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DNA repair protein SMC6 YLR383W
fungal protein found in Saccharomyces cerevisiae S288c
DNA repair protein SMC6
YLR383W
SMC6
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q12749
subclass of
protein
1 reference
stated in
NCBI Gene
retrieved
10 December 2016
Entrez Gene ID
851099
part of
Rad50/SbcC-type AAA domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Saccharomyces cerevisiae S288c
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q12749
encoded by
SMC6
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q12749
molecular function
ATP binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q12749
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IEA
SUMO transferase activity
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IDA
nucleotide binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q12749
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IEA
damaged DNA binding
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Chromosomal association of the Smc5/6 complex reveals that it functions in differently regulated pathways
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IDA
protein binding
determination method
IPI
1 reference
retrieved
9 May 2019
stated in
Identification of a novel non-structural maintenance of chromosomes (SMC) component of the SMC5-SMC6 complex involved in DNA repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IPI
cell component
nucleus
determination method
IDA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q12749
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IEA
retrieved
9 May 2019
stated in
Identification of a novel non-structural maintenance of chromosomes (SMC) component of the SMC5-SMC6 complex involved in DNA repair
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IDA
chromosome
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q12749
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IEA
site of double-strand break
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IDA
Smc5-Smc6 complex
determination method
IDA
IEA
2 references
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IEA
retrieved
9 May 2019
stated in
A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IDA
mitochondrion
determination method
HDA
2 references
retrieved
9 May 2019
stated in
Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
HDA
retrieved
9 May 2019
stated in
The proteome of Saccharomyces cerevisiae mitochondria
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
HDA
biological process
double-strand break repair via homologous recombination
determination method
IMP
IEA
2 references
retrieved
9 May 2019
stated in
Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IMP
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IEA
DNA repair
determination method
IMP
IDA
IEA
4 references
retrieved
9 May 2019
stated in
A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IMP
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q12749
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IEA
retrieved
9 May 2019
stated in
Identification of a novel non-structural maintenance of chromosomes (SMC) component of the SMC5-SMC6 complex involved in DNA repair
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IDA
DNA recombination
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q12749
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IEA
DNA double-strand break attachment to nuclear envelope
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
PolySUMOylation by Siz2 and Mms21 triggers relocation of DNA breaks to nuclear pores through the Slx5/Slx8 STUbL.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IMP
cellular response to DNA damage stimulus
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q12749
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IEA
chromosome separation
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
SMC5 and SMC6 genes are required for the segregation of repetitive chromosome regions.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IMP
protein sumoylation
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IEA
resolution of recombination intermediates
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Sumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12749
determination method
IMP
has part(s)
Rad50/SbcC-type AAA domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q12749
Identifiers
RefSeq protein ID
NP_013487
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
851099
UniProt protein ID
Q12749
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q12749
Ensembl protein ID
YLR383W
1 reference
stated in
ensembl Release 106
Ensembl protein ID
YLR383W
Saccharomyces Genome Database ID
S000004375
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
851099
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