(Q27548091)

English

Centromeric DNA-binding histone H3-like protein CSE4 YKL049C

fungal protein found in Saccharomyces cerevisiae S288c

centromeric DNA-binding histone H3-like protein CSE4
CSE4
YKL049C

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Statements

1 reference

25 May 2022

1 reference

19 January 2017

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P36012

Histone H3/CENP-A

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P36012

Histone H2A/H2B/H3, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

centromeric DNA binding

determination method or standard

IDA

sequence-specific DNA binding

determination method or standard

IDA

1 reference

retrieved

9 May 2019

stated in

The centromere-specific histone variant Cse4p (CENP-A) is essential for functional chromatin architecture at the yeast 2-microm circle partitioning locus and promotes equal plasmid segregation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IDA

protein heterodimerization activity

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IEA

protein binding

determination method or standard

IPI

5 references

retrieved

9 May 2019

stated in

The yeast RSC chromatin-remodeling complex is required for kinetochore function in chromosome segregation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IPI

retrieved

9 May 2019

stated in

Scm3, an essential Saccharomyces cerevisiae centromere protein required for G2/M progression and Cse4 localization

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IPI

retrieved

9 May 2019

stated in

Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IPI

retrieved

9 May 2019

stated in

Defining the budding yeast chromatin-associated interactome

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IPI

retrieved

9 May 2019

stated in

Recognition of the centromere-specific histone Cse4 by the chaperone Scm3

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IPI

nucleosomal DNA binding

determination method or standard

IBA

1 reference

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IBA

cell component

chromosome

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IEA

nucleus

determination method or standard

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36012&geneProductId=UniProtKB:P36012

determination method or standard

IEA

CENP-A containing nucleosome

determination method or standard

IDA

kinetochore

determination method or standard

3 references

9 May 2019

The N terminus of the centromere H3-like protein Cse4p performs an essential function distinct from that of the histone fold domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IEA

retrieved

9 May 2019

stated in

Bub1 kinase and Sgo1 modulate pericentric chromatin in response to altered microtubule dynamics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IDA

nucleosome

determination method or standard

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36012&geneProductId=UniProtKB:P36012

determination method or standard

IEA

chromosome, centromeric region

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IEA

2-micrometer circle DNA

determination method or standard

IDA

1 reference

retrieved

9 May 2019

stated in

The centromere-specific histone variant Cse4p (CENP-A) is essential for functional chromatin architecture at the yeast 2-microm circle partitioning locus and promotes equal plasmid segregation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IDA

biological process

mitotic sister chromatid segregation

determination method or standard

IMP

1 reference

retrieved

9 May 2019

stated in

A mutation in CSE4, an essential gene encoding a novel chromatin-associated protein in yeast, causes chromosome nondisjunction and cell cycle arrest at mitosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IMP

2-micrometer plasmid partitioning

determination method or standard

IMP

1 reference

retrieved

9 May 2019

stated in

The centromere-specific histone variant Cse4p (CENP-A) is essential for functional chromatin architecture at the yeast 2-microm circle partitioning locus and promotes equal plasmid segregation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IMP

nucleosome assembly

determination method or standard

IBA

1 reference

retrieved

1 January 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P36012&geneProductId=UniProtKB:P36012

determination method or standard

IBA

protein localization to CENP-A containing chromatin

determination method or standard

IMP

1 reference

retrieved

9 May 2019

stated in

Budding yeast CENP-ACse4 interacts with the N-terminus of Sgo1 and regulates its association with centromeric chromatin.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IMP

rRNA transcription

determination method or standard

IBA

1 reference

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

IBA

kinetochore assembly

determination method or standard

IMP

1 reference

retrieved

9 May 2019

stated in

De novo kinetochore assembly requires the centromeric histone H3 variant.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P36012

determination method or standard

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P36012

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

Saccharomyces Genome Database ID

1 reference

20 March 2022

(Q27548091)

Centromeric DNA-binding histone H3-like protein CSE4 YKL049C

Statements

Identifiers

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