(Q27551242)

English

Hir1p YBL008W

fungal protein found in Saccharomyces cerevisiae S288c

HIR1
Hir1p
YBL008W

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

10 December 2016

WD40/YVTN repeat-like-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32479

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32479

WD40-repeat-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P32479

TUP1-like enhancer of split, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

WD40 repeat, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

HIRA B motif domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

nucleosome binding

determination method

1 reference

21 June 2018

The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32479&geneProductId=UniProtKB:P32479

determination method

determination method

1 reference

21 June 2018

The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32479&geneProductId=UniProtKB:P32479

determination method

transcription corepressor activity

determination method

1 reference

21 June 2018

Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32479&geneProductId=UniProtKB:P32479

determination method

protein binding

determination method

6 references

9 May 2019

Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

9 May 2019

Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

9 May 2019

The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

9 May 2019

Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

9 May 2019

Defining the budding yeast chromatin-associated interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

9 May 2019

Yeast ASF1 protein is required for cell cycle regulation of histone gene transcription

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

identical protein binding

determination method

3 references

9 May 2019

Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

9 May 2019

Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

9 May 2019

Defining the budding yeast chromatin-associated interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

transcription corepressor activity

determination method

determination method

3 references

21 June 2018

The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32479&geneProductId=UniProtKB:P32479

determination method

21 June 2018

Replication-independent histone deposition by the HIR complex and Asf1.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32479&geneProductId=UniProtKB:P32479

determination method

21 June 2018

The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P32479&geneProductId=UniProtKB:P32479

determination method

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

determination method

4 references

9 May 2019

The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

9 May 2019

The HIR corepressor complex binds to nucleosomes generating a distinct protein/DNA complex resistant to remodeling by SWI/SNF.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

9 May 2019

Replication-independent histone deposition by the HIR complex and Asf1.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

biological process

negative regulation of transcription by RNA polymerase II

determination method

1 reference

9 May 2019

Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

transcription elongation from RNA polymerase II promoter

determination method

1 reference

9 May 2019

Evidence that Spt2/Sin1, an HMG-like factor, plays roles in transcription elongation, chromatin structure, and genome stability in Saccharomyces cerevisiae

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

transcription, DNA-templated

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

regulation of transcription, DNA-templated

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

mitotic sister chromatid segregation

determination method

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P32479

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Saccharomyces Genome Database ID

1 reference

20 March 2022

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