(Q27547434)

English

Est1p YLR233C

fungal protein found in Saccharomyces cerevisiae S288c

EST1
YLR233C
Est1p

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

10 December 2016

Tetratricopeptide-like helical domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17214

DNA/RNA-binding domain, Est1-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Telomerase activating protein Est1 family

1 reference

based on heuristic

inferred from protein domain or family

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

single-stranded DNA binding

determination method

1 reference

8 April 2019

Est1 has the properties of a single-stranded telomere end-binding protein

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

telomeric DNA binding

determination method

1 reference

27 February 2018

Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

determination method

determination method

1 reference

8 April 2019

A bulged stem tethers Est1p to telomerase RNA in budding yeast

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

ribonuclease activity

determination method

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

determination method

protein binding

determination method

6 references

8 April 2019

Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

8 April 2019

Telomerase RNA TLC1 shuttling to the cytoplasm requires mRNA export factors and is important for telomere maintenance

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

8 April 2019

The nuclear envelope and spindle pole body-associated Mps3 protein bind telomere regulators and function in telomere clustering

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

8 April 2019

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

8 April 2019

Proteasome-dependent degradation of Est1p regulates the cell cycle-restricted assembly of telomerase in Saccharomyces cerevisiae

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

8 April 2019

The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

ribonucleoprotein complex binding

determination method

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

determination method

telomerase RNA binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

determination method

1 reference

8 April 2019

Intracellular trafficking of yeast telomerase components.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

telomerase holoenzyme complex

determination method

3 references

1 January 2018

The Est3 protein is a subunit of yeast telomerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

1 January 2018

The Est3 protein is a subunit of yeast telomerase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

biological process

telomere maintenance

determination method

1 reference

8 April 2019

A mutant with a defect in telomere elongation leads to senescence in yeast

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

telomere maintenance via telomerase

determination method

3 references

27 February 2018

The Est3 protein is a subunit of yeast telomerase

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

determination method

27 February 2018

Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

determination method

27 February 2018

The Est3 protein is a subunit of yeast telomerase

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

determination method

G-quadruplex DNA formation

determination method

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

determination method

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

determination method

mRNA export from nucleus

determination method

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

determination method

regulation of telomere maintenance via telomerase

determination method

1 reference

7 November 2018

Modulation of yeast telomerase activity by Cdc13 and Est1 in vitro

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

determination method

regulation of RNA stability

determination method

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

determination method

RNA phosphodiester bond hydrolysis

determination method

1 reference

7 November 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17214&geneProductId=UniProtKB:P17214

determination method

telomere maintenance via telomerase

determination method

4 references

8 April 2019

The Est3 protein is a subunit of yeast telomerase

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

8 April 2019

Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

8 April 2019

The Est3 protein is a subunit of yeast telomerase

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17214

determination method

Telomerase activating protein Est1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17214

DNA/RNA-binding domain, Est1-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17214

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Saccharomyces Genome Database ID

1 reference

20 March 2022

Sitelinks

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