(Q27549405)

http://www.ebi.ac.uk/interpro/protein/Q00416

Helicase Sen1, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

ATP-dependent activity, acting on RNA

1 reference

8 April 2019

The sen1(+) gene of Schizosaccharomyces pombe, a homologue of budding yeast SEN1, encodes an RNA and DNA helicase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

5'-3' RNA helicase activity

1 reference

16 July 2018

The sen1(+) gene of Schizosaccharomyces pombe, a homologue of budding yeast SEN1, encodes an RNA and DNA helicase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00416&geneProductId=UniProtKB:Q00416

protein domain specific binding

ISS

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

ATP-dependent activity, acting on DNA

1 reference

8 April 2019

The sen1(+) gene of Schizosaccharomyces pombe, a homologue of budding yeast SEN1, encodes an RNA and DNA helicase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

5 references

8 April 2019

Multiple protein/protein and protein/RNA interactions suggest roles for yeast DNA/RNA helicase Sen1p in transcription, transcription-coupled DNA repair and RNA processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

8 April 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

8 April 2019

A global protein kinase and phosphatase interaction network in yeast.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

8 April 2019

The Glc7 phosphatase subunit of the cleavage and polyadenylation factor is essential for transcription termination on snoRNA genes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

8 April 2019

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

5'-3' DNA/RNA helicase activity

IPI

1 reference

16 July 2018

Saccharomyces cerevisiae Sen1 Helicase Domain Exhibits 5'- to 3'-Helicase Activity with a Preference for Translocation on DNA Rather than RNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00416&geneProductId=UniProtKB:Q00416

5'-3' DNA helicase activity

IDA

1 reference

16 July 2018

Saccharomyces cerevisiae Sen1 Helicase Domain Exhibits 5'- to 3'-Helicase Activity with a Preference for Translocation on DNA Rather than RNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00416&geneProductId=UniProtKB:Q00416

5'-3' DNA/RNA helicase activity

IDA

5'-3' DNA helicase activity

IBA

IDA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00416&geneProductId=UniProtKB:Q00416

16 July 2018

Inactivation of the yeast Sen1 protein affects the localization of nucleolar proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00416&geneProductId=UniProtKB:Q00416

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00416&geneProductId=UniProtKB:Q00416

1 reference

8 April 2019

Nrd1 interacts with the nuclear exosome for 3' processing of RNA polymerase II transcripts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

1 reference

16 July 2018

Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00416&geneProductId=UniProtKB:Q00416

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

8 April 2019

Inactivation of the yeast Sen1 protein affects the localization of nucleolar proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

site of double-strand break

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

1 reference

8 April 2019

The yeast SEN1 gene is required for the processing of diverse RNA classes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

DNA-dependent DNA replication maintenance of fidelity

1 reference

16 July 2018

Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00416&geneProductId=UniProtKB:Q00416

1 reference

8 April 2019

The PolyA tail length of yeast histone mRNAs varies during the cell cycle and is influenced by Sen1p and Rrp6p.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

regulation of transcription from RNA polymerase II promoter in response to DNA damage

1 reference

8 April 2019

Sen1p contributes to genomic integrity by regulating expression of ribonucleotide reductase 1 (RNR1) in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

RNA-binding protein Nrd1 directs poly(A)-independent 3'-end formation of RNA polymerase II transcripts

mRNA 3'-end processing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

termination of RNA polymerase II transcription

1 reference

8 April 2019

Genome-wide distribution of yeast RNA polymerase II and its control by Sen1 helicase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

DNA-templated transcription, termination

1 reference

8 April 2019

A bacterial-like mechanism for transcription termination by the Sen1p helicase in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

sno(s)RNA 3'-end processing

1 reference

8 April 2019

RNA-binding protein Nrd1 directs poly(A)-independent 3'-end formation of RNA polymerase II transcripts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

transcription-coupled nucleotide-excision repair

1 reference

16 July 2018

Sen1, the yeast homolog of human senataxin, plays a more direct role than Rad26 in transcription coupled DNA repair

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00416&geneProductId=UniProtKB:Q00416

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

Sen1, the homolog of human Senataxin, is critical for cell survival through regulation of redox homeostasis, mitochondrial function, and the TOR pathway in Saccharomyces cerevisiae

cell redox homeostasis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

transcription-coupled nucleotide-excision repair

3 references

8 April 2019

The yeast SEN1 gene is required for the processing of diverse RNA classes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00416

DNA-dependent DNA replication maintenance of fidelity

IBA

Helicase Sen1, N-terminal

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q00416

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference