(Q27548439)

http://www.ebi.ac.uk/interpro/protein/P14737

Rad9-like Rad53-binding domain, fungi, protein family

1 reference

based on heuristic

inferred from protein domain or family

BRCT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

double-stranded DNA binding

1 reference

9 May 2019

The checkpoint Saccharomyces cerevisiae Rad9 protein contains a tandem tudor domain that recognizes DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

enzyme activator activity

IDA

1 reference

9 May 2019

Use of quantitative mass spectrometric analysis to elucidate the mechanisms of phospho-priming and auto-activation of the checkpoint kinase Rad53 in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

1 reference

27 February 2018

Rad9 BRCT domain interaction with phosphorylated H2AX regulates the G1 checkpoint in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?protein=P14737&geneProductId=UniProtKB:P14737

7 references

9 May 2019

CDC5 inhibits the hyperphosphorylation of the checkpoint kinase Rad53, leading to checkpoint adaptation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

9 May 2019

DNA-repair scaffolds dampen checkpoint signalling by counteracting the adaptor Rad9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

9 May 2019

The Saccharomyces cerevisiae 14-3-3 proteins Bmh1 and Bmh2 directly influence the DNA damage-dependent functions of Rad53.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

9 May 2019

Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

9 May 2019

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

9 May 2019

Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

9 May 2019

Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

9 May 2019

Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

3 references

9 May 2019

Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

9 May 2019

Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

9 May 2019

Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

DNA damage checkpoint signaling

1 reference

27 February 2018

RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P14737&geneProductId=UniProtKB:P14737

mitotic intra-S DNA damage checkpoint signaling

nucleotide-excision repair

1 reference

9 May 2019

RAD9, RAD24, RAD16 and RAD26 are required for the inducible nucleotide excision repair of UV-induced cyclobutane pyrimidine dimers from the transcribed and non-transcribed regions of the Saccharomyces cerevisiae MFA2 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

positive regulation of transcription by RNA polymerase II

1 reference

27 February 2018

A novel role for the budding yeast RAD9 checkpoint gene in DNA damage-dependent transcription.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P14737&geneProductId=UniProtKB:P14737

mitotic G1 DNA damage checkpoint signaling

1 reference

9 May 2019

Rad9 BRCT domain interaction with phosphorylated H2AX regulates the G1 checkpoint in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage

regulation of cell cycle

2 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

9 May 2019

Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

negative regulation of DNA replication

IGI

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

cellular response to DNA damage stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

double-strand break repair

1 reference

9 May 2019

Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

positive regulation of catalytic activity

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14737

DNA damage checkpoint signaling

IBA

positive regulation of transcription by RNA polymerase II

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14737

Rad9-like Rad53-binding domain, fungi

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P14737

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference