(Q27551215)

http://www.ebi.ac.uk/interpro/protein/P47027

BRCT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

protein kinase activator activity

1 reference

9 May 2019

Yeast DNA replication protein Dpb11 activates the Mec1/ATR checkpoint kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

10 references

9 May 2019

S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

9 May 2019

Dpb11 activates the Mec1-Ddc2 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

9 May 2019

DNA-repair scaffolds dampen checkpoint signalling by counteracting the adaptor Rad9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

9 May 2019

DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

9 May 2019

A CDK-catalysed regulatory phosphorylation for formation of the DNA replication complex Sld2-Dpb11

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

9 May 2019

Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

9 May 2019

Damage-induced phosphorylation of Sld3 is important to block late origin firing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

9 May 2019

CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

9 May 2019

Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

9 May 2019

Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast

IPI

DNA polymerase binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

epsilon DNA polymerase complex

IDA

cell component

1 reference

24 April 2018

Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast

Saccharomyces Genome Database ID

SGD

S000003626

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47027&geneProductId=UniProtKB:P47027

DNA replication preinitiation complex

IDA

1 reference

9 May 2019

CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

1 reference

9 May 2019

Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47027&geneProductId=UniProtKB:P47027

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

Dpb11/TopBP1 plays distinct roles in DNA replication, checkpoint response and homologous recombination

IEA

mating type switching

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

mitotic G2 DNA damage checkpoint signaling

IMP

1 reference

9 May 2019

Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

double-strand break repair via break-induced replication

IGI

1 reference

9 May 2019

Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

DNA replication checkpoint signaling

IMP

1 reference

9 May 2019

DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

1 reference

14 February 2019

Eukaryotic DNA mismatch repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

activation of protein kinase activity

IEA

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

mitotic DNA replication checkpoint signaling

IEA

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P47027&geneProductId=UniProtKB:P47027

positive regulation of DNA replication origin binding

IBA

1 reference

9 May 2019

Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47027

1 reference

InterPro Release 71.0