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Transcription regulator CYC8 YBR112C
fungal protein found in Saccharomyces cerevisiae S288c
YBR112C
CYC8
transcription regulator CYC8
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P14922
subclass of
protein
1 reference
stated in
UniProt
retrieved
19 January 2017
UniProt protein ID
P14922
part of
Tetratricopeptide-like helical domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P14922
Tetratricopeptide repeat-containing domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Tetratricopeptide repeat 1 family
1 reference
based on heuristic
inferred from protein domain or family
Tetratricopeptide repeat family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Saccharomyces cerevisiae S288c
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P14922
encoded by
CYC8
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P14922
molecular function
histone deacetylase binding
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IDA
protein binding
determination method
IPI
7 references
retrieved
9 May 2019
stated in
An in vivo map of the yeast protein interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IPI
retrieved
9 May 2019
stated in
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IPI
retrieved
9 May 2019
stated in
Ssn6-Tup1 interacts with class I histone deacetylases required for repression
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IPI
retrieved
9 May 2019
stated in
The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IPI
retrieved
9 May 2019
stated in
Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IPI
retrieved
9 May 2019
stated in
Proteome survey reveals modularity of the yeast cell machinery
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IPI
retrieved
9 May 2019
stated in
Hrs1/Med3 is a Cyc8-Tup1 corepressor target in the RNA polymerase II holoenzyme.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IPI
transcription coactivator activity
determination method
IDA
IGI
IPI
3 references
retrieved
9 May 2019
stated in
The Tup1-Cyc8 protein complex can shift from a transcriptional co-repressor to a transcriptional co-activator.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IPI
retrieved
9 May 2019
stated in
The Tup1-Cyc8 protein complex can shift from a transcriptional co-repressor to a transcriptional co-activator.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IGI
retrieved
9 May 2019
stated in
The Tup1-Cyc8 protein complex can shift from a transcriptional co-repressor to a transcriptional co-activator.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IDA
transcription corepressor activity
determination method
IDA
IPI
2 references
retrieved
9 May 2019
stated in
The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IPI
retrieved
9 May 2019
stated in
The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IDA
cell component
transcription repressor complex
determination method
IPI
1 reference
retrieved
21 June 2018
stated in
A complex composed of tup1 and ssn6 represses transcription in vitro
GOA
curator
SGD
Saccharomyces Genome Database ID
S000000316
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14922&geneProductId=UniProtKB:P14922
determination method
IPI
nucleus
determination method
IDA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P14922
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IEA
retrieved
9 May 2019
stated in
Ssn6-Tup1 is a general repressor of transcription in yeast
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IDA
transcription repressor complex
determination method
IBA
IPI
2 references
retrieved
9 May 2019
stated in
A complex composed of tup1 and ssn6 represses transcription in vitro
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IPI
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IBA
biological process
negative regulation of transcription by RNA polymerase II
determination method
IMP
2 references
retrieved
9 May 2019
stated in
The Tup1-Ssn6 general repressor is involved in repression of IME1 encoding a transcriptional activator of meiosis in Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IMP
retrieved
9 May 2019
stated in
Repressors and upstream repressing sequences of the stress-regulated ENA1 gene in Saccharomyces cerevisiae: bZIP protein Sko1p confers HOG-dependent osmotic regulation
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IMP
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P14922
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14922&geneProductId=UniProtKB:P14922
determination method
IEA
chromatin remodeling
determination method
IGI
1 reference
retrieved
9 May 2019
stated in
Nhp6 facilitates Aft1 binding and Ssn6 recruitment, both essential for FRE2 transcriptional activation
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IGI
regulation of response to DNA damage stimulus
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IMP
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P14922
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14922&geneProductId=UniProtKB:P14922
determination method
IEA
transcription by RNA polymerase II
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P14922&geneProductId=UniProtKB:P14922
determination method
IEA
positive regulation of transcription by RNA polymerase II
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Yeast Cyc8p and Tup1p proteins function as coactivators for transcription of Stp1/2p-dependent amino acid transporter genes
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14922
determination method
IMP
has part(s)
Tetratricopeptide repeat-containing domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P14922
tetratricopeptide repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P14922
Tetratricopeptide repeat 1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P14922
Identifiers
RefSeq protein ID
NP_009670
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
852410
UniProt protein ID
P14922
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P14922
Ensembl protein ID
YBR112C
1 reference
stated in
ensembl Release 106
Ensembl protein ID
YBR112C
Saccharomyces Genome Database ID
S000000316
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
852410
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