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Ste50p YCL032W
fungal protein found in Saccharomyces cerevisiae S288c
Ste50p
YCL032W
STE50
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P25344
subclass of
protein
1 reference
stated in
NCBI Gene
retrieved
10 December 2016
Entrez Gene ID
850325
part of
Ubiquitin-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P25344
Sterile alpha motif/pointed domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P25344
Ste50, sterile alpha motif, protein family
1 reference
based on heuristic
inferred from protein domain or family
Ras-associating (RA) domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Saccharomyces cerevisiae S288c
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P25344
encoded by
STE50
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P25344
molecular function
protein kinase regulator activity
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Functional characterization of the interaction of Ste50p with Ste11p MAPKKK in Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IDA
SAM domain binding
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Saccharomyces cerevisiae Ste50 binds the MAPKKK Ste11 through a head-to-tail SAM domain interaction
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IDA
protein binding
determination method
IPI
5 references
retrieved
9 May 2019
stated in
Adaptor functions of Cdc42, Ste50, and Sho1 in the yeast osmoregulatory HOG MAPK pathway.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IPI
retrieved
9 May 2019
stated in
A comprehensive two-hybrid analysis to explore the yeast protein interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IPI
retrieved
9 May 2019
stated in
Proteome survey reveals modularity of the yeast cell machinery
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IPI
retrieved
9 May 2019
stated in
A global protein kinase and phosphatase interaction network in yeast.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IPI
retrieved
9 May 2019
stated in
A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IPI
cell component
cytoplasm
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Requirement of STE50 for osmostress-induced activation of the STE11 mitogen-activated protein kinase kinase kinase in the high-osmolarity glycerol response pathway
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IDA
biological process
cell cycle
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P25344
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IEA
response to pheromone
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P25344
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IEA
osmosensory signaling pathway via Sho1 osmosensor
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Mutations in the SAM domain of STE50 differentially influence the MAPK-mediated pathways for mating, filamentous growth and osmotolerance in Saccharomyces cerevisiae
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IMP
signal transduction
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IEA
pheromone-dependent signal transduction involved in conjugation with cellular fusion
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Ste50p sustains mating pheromone-induced signal transduction in the yeast Saccharomyces cerevisiae.
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IMP
cellular response to heat
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Heat stress activates the yeast high-osmolarity glycerol mitogen-activated protein kinase pathway, and protein tyrosine phosphatases are essential under heat stress
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IMP
signal transduction involved in filamentous growth
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Ste50p is involved in regulating filamentous growth in the yeast Saccharomyces cerevisiae and associates with Ste11p
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IMP
regulation of protein kinase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IEA
MAPK cascade
determination method
IGI
IPI
2 references
retrieved
5 June 2018
stated in
Requirement of STE50 for osmostress-induced activation of the STE11 mitogen-activated protein kinase kinase kinase in the high-osmolarity glycerol response pathway
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25344&geneProductId=UniProtKB:P25344
determination method
IPI
retrieved
5 June 2018
stated in
Requirement of STE50 for osmostress-induced activation of the STE11 mitogen-activated protein kinase kinase kinase in the high-osmolarity glycerol response pathway
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25344&geneProductId=UniProtKB:P25344
determination method
IGI
osmosensory signaling MAPK cascade
determination method
IGI
IPI
2 references
retrieved
9 May 2019
stated in
Requirement of STE50 for osmostress-induced activation of the STE11 mitogen-activated protein kinase kinase kinase in the high-osmolarity glycerol response pathway
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IPI
retrieved
9 May 2019
stated in
Requirement of STE50 for osmostress-induced activation of the STE11 mitogen-activated protein kinase kinase kinase in the high-osmolarity glycerol response pathway
GOA
curator
SGD
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25344
determination method
IGI
has part(s)
Ste50, sterile alpha motif
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P25344
Ras-associating (RA) domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P25344
Identifiers
RefSeq protein ID
NP_009898
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
850325
UniProt protein ID
P25344
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P25344
Ensembl protein ID
YCL032W
1 reference
stated in
ensembl Release 106
Ensembl protein ID
YCL032W
Saccharomyces Genome Database ID
S000000537
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
850325
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