activated esters: biological comparison of 64Cu-TETA-1A3 with 64Cu-BAT-2IT-1A3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

Radiolabeling and in vivo behavior of copper-64-labeled cross-bridged cyclam ligands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

Carboxymethylated cage amines: coordination and lactamization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

An improved method for conjugating monoclonal antibodies with N-hydroxysulfosuccinimidyl DOTA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

A comparative study of copper-67 radiolabeling and kinetic stabilities of antibody-macrocycle chelate conjugates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

Preparation, biodistribution and dosimetry of copper-64-labeled anti-colorectal carcinoma monoclonal antibody fragments 1A3-F(ab')2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4756438

27 November 2018

Preclinical evaluation of 67Cu-labeled intact and fragmented anti-colon carcinoma monoclonal antibody MAb35

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Labeling of antibodies with 64Cu using a conjugate containing a macrocyclic amine chelating agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stability and Structure of Activated Macrocycles. Ligands with Biological Applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A convenient synthesis of novel bifunctional prochelators for coupling to bioactive peptides for radiometal labelling

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody labeling with copper-67 using the bifunctional macrocycle 4-[(1,4,8,11-tetraazacyclotetradec-1-yl)methyl]benzoic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carboxymethylation of cage amines: control of alkylation by metal ion coordination

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of Four Bifunctional Chelates for Radiolabeling Monoclonal Antibodies with Copper Radioisotopes: Biodistribution and Metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conjugation of chelating agents to proteins and radiolabeling with trivalent metallic isotopes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of coordination chemistry in the development of copper and rhenium radiopharmaceuticals

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum stability of 67Cu chelates: comparison with 111In and 57Co

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The in vivo behavior of copper-64-labeled azamacrocyclic complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiometal-labeled agents (non-technetium) for diagnostic imaging

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of 2-(p-thiocyanatobenzyl)-1,4,7-triazacyclononane-1,4,7-triacetic acid: application of the 4-methoxy-2,3,6-trimethylbenzenesulfonamide protecting group in the synthesis of macrocyclic polyamines

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrobicyclic cage amine ligands for copper radiopharmaceuticals: a single bivalent cage amine containing two Lys3-bombesin targeting peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Copper-64-labeled antibodies for PET imaging

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of linker chemistry on the pharmacokinetics of radioimmunoconjugates

1 reference

https://pubmed.ncbi.nlm.nih.gov/22471317

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BC300037W

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

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