(Q27548480)

1 reference

1 January 2018

Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018

cysteine-type peptidase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

1 reference

14 February 2019

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

1 reference

14 February 2019

protein binding

4 references

14 February 2019

Molecular mechanism for the regulation of yeast separase by securin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

14 February 2019

Separase cooperates with Zds1 and Zds2 to activate Cdc14 phosphatase in early anaphase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

14 February 2019

High-quality binary protein interaction map of the yeast interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

14 February 2019

Downregulation of PP2A(Cdc55) phosphatase by separase initiates mitotic exit in budding yeast.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

cysteine-type endopeptidase activity

Disjunction of Homologous Chromosomes in Meiosis I Depends on Proteolytic Cleavage of the Meiotic Cohesin Rec8 by Separin

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

14 February 2019

Disjunction of Homologous Chromosomes in Meiosis I Depends on Proteolytic Cleavage of the Meiotic Cohesin Rec8 by Separin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

14 February 2019

Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

cell component

spindle pole body

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

1 reference

14 February 2019

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018

1 January 2018

1 January 2018

A novel role of the budding yeast separin Esp1 in anaphase spindle elongation: evidence that proper spindle association of Esp1 is regulated by Pds1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018

mitotic spindle

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

cytoplasm

centrosome

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

1 reference

14 February 2019

spindle

1 reference

14 February 2019

A novel role of the budding yeast separin Esp1 in anaphase spindle elongation: evidence that proper spindle association of Esp1 is regulated by Pds1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018

4 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018

7 November 2018

7 November 2018

A novel role of the budding yeast separin Esp1 in anaphase spindle elongation: evidence that proper spindle association of Esp1 is regulated by Pds1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018

3 references

7 November 2018

7 November 2018

A novel role of the budding yeast separin Esp1 in anaphase spindle elongation: evidence that proper spindle association of Esp1 is regulated by Pds1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03018&geneProductId=UniProtKB:Q03018

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

14 February 2019

14 February 2019

A novel role of the budding yeast separin Esp1 in anaphase spindle elongation: evidence that proper spindle association of Esp1 is regulated by Pds1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

14 February 2019

Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

HDA

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

4 references

14 February 2019

14 February 2019

A novel role of the budding yeast separin Esp1 in anaphase spindle elongation: evidence that proper spindle association of Esp1 is regulated by Pds1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

14 February 2019

Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

HDA

mitochondrion

mitotic spindle pole body

HDA

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

regulation of mitotic spindle elongation

biological process

The protease activity of yeast separase (esp1) is required for anaphase spindle elongation independently of its role in cleavage of cohesin

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

14 February 2019

The protease activity of yeast separase (esp1) is required for anaphase spindle elongation independently of its role in cleavage of cohesin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

mitotic sister chromatid segregation

IGI

meiotic chromosome separation

2 references

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

regulation of exit from mitosis

IGI

chromosome segregation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

1 reference

14 February 2019

apoptotic process

1 reference

14 February 2019

Cleavage of Mcd1 by caspase-like protease Esp1 promotes apoptosis in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

positive regulation of exit from mitosis

1 reference

14 February 2019

Positive feedback promotes mitotic exit via the APC/C-Cdh1-separase-Cdc14 axis in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03018

negative regulation of phosphoprotein phosphatase activity

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference