(Q27550707)

histone-lysine N-methyltransferase activity

histone methyltransferase activity (H3-K79 specific)

2 references

4 references

21 June 2018

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04089&geneProductId=UniProtKB:Q04089

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04089&geneProductId=UniProtKB:Q04089

21 June 2018

Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04089&geneProductId=UniProtKB:Q04089

21 June 2018

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04089&geneProductId=UniProtKB:Q04089

1 reference

21 June 2018

Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04089&geneProductId=UniProtKB:Q04089

histone methyltransferase activity (H3-K79 specific)

IPI

5 references

14 February 2019

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

14 February 2019

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

14 February 2019

Interplay of chromatin modifiers on a short basic patch of histone H4 tail defines the boundary of telomeric heterochromatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

chromosome, subtelomeric region

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

14 February 2019

Role for the silencing protein Dot1 in meiotic checkpoint control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

global genome nucleotide-excision repair

IBA

biological process

1 reference

14 February 2019

Evidence that the histone methyltransferase Dot1 mediates global genomic repair by methylating histone H3 on lysine 79.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

Methylation of histone H3 lysine-79 by Dot1p plays multiple roles in the response to UV damage in Saccharomyces cerevisiae.

postreplication repair

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

recombinational repair

meiotic recombination checkpoint signaling

IGI

1 reference

14 February 2019

Role for the silencing protein Dot1 in meiotic checkpoint control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

mitotic intra-S DNA damage checkpoint signaling

IGI

1 reference

14 February 2019

Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

regulation of cell cycle

1 reference

14 February 2019

transcription, DNA-templated

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04089&geneProductId=UniProtKB:Q04089

DNA damage checkpoint signaling

3 references

21 June 2018

Methylation of histone H3 lysine-79 by Dot1p plays multiple roles in the response to UV damage in Saccharomyces cerevisiae.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04089&geneProductId=UniProtKB:Q04089

21 June 2018

Methylation of histone H3 lysine-79 by Dot1p plays multiple roles in the response to UV damage in Saccharomyces cerevisiae.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04089&geneProductId=UniProtKB:Q04089

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04089&geneProductId=UniProtKB:Q04089

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

histone H3-K79 methylation

4 references

14 February 2019

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

14 February 2019

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

14 February 2019

hDOT1L links histone methylation to leukemogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

nucleotide-excision repair

IDA

regulation of transcription, DNA-templated

IGI

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04089&geneProductId=UniProtKB:Q04089

regulation of transcription regulatory region DNA binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

negative regulation of heterochromatin assembly

IBA

1 reference

14 February 2019

Competition between Heterochromatic Loci Allows the Abundance of the Silencing Protein, Sir4, to Regulate de novo Assembly of Heterochromatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

chromatin organization

1 reference

14 February 2019

1 reference

14 February 2019

Dot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

1 reference

14 February 2019

Dot1 regulates nucleosome dynamics by its inherent histone chaperone activity in yeast.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

DNA damage checkpoint signaling

4 references

14 February 2019

Methylation of histone H3 lysine-79 by Dot1p plays multiple roles in the response to UV damage in Saccharomyces cerevisiae.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

14 February 2019

Methylation of histone H3 lysine-79 by Dot1p plays multiple roles in the response to UV damage in Saccharomyces cerevisiae.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04089

IBA

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference