(Q27551092)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20604

Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase family

1 reference

based on heuristic

inferred from protein domain or family

Calcineurin-like phosphoesterase

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

protein serine/threonine phosphatase activity

1 reference

9 May 2019

Sit4p/PP6 regulates ER-to-Golgi traffic by controlling the dephosphorylation of COPII coat subunits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

1 reference

9 May 2019

phosphoprotein phosphatase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

1 reference

9 May 2019

protein binding

10 references

9 May 2019

An in vivo map of the yeast protein interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

9 May 2019

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

9 May 2019

Distinct subsets of Sit4 holophosphatases are required for inhibition of Saccharomyces cerevisiae growth by rapamycin and zymocin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

9 May 2019

Proteome-wide protein interaction measurements of bacterial proteins of unknown function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

9 May 2019

Defining the budding yeast chromatin‐associated interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

9 May 2019

The yeast phosphotyrosyl phosphatase activator protein, yPtpa1/Rrd1, interacts with Sit4 phosphatase to mediate resistance to 4-nitroquinoline-1-oxide and UVA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

9 May 2019

Rapamycin activates Tap42-associated phosphatases by abrogating their association with Tor complex 1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

9 May 2019

A global protein kinase and phosphatase interaction network in yeast.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

9 May 2019

The EICP22 protein of equine herpesvirus 1 physically interacts with the immediate-early protein and with itself to form dimers and higher-order complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

cell component

nucleus

HDA

1 reference

9 May 2019

Global analysis of protein localization in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

HDA

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

3 references

9 May 2019

9 May 2019

The SIT4 protein phosphatase functions in late G1 for progression into S phase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

IDA

9 May 2019

Global analysis of protein localization in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

HDA

biological process

TOR signaling

1 reference

9 May 2019

TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

DNA repair

1 reference

9 May 2019

The yeast phosphotyrosyl phosphatase activator protein, yPtpa1/Rrd1, interacts with Sit4 phosphatase to mediate resistance to 4-nitroquinoline-1-oxide and UVA.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

fungal-type cell wall organization

1 reference

9 May 2019

Sit4 is required for proper modulation of the biological functions mediated by Pkc1 and the cell integrity pathway in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

actin cytoskeleton organization

1 reference

9 May 2019

Sit4 is required for proper modulation of the biological functions mediated by Pkc1 and the cell integrity pathway in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

1 reference

9 May 2019

cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

1 reference

9 May 2019

tRNA wobble uridine modification

1 reference

9 May 2019

A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

dephosphorylation

1 reference

9 May 2019

TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

intracellular signal transduction

1 reference

9 May 2019

Sit4 is required for proper modulation of the biological functions mediated by Pkc1 and the cell integrity pathway in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

cellular response to oxidative stress

1 reference

9 May 2019

Oxidant resistance in a yeast mutant deficient in the Sit4 phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

peptidyl-serine dephosphorylation

1 reference

9 May 2019

The ceramide-activated protein phosphatase Sit4p controls lifespan, mitochondrial function and cell cycle progression by regulating hexokinase 2 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

protein dephosphorylation

1 reference

9 May 2019

The TORC1 effector kinase Npr1 fine tunes the inherent activity of the Mep2 ammonium transport protein.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

G1/S transition of mitotic cell cycle

IGI

1 reference

8 April 2019

The SIT4 protein phosphatase functions in late G1 for progression into S phase

Saccharomyces Genome Database ID

SGD

S000002205

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

G1/S transition of mitotic cell cycle

IGI

1 reference

9 May 2019

The SIT4 protein phosphatase functions in late G1 for progression into S phase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20604

Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20604

Calcineurin-like phosphoesterase domain, ApaH type

1 reference

InterPro Release 71.0