(Q27550140)

Proliferating cell nuclear antigen, PCNA, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Proliferating cell nuclear antigen, PCNA, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Proliferating cell nuclear antigen, PCNA, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

DNA polymerase processivity factor activity

3 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

27 February 2018

DNA polymerase delta is highly processive with proliferating cell nuclear antigen and undergoes collision release upon completing DNA.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

27 February 2018

The yeast analog of mammalian cyclin/proliferating-cell nuclear antigen interacts with mammalian DNA polymerase delta

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

12 references

9 May 2019

Elg1, an alternative subunit of the RFC clamp loader, preferentially interacts with SUMOylated PCNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Subtle alterations in PCNA-partner interactions severely impair DNA replication and repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Arabidopsis thaliana Y-family DNA polymerase eta catalyses translesion synthesis and interacts functionally with PCNA2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Interaction with PCNA is essential for yeast DNA polymerase eta function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Proteome-wide protein interaction measurements of bacterial proteins of unknown function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

High-quality binary protein interaction map of the yeast interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Defining the budding yeast chromatin-associated interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Interaction between PCNA and diubiquitinated Mcm10 is essential for cell growth in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

identical protein binding

IPI

6 references

9 May 2019

Subtle alterations in PCNA-partner interactions severely impair DNA replication and repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Interaction with PCNA is essential for yeast DNA polymerase eta function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

The structure of a ring-opened proliferating cell nuclear antigen-replication factor C complex revealed by fluorescence energy transfer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

DNA polymerase processivity factor activity

IPI

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

DNA polymerase delta is highly processive with proliferating cell nuclear antigen and undergoes collision release upon completing DNA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

The yeast analog of mammalian cyclin/proliferating-cell nuclear antigen interacts with mammalian DNA polymerase delta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

1 reference

27 February 2018

Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

1 reference

9 May 2019

The DNA polymerase domain of pol(epsilon) is required for rapid, efficient, and highly accurate chromosomal DNA replication, telomere length maintenance, and normal cell senescence in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Localization of proteins that are coordinately expressed with Cln2 during the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

silent mating-type cassette heterochromatin assembly

IBA

biological process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

IEA

postreplication repair

1 reference

9 May 2019

regulation of DNA replication

IEA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

maintenance of DNA trinucleotide repeats

IEA

2 references

9 May 2019

Interactions among DNA ligase I, the flap endonuclease and proliferating cell nuclear antigen in the expansion and contraction of CAG repeat tracts in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Interactions among DNA ligase I, the flap endonuclease and proliferating cell nuclear antigen in the expansion and contraction of CAG repeat tracts in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

positive regulation of exodeoxyribonuclease activity

1 reference

9 May 2019

Stimulation of 3'-->5' exonuclease and 3'-phosphodiesterase activities of yeast apn2 by proliferating cell nuclear antigen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

leading strand elongation

IDA

1 reference

27 February 2018

Saccharomyces cerevisiae replication factor C. I. Purification and characterization of its ATPase activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands

IDA

1 reference

9 May 2019

Stimulation of 3'-->5' exonuclease and 3'-phosphodiesterase activities of yeast apn2 by proliferating cell nuclear antigen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

error-free translesion synthesis

IDA

1 reference

9 May 2019

PCNA monoubiquitylation and DNA polymerase eta ubiquitin-binding domain are required to prevent 8-oxoguanine-induced mutagenesis in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

establishment of mitotic sister chromatid cohesion

1 reference

9 May 2019

PCNA controls establishment of sister chromatid cohesion during S phase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

lagging strand elongation

2 references

9 May 2019

Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

1 reference

9 May 2019

Proliferating cell nuclear antigen (pol30) mutations suppress cdc44 mutations and identify potential regions of interaction between the two encoded proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast

meiotic mismatch repair

2 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

4 references

27 February 2018

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

27 February 2018

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

27 February 2018

The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

27 February 2018

Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15873&geneProductId=UniProtKB:P15873

nucleotide-excision repair

1 reference

9 May 2019

The N-degron protein degradation strategy for investigating the function of essential genes: requirement for replication protein A and proliferating cell nuclear antigen proteins for nucleotide excision repair in yeast extracts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

cellular response to DNA damage stimulus

IMP

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

5 references

9 May 2019

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

IBA

translesion synthesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15873

Proliferating cell nuclear antigen, PCNA, conserved site

IBA

has part(s)

1 reference

Proliferating cell nuclear antigen, PCNA, N-terminal

1 reference

Proliferating cell nuclear antigen, PCNA, C-terminal

1 reference

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference